Pharm Exam 1, 2014

Front 1

Name 3 drug classes that are used only for HTN and CHF.

Back 1

ACEI/ARB, vasodilators, and diuretics

Front 2

Name a drug class that is good for HTN, CHF, arrhythmia, and angina.

Back 2

BB

Front 3

Name a drug class that is good for HTN, arrhythmia, and angina but not to be used with CHF.

Back 3

Ca channel blockers

Front 4

Name a drug class for CHF and arrhythmia tx only.

Back 4

Cardiac glycosides

Front 5

Name a drug class that treats arrhythmia only.

Back 5

Na channel blockers

Front 6

Name a drug class for CHF and angina.

Back 6

Nitrates

Front 7

The normal heart rate is determined by the cardiac action potential that originates from the SA node cells.

Back 7

True

Front 8

Pacemaker cells are atrioventricular cells.

Back 8

False

Front 9

One of the determinants for the cell-cell conduction of the cardiac action potential is the high electrical resistance at the gap junctions.

Back 9

False

Front 10

Arrhythmia is produced by only the abnormality of generation of cardiac action potential.

Back 10

False

Front 11

The action potential of the SA node cells has 5 phases.

Back 11

False

Front 12

A rapid Na inward current in cardiac ventricular cells determines the upstroke of the action potential.

Back 12

True

Front 13

When Na channels are completely or largely inactivated, any stimuli cannot induce large Na currents to depolarize cardiac myocytes, which is called effective refractory period of the the action potential.

Back 13

True

Front 14

The E-C coupling of cardiac cells depends upon intracellular Na levels, and cardiac contractility can by reduced due to the abnormality of E-C coupling.

Back 14

False

Front 15

Name another important determinant of action potential conductance between cardiac cells in addition to low electrical resistance at the gap junctions.

Back 15

Voltage difference between the cells

Front 16

Which event determines phase 3 depolarization of the action potential in ventricular cells?

Back 16

Outward K current

Front 17

The time period from phase 0 to membrane potential of -60mV in phase 3 if the effective refractory period. Cardiac cells are unable to produce what b/c Na channels are completely or largely inactivated?

Back 17

Produce a new action potential

Front 18

The coupling of the action potential on the cell membrane to the cardiac contraction depends upon what ion movement?

Back 18

Ca++ release from the SR

Front 19

What stimuli activates the baroreceptors during the baroreflex?

Back 19

Distention of the vascular walls

Front 20

Which statement indicates that the baroreflex is a neg feedback loop?

Back 20

Increased blood pressure causes vasodilation and bradycardia

Front 21

In response to decreased blood volume and activation of the renin-angiotensinII system, and decrease in atrial natriuretic peptide production will result in:

Back 21

Decrease renal Na excretion

Front 22

Ca channels blockers can be used to treat several CV diseases, but they cannot be used to treat:

Back 22

CHF

Front 23

Increase in ____ leads to more blood pumping into the aorta and thereby increases SBP.

Back 23

SV

Front 24

Abnormality of ______ reduces cardiac contractility and ______ is enhanced by drugs for treatment of heart failure.

Back 24

E-C coupling

Front 25

If _____ increases, DBP is elevated primarily.

Back 25

Peripheral arterial resistance

Front 26

A larger _____ will expand the vessel more and thereby increase mean arterial blood pressure.

Back 26

Circulatory blood volume