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5 Cards in this Set

  • Front
  • Back
Therapeutic Index
Toxic Dose50/Effective Dose50
-see pg 1 of PH1 for curve
50% toxicity
What kind of drug would have a flat therapeutic index curve?
Benzos
How to tell overlap of effective dose vs toxic dose curve
TD1/ED99
Lipoid barriers in the body
-entire lenght of G.I. tract
-Respiratory epithelium
-BBB
-Kidney tubules
-Placenta
Etc.
partition coef
solubility in something in oil/solubility in water.

-as it increases the cell membrane permeability increases.