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126 Cards in this Set
- Front
- Back
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Normasol-R
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replacement fluid
alkalinizing Mg+ |
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Lactated Ringers
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replacement fluid
alkalinizing Ca++ |
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Ringers
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replacement fluid
Ca++ |
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maintenance fluids
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1/2 the NaCl of replacement, have glucose, and more K+
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acetaminophen
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NSAID, contraindicated in cats
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tepoxalin
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NSAID, dual cox & 5-LO inhibitor
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asprin
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NSAID, antithrombotic
selective for cox-1 |
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carprofen
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NSAID
selective for cox-2 |
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deracoxib
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NSAID
selective for cox-2 |
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diclofenac
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NSAID, nonspecific cox inhibitor
used topically in horses for jt pain |
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etodolac
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NSAID
causes KCS/dry eye |
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firocoxib
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NSAID
highly selective cox-2 inhibitor |
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flunixin
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NSAID
approved in horses, cattle & swine |
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flurbiprofen
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NSAID
opthalmic agent |
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ibuprofen
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NSAID
contraindicated in dogs & ferrets |
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ketoprofen
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NSAID
labeled for use in horses cox-1 inhibitor |
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meloxicam
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NSAID
selective cox-2 inhibitor only FDA approved one for cats |
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etodolac
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NSAID
causes KCS/dry eye |
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naproxen
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NSAID
GI toxicity in dogs |
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firocoxib
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NSAID
highly selective cox-2 inhibitor |
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phenylbutazone
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NSAID
selective cox-1 inhibitor used a lot in horses, GI tox in dogs illegal for use in dairy cows |
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piroxicam
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NSAID, anti-neoplastic agent
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flunixin
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NSAID
approved in horses, cattle & swine |
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flurbiprofen
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NSAID
opthalmic agent |
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ibuprofen
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NSAID
contraindicated in dogs & ferrets |
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ketoprofen
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NSAID
labeled for use in horses cox-1 inhibitor |
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meloxicam
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NSAID
selective cox-2 inhibitor only FDA approved one for cats |
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naproxen
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NSAID
GI toxicity in dogs |
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phenylbutazone
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NSAID
selective cox-1 inhibitor used a lot in horses, GI tox in dogs illegal for use in dairy cows |
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piroxicam
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NSAID, anti-neoplastic agent
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robenacoxib
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NSAID
highly selective cox-2 inhibitor |
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hydrocortisone
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low potency glucocorticoid
high mineralcorticoid activity low HPAA suppression no alt. day therapy |
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cortisone
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low potency glucocorticoid
high mineralcorticoid activity low HPAA suppression alt. day therapy (not ideal) |
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prednisone
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intemed. potency glucocorticoid
low mineralcorticoid activity low HPAA suppression alt. day therapy |
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prednisolone
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intemed. potency glucocorticoid
low mineralcorticoid activity low HPAA suppression alt. day therapy |
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methylprednisolone
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intemed. potency glucocorticoid
low mineralcorticoid activity low HPAA suppression alt. day therapy |
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triamcinolone
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intemed. potency glucocorticoid
no mineralcorticoid activity intermed. HPAA suppression no alt. day therapy |
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flumethasone
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high potency glucocorticoid
no mineralcorticoid activity high HPAA suppression no alt. day therapy |
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dexamethasone
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high potency glucocorticoid
no mineralcorticoid activity high HPAA suppression no alt. day therapy |
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betamethasone
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high potency glucocorticoid
no mineralcorticoid activity high HPAA suppression no alt. day therapy |
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azathioprine
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immunosuppressant
antimetabolite (antiproliferative) |
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cyclophosphamide
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immunosuppressant/anti-neoplastic
alkylating agent, nitrogen mustard prodrug |
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cyclosporine
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immunosuppresant
calcineurin inhibitor opthalmic use |
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dapsone/danazol
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immunosuppresant
unknown MOA |
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methotrexate
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immunosuppresant/ anti-neoplastic
antimetabolite/ folic acid analog s-phase specific |
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mycophenolate
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immunosuppresant
antimetabolite (antiproliferative) |
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tacrolimus
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immunosuppresant
calcineurin inhibitor opthalmic use |
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chlorambucil
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immunosuppressant/anti-neoplastic
alkylating agent, nitrogen mustard |
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GnRH, gonadorelin, FSH, hcg, ecg
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gonadotropin products
ovulation induction/infertility therapy |
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oxytocin
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ecobolic agent
labor induction |
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altrenogest
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progestin
prevents cycling in mares |
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melengestrol acetate
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progestin
prevents cycling in small animals |
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megestrol acetate
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progestin
prevents cycling in feed animals |
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progestrone CIDR's
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progestin implant
synchronizes estrus |
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testosterone, boldenone, nandrolone, trenbolone, stanazolol
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androgens
Tx of catabolic dz states |
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finasteride
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antiandrogen
anti-hyperplasia |
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dinoprost & cloprosenol
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prostaglandins
estrus synchronization induction of abortion |
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domperidone
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dopamine antagonist
prolactin enhancer antiemetic |
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metoclopramide
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prolactin enhancer and prokinetic
dopamine antagonist, 5HT3 antagonist and 5HT4 agonist |
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DES
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steroid hormone (as is estradiol)
used in FS incontinence prohibited from use in food animals |
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PG2alpha
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induce partuition at term in goats and sows, some cows (not in horse or dog)
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diazapam & oxazepam
(benzodiazapines) |
appetite stimulants
GABA agonists |
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cyprohepadine
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appetite stimulant
serotonin antagonist, antihistamine |
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mirtazapine
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appetite stimulant
alpha2 blocker, serotonin antagonist and antihistamine |
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apomorphine
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emetic
Mu agonist |
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xylazine
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emetic
alpha2 agonist also alpha1 effects, low potency |
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hydrogen peroxide
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emetic
direct irritant |
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salt
|
emetic
direct irritant |
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ondansetron
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antiemetic
5HT3 antagonist |
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diphenhydramine
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antiemetic
antihistamine |
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cisapride
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prokinetic
5HT4 agonist works at entire GI tract |
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bethanechol
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prokinetic
cholinergic agonist |
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lidocaine
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prokinetic
mostly unknown MOA |
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acepromazine
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antiemetic
dopamine antagonist (alpha1 and muscarinic antagonist) |
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maropitant
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antiemetic
neurokinin antagonist |
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famotidine
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acid suppressant
H2 histamine antagonist |
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cimetidine
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acid suppressant
H2 histamine antagonist |
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ranitidine
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acid suppressant
H2 histamine antagonist |
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omeprazole
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acid suppressant
proton pump inhibitor |
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magnesium hydroxide
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acid neutralizer
(works on what's present, doesn't prevent) |
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misoprostol
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synthetic prostaglandin
protects GI mucosa |
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sucralfate
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attaches to stomach ulcers to aid healing
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loperamide
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anti-diarrheal
Mu agonist |
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diphenoxylate
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anti-diarrheal
Mu agonist |
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ractopamide, zilpaterol
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growth promotant / feed additive
beta agonist |
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monensin, sainomycin, laidlomycin
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growth promotant / feed additive
ionophore antimicrobials |
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chlortetracycline, oxytetracycline
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growth promotant / feed additive
non-ionophore antimicrobials |
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rBST
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injectable hormone
increased milk production |
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testosterone, estradiol benzoate, trenbolone, progresterone, zaranol
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anabolic implants
change gene expression -> increase protein synthesis and decrease catabolism |
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methimazole
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Tx of hyperthyroidism
inhibits thyroid peroxidase |
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propylthiouracil
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Tx of hyperthyroidism
inhibits thyroid peroxidase and 5'd ionidase not used due to autoimmune hemolytic anemia and thrombocytopenia |
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desoxycorticosterone pivalate
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mineralcorticoid
given as injection q 28 days no glucocorticoid activity |
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fludrocortisone
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mineralcorticoid
given orally daily some glucocorticoid activity |
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mitotane
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hyperadrenocorticism Tx
destruction of zonae fasciculata and reticularis -> decreased glucocorticoids only |
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trilostane
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hyperadrenocorticism Tx
inhibits conversion of pregnelone to progesterone -> decreased corticosteroids |
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ketoconazole
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hyperadrenocorticism Tx
inhibits conversion of lanosterol to cholesterol / blocks cyp450 enzymes -> decreased corticosteroids |
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L-deprenyl
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hyperadrenocorticism Tx
monoamine oxidase inhibitor (increased dopamine, decreased ACTH) |
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pergoglide
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dopamine agonist
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Regular, lispro, aspart
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fast acting insulin
for emergency use |
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NPH (isophane), protamine zinc, glargine, detemir
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long acting insulin
for chronic therapy |
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sulfonylureas
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oral hypoglycemic agent
inhibit K+ channels -> depol -> release of insulin |
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metaformin
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oral hypoglycemic agent
increase peripheral sensitivity to insulin |
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acarbose
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oral hypoglycemic agent
glucosidase inhibitor- blocks amylase |
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cisplatin
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antineoplastic
alkylating agent/platinum coord. complex contraindicated in cats |
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carmustine, lomustine
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antineoplastic
alkylating agent / nitrosureas form dna-dna/protein links |
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carboplatin
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antineoplastic
alkylating agent/platinum coord. complex |
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cytarabine
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antineoplastic
antimetabolite- S-cycle specific pyrimidine analog |
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5-flurouracil
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antineoplastic
antimetabolite- S-cycle specific pyrimidine analog contraindicated in cats |
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vincristine
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antineoplastic
M-phase specific inhibits microtubule fxn extravasion |
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vinblastine
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antineoplastic
M-phase specific inhibits microtubule fxn extravasion, more bone marrow supp |
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doxorubicin
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antineoplastic
topoisomerase blocker (antibiotic) cycle non-specific cardiotoxic, extravasion |
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L-asparginase
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antineoplastic
enzyme that deaminates asparginase G1 phase specific |
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toceranib
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antineoplastic
kinase inhibitor |
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isoflurane
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inhalant anesthetic
lower MAC=more potent higher blood/gas PC= slower induction |
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sevoflurane
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inhalant anesthetic
higher MAC=less potent lower blood/gas PC= faster induction |
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thiopental
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barbituate
GABA agonist shortest acting |
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pentobarbital
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barbituate
GABA agonist intermediate acting, used for euthanasia |
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phenobarbital
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barbituate
GABA agonist longest acting |
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ketamine
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dissociative anesthetic
NMDA receptor antagonist scheduled drug |
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tiletamine
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dissociative anesthetic
NMDA receptor antagonist combined with zolazepam |
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detomidine
|
alpha2 agonist
longest duration of action |
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dexmedetomidine
|
alpha2 agonist
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romifidine
|
alpha2 agonist
very selective |
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yohimbine
|
alpha2 antagonist
moderately selective |
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tolazoline
|
alpha2 antagonist
not selective |
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atipamezole
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alpha2 antagonist
very selective |
