Pharm Drug Adverse Effects Final Review Step 1 Usmle

Front 1

Adverse Effects of Drugs

Back 1

Drug

Front 2

Penicillin

Back 2

Hypersensitivity Rx
Hemolytic Anemia

Front 3

Methicillin

Back 3

Interstitial Nephritis

Front 4

Ampicillin Amoxi

Back 4

Pseudomembranous Colitis

Front 5

Carbenicillin

Back 5

Hypersensitivity Rx

Front 6

Cephalosporin

Back 6

nephrotoxicity increased w/ Aminoglycosides
Disulfiram-like w/ ethanol

Front 7

Atreonam

Back 7

Tx patients w/ renal insufficiency who cannot tolerate aminoglycosides

Front 8

Imipenem

Back 8

Seizures

Front 9

Vancomycin

Back 9

NOT

Nephrotoxicity
Ototoxicity
Thrombopheblitis

Red man Sx

Front 10

How do you prevent Red Man Sx?

Back 10

Antihistamine

Front 11

Antibiotic causes seizures?

Back 11

Imipenem

Front 12

B-lactam that causes nephrotoxicity and disulfiram like?

Back 12

Cephalosporin

Front 13

Causes thombophlebitis, nephrotoxicity, ototoxicity?

Back 13

Vaconmycin

Front 14

requires O2 for uptake, nephrotoxicity
otoxocitity when combined w/ loops? Teratogen

Back 14

Aminoglycosides

Front 15

Fanconi Sx???

Back 15

Tetracycline

Front 16

discoloration of teeth and inhibition of bone growth in children?

Back 16

tetracycline

Front 17

acute cholestatic hepatitis?

Eosinophilia...

Back 17

Macrolides

Front 18

Anemia
Aplastic anemia

Back 18

Chloramphenicol

Front 19

Pseudomembranous Colitis
Fever
Diarrhea

Back 19

Clindamycin

Front 20

hemolysis G6PD
nephrotoxicity
kernicterus
displaces warfarin from albumin

Back 20

Sulfonamide

Front 21

Megaloblastic Anemia
Leukopenia
granulocytopenia

Back 21

Trimetrophim

Front 22

Damages cartilage in kids?

Back 22

Fluoroquinolones

Front 23

Disulfiram-like?

Back 23

Metronidazole

Front 24

Neurotoxicity, acute tubular necrosis

Back 24

Polymixins

Front 25

Hemolysis G6PD, neurotoxcity, hepatoxicity?

Back 25

Isoniazid

Front 26

anti TB- related to optic neuritis?

Back 26

Ethambutol

can't see butts..

Front 27

All TB drugs are?

Back 27

hepatotoxic

Front 28

DOC for meningococcus?

Back 28

Rifampin

less minocycline

Front 29

Gonorrhea?

Back 29

Kill with an AX

ceftriAXone

Front 30

PCP pneunocystis?

Back 30

TMPX-SMX

Front 31

Hypotension, fever chills (shake and bake), nephrotoxicity, arrhythmias

Back 31

Amphoterrible

Amphotericin B

Front 32

Antifungal
gynecomastia, inhibits p450
fever chills?

Back 32

-azoles
fluconazole
ketoconazole

the areole grows!

Front 33

MOA flucytosine?

Back 33

inhibits DNA
competes w/ uracil

Front 34

Flucytosine gives you?

Back 34

flu like
nausea, vomiting diarrhea

bone marrow suppresion

Front 35

Causes build up of squalene?

Back 35

Terbinafine

Front 36

teratogenic
cardiogenic
consufion
increase warfarin metabolism?
fungus drug?

Back 36

Griseolfulvin

Front 37

Ataxia, diziness, slurred speech?Pat. w/ parkinson or influenza A?

Back 37

Amantadine

Front 38

Delirium, tremor, nephrotoxic?

Back 38

Acyclovir

Front 39

Nephrotoxicity in CMV retinits Tx

Back 39

Foscarnet

Front 40

If Tx of CMV retinitis Gangciclovir fails?

Back 40

Foscarnet

Front 41

Protease Inhibitors?

Back 41

hyperglycemia

Front 42

Name a protease inhibitor that causes hyperglycemia, insulin resistance?

Back 42

saquinavir
ritonavir
indinavir

Front 43

HIV therapy drug causes pancreatitis?

Back 43

Didanosine
Zalcitabine

Front 44

WHat two drugs can't be combiend in HIV therapy?

Back 44

Didanosine
Zalcitabine

Front 45

HIV therapy megaloblastic anemia?

Back 45

AZT

Front 46

What drug is used for Hep B?

Back 46

Lamivudine

Front 47

WHat drug is used for Hep C?

Back 47

Rivabirin

Front 48

Dyskinesia?

Back 48

Levodopa

Front 49

What epilepsy drug is Liver Fx tests monitoring needed?

Back 49

Carbamazepine

Front 50

Neural Tube Deffects in Epilepsy Drug?

Back 50

Valproate

decreases folate absorption

Front 51

Epilepsy drug causes sedation, tolerance, dependence?

Back 51

Benzodiazepines

Front 52

Epilepsy drug causes diplopia, ataxia, induction of P450
liver toxicity
agranulocytosis?

Back 52

Carbamazepine

Front 53

Epiplespy drug causes Steven-Johnson Sx, urticaria, lethargy, headache?

Back 53

Ethosuximide

Front 54

Epilepsy drug causes nystagmus, diplopia, ataxia, sedation, gingival hyperplasia, hirsutism, anemia, teratogenic?

Back 54

phenytoin

Front 55

Rash, Steven-Johsons Sx?

Back 55

Lamotrigine

Front 56

epilepsy drug causes sedation, movement disorder?

Back 56

gabapentin

Front 57

epilepsy drug causes mental dulling, sedation, KIDNEY STONES, weight LOSS?

Back 57

Topiramate

Front 58

nystagmus, diplopia, lethargy, ataxia, gingival hyperplasia, megaloblastic anemia?

Back 58

phenytoin

Front 59

Neuroleptic Malignant Syndrome
Tardive Dyskinesia?

Back 59

Antipsychotics

Front 60

What is neuroleptic malignant sx?

Back 60

rigidity, sweating, hyperpyrexia

Front 61

anti-pyschotic causes agranulocytosis?

Back 61

clozapine

Front 62

what anty-psychotic does NOT cause tardive dyskinesia?

Back 62

CLozapine

Front 63

Polyuria (ADH antagonist)
SIADH
RV atrialization?

Back 63

Lithium

Front 64

Drug used for Bedwetting?

Back 64

Imipramine

Front 65

Drug used for OCD?

Back 65

clomipramine

Front 66

Tricyclic cause?

Back 66

urinary retention
atropine like symptoms

Front 67

Toxic Effects Tricyclics?

Back 67

3C
cardiotoxicity
convulsions
coma

Front 68

What drug causes hallucinations in elderly?
confusion?

Back 68

Tricyclics

Front 69

What durg causes hyperthermia, muscle rigidity, cardiovascular collapse?

Back 69

SSRI mixed with MAO

Front 70

What drug causes sexual dysfucntion of SSRIs?

Back 70

sertraline

Front 71

Antidepressant causes priapism?

Back 71

Trazodone

Front 72

What Antidepressant does NOT cause sexual S/E?

Back 72

bupoprion

Front 73

Heterocyclic causes sedation, increase cholesterol, increase apetite?

Back 73

Mirtazapine

aunt Mirta is hungry and high cholestrol only wants to sleep