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64 Cards in this Set

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ARB
Losartan: the only Angiotensin 2 Receptor Blocker

NB: competitively inhibit AT1 "Angiotensin 2 Receptor Type 1"
(what retarded bullshit)

One of the 4 drugs which will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone (Inspra)
Most Appropriate Pain Killer for Terminal Cancer
Morphine
Losartan
Losartan: the only Angiotensin 2 Receptor Blocker

NB: competitively inhibit AT1 "Angiotensin 2 Receptor Type 1"
(what retarded bullshit)

One of the 4 drugs which will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone (Inspra)
Metoprolol
β-blocker used for angina pectoris: decreases cardiac oxygen demand, but may precipitate CHF
Rx for angina pectoris which may precipitate CHF
Metoprolol

↓ oxygen demand, ↓ fnx
The important equations for Vd, CL, Kel, λ, Css
.
ACEI's
enalapril & captopril

↑ kilkalrenin → dry cough

will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone ie Inspra)
enalapril
ACEI

↑ kilkalrenin → dry cough

will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone ie Inspra)
captopril
ACEI

↑ kilkalrenin → dry cough

will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone ie Inspra)
Cholestyramine
bile acid resin: prevents bile resorption

↓ LDL

pts hate this drug: tastes aweful, GI upset

gallstones possible, less likely than with fibrates Gemofibrozil
most likely anti-hyperlipidemic agent to cause gallstones
Gemfibrozil (Lopid) a fibric acid derivative
also in this class: Fenofibrate (TriCor)

PPARγ ligand → ↑ LPL → VLDL catabolism

SE: hepatic damage, gallstones, myopathy
Gemfibrozil (Lopid)
a fibric acid derivative
also in this class: Fenofibrate (TriCor)

PPARγ ligand → ↑ LPL → VLDL catabolism

SE: hepatic damage, gallstones, myopathy
Fenofibrate (TriCor)
a fibric acid derivative
also in this class: Gemfibrozil (Lopid)

PPARγ ligand → ↑ LPL → VLDL catabolism

SE: hepatic damage, gallstones, myopathy
Niacin
inhibits hepatic VLDL production

most potent ↑ [HDL]

Flushing, hyperglycemia, hyperuricemia
-statins
inhibit HMGcoA reductase

mostpotent ↓ in LDL

Side Effects: hepatotoxicity, rhabdo
Bleomycine
anti-leukemia drug

pulmonary fibrosis
Coagulytics in Pregnancy
Warfarin Contraindicated

Hepatrin used

LMW heparin = Enoxaprin (Lovenox)
Which drugs are used in which seizures
Tonic/Clonic- Phenytoin, Carbamazepine

Status Epilepticus: Diazepam, Lorazepam

Abscence: Ethosuximide, Valproic Acid

Mixed: Valproic Acid
Enoxaprin (Levonox)
LMW Heparin
Safe in pregnancy
Clopidegrel (Plavix)
inhibits ADP receptors
↓ platelet aggregation
Abciximab (ReoPro)
inhiibts GPIIb/IIIa receptors

extremely expensive $k's/injnx
Warfarin (Coumadin)
inhibits reduction of Vitamin K, prevents synthesis of 2, 7, 9 and X
Mycophenydate
blocks MPD needed for de novo purine synth only in T's and B's

mild side effects
IFN α2b
used in HepB and C
IFNα2a Roferon
Hairy Cell Leukemia
Kaposi's sarcoma
Imuran
6MP in vivo
anti-CD3
reverses acute rejection
IL-2
stimulates M∅and B cells
Zidovudine (Retrovir)
dTP analogue
nucleoside RTI
safe in pregnancy
Neutropenia worse with Gancicylovir or Tyloenol
Anti-herpes med safe in pregnancy
Acyclovir
Thyrolytic safe in pregnancy
PTU
Cimetidine & Warfarin
Cimetidine decreases Metzm of Warfarin
Cholinesterase inhibitors
Neostigmine

Edrophonium is short acting, used to Dx myasthenia gravis
Edorphonium
short acting cholinesterase inhibitor used to Dx myasthenia gravis
-curiums
non-depolarizing NMJ blockers, can be countered with cholinesterase inhibitors (neostigmine)
Neostigmine
cholinesterase inhibitor
pilocarpine
cholinergic acognist
brimonidine (alphagam)
α2 agonist, decreases aqueous humor production
timolol
β blocker, used v glaucoma

local application, susceptible to systemic absorption → avoid in asthmatics
best Tx for DKA
regular insulin
COX2 specific inhibitor
Celebrex
non-depolarizing nmj blockers
-curiums
β-lactam safe in pts with penicillin allergy
aztreonam
nefidipine
a calcium channel blocker

-strongest vasodilation
-least effect heart automaticity/condxn
→ most likely to produce reflex tachycardia
verpamil
calcium channel blocker

-most effect at SA/AV nodes
-least vasodilatory effect
→ least likely to produce reflex tachycardia
Diltazapam
a calcium channel blocker

-intermediate effect on SA/AV nodes
-intermediate effect on vasodilation
--reflex tachycardia possible
Magnesium vs Aluminum
Magnesium: produces diarrhea
Aluminum: produces constiptation
Loperimide
opiod agonist: tx for diarrhea
Metoclopramide
D2 agonist, ↑ GI motility
teratogenic
Dopamine for parkinsons
effectiveness decreases w/ time
divide doses to decreases nausea
red swollen feet (like Bromocriptine)
Danazol
weak progestin

DOC for endometriosis
DOC for endometriosis
Danazol
Fluatmide
androgen receptor antagonist
prostate CA
methyltestosterone
testosterone
Etoposide
Topoisomerase inhibitor used v testicular CA

myelosuppression is most likely toxicity
Tx for severe p vivax
treatment for ANY severe malaria is Quinine/Quinidine
changing the pH of urine
Bicarb alkalinizes
NH4Cl acidifies
ropinerole
restless leg syndrome
Deferoxamine
Chelates Iron
Fomepizole (Antizol)
inhibits alcohol dehydrogenase-Antifreeze
Methylene blue
-- Nitrites: oxides hemoglobin to methemaglobin well water, chocolate blood
Succimer (Chemet)-
for lead poisoning
cyanide
Amyl-nitrite:
Organosphosphates:
atropine, PAM