Pharm: Cumulative Supplement

Front 1

ARB

Back 1

Losartan: the only Angiotensin 2 Receptor Blocker

NB: competitively inhibit AT1 "Angiotensin 2 Receptor Type 1"
(what retarded bullshit)

One of the 4 drugs which will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone (Inspra)

Front 2

Most Appropriate Pain Killer for Terminal Cancer

Back 2

Morphine

Front 3

Losartan

Back 3

Losartan: the only Angiotensin 2 Receptor Blocker

NB: competitively inhibit AT1 "Angiotensin 2 Receptor Type 1"
(what retarded bullshit)

One of the 4 drugs which will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone (Inspra)

Front 4

Metoprolol

Back 4

β-blocker used for angina pectoris: decreases cardiac oxygen demand, but may precipitate CHF

Front 5

Rx for angina pectoris which may precipitate CHF

Back 5

Metoprolol

↓ oxygen demand, ↓ fnx

Front 6

The important equations for Vd, CL, Kel, λ, Css

Back 6

.

Front 7

ACEI's

Back 7

enalapril & captopril

↑ kilkalrenin → dry cough

will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone ie Inspra)

Front 8

enalapril

Back 8

ACEI

↑ kilkalrenin → dry cough

will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone ie Inspra)

Front 9

captopril

Back 9

ACEI

↑ kilkalrenin → dry cough

will ↑ lifespan (ACEI's, ARB's, β-blockers, & Spirolactone/Eplerenone ie Inspra)

Front 10

Cholestyramine

Back 10

bile acid resin: prevents bile resorption

↓ LDL

pts hate this drug: tastes aweful, GI upset

gallstones possible, less likely than with fibrates Gemofibrozil

Front 11

most likely anti-hyperlipidemic agent to cause gallstones

Back 11

Gemfibrozil (Lopid) a fibric acid derivative
also in this class: Fenofibrate (TriCor)

PPARγ ligand → ↑ LPL → VLDL catabolism

SE: hepatic damage, gallstones, myopathy

Front 12

Gemfibrozil (Lopid)

Back 12

a fibric acid derivative
also in this class: Fenofibrate (TriCor)

PPARγ ligand → ↑ LPL → VLDL catabolism

SE: hepatic damage, gallstones, myopathy

Front 13

Fenofibrate (TriCor)

Back 13

a fibric acid derivative
also in this class: Gemfibrozil (Lopid)

PPARγ ligand → ↑ LPL → VLDL catabolism

SE: hepatic damage, gallstones, myopathy

Front 14

Niacin

Back 14

inhibits hepatic VLDL production

most potent ↑ [HDL]

Flushing, hyperglycemia, hyperuricemia

Front 15

-statins

Back 15

inhibit HMGcoA reductase

mostpotent ↓ in LDL

Side Effects: hepatotoxicity, rhabdo

Front 16

Bleomycine

Back 16

anti-leukemia drug

pulmonary fibrosis

Front 17

Coagulytics in Pregnancy

Back 17

Warfarin Contraindicated

Hepatrin used

LMW heparin = Enoxaprin (Lovenox)

Front 18

Which drugs are used in which seizures

Back 18

Tonic/Clonic- Phenytoin, Carbamazepine

Status Epilepticus: Diazepam, Lorazepam

Abscence: Ethosuximide, Valproic Acid

Mixed: Valproic Acid

Front 19

Enoxaprin (Levonox)

Back 19

LMW Heparin
Safe in pregnancy

Front 20

Clopidegrel (Plavix)

Back 20

inhibits ADP receptors
↓ platelet aggregation

Front 21

Abciximab (ReoPro)

Back 21

inhiibts GPIIb/IIIa receptors

extremely expensive $k's/injnx

Front 22

Warfarin (Coumadin)

Back 22

inhibits reduction of Vitamin K, prevents synthesis of 2, 7, 9 and X

Front 23

Mycophenydate

Back 23

blocks MPD needed for de novo purine synth only in T's and B's

mild side effects

Front 24

IFN α2b

Back 24

used in HepB and C

Front 25

IFNα2a Roferon

Back 25

Hairy Cell Leukemia
Kaposi's sarcoma

Front 26

Imuran

Back 26

6MP in vivo

Front 27

anti-CD3

Back 27

reverses acute rejection

Front 28

IL-2

Back 28

stimulates M∅and B cells

Front 29

Zidovudine (Retrovir)

Back 29

dTP analogue
nucleoside RTI
safe in pregnancy
Neutropenia worse with Gancicylovir or Tyloenol

Front 30

Anti-herpes med safe in pregnancy

Back 30

Acyclovir

Front 31

Thyrolytic safe in pregnancy

Back 31

PTU

Front 32

Cimetidine & Warfarin

Back 32

Cimetidine decreases Metzm of Warfarin

Front 33

Cholinesterase inhibitors

Back 33

Neostigmine

Edrophonium is short acting, used to Dx myasthenia gravis

Front 34

Edorphonium

Back 34

short acting cholinesterase inhibitor used to Dx myasthenia gravis

Front 35

-curiums

Back 35

non-depolarizing NMJ blockers, can be countered with cholinesterase inhibitors (neostigmine)

Front 36

Neostigmine

Back 36

cholinesterase inhibitor

Front 37

pilocarpine

Back 37

cholinergic acognist

Front 38

brimonidine (alphagam)

Back 38

α2 agonist, decreases aqueous humor production

Front 39

timolol

Back 39

β blocker, used v glaucoma

local application, susceptible to systemic absorption → avoid in asthmatics

Front 40

best Tx for DKA

Back 40

regular insulin

Front 41

COX2 specific inhibitor

Back 41

Celebrex

Front 42

non-depolarizing nmj blockers

Back 42

-curiums

Front 43

β-lactam safe in pts with penicillin allergy

Back 43

aztreonam

Front 44

nefidipine

Back 44

a calcium channel blocker

-strongest vasodilation
-least effect heart automaticity/condxn
→ most likely to produce reflex tachycardia

Front 45

verpamil

Back 45

calcium channel blocker

-most effect at SA/AV nodes
-least vasodilatory effect
→ least likely to produce reflex tachycardia

Front 46

Diltazapam

Back 46

a calcium channel blocker

-intermediate effect on SA/AV nodes
-intermediate effect on vasodilation
--reflex tachycardia possible

Front 47

Magnesium vs Aluminum

Back 47

Magnesium: produces diarrhea
Aluminum: produces constiptation

Front 48

Loperimide

Back 48

opiod agonist: tx for diarrhea

Front 49

Metoclopramide

Back 49

D2 agonist, ↑ GI motility
teratogenic

Front 50

Dopamine for parkinsons

Back 50

effectiveness decreases w/ time
divide doses to decreases nausea
red swollen feet (like Bromocriptine)

Front 51

Danazol

Back 51

weak progestin

DOC for endometriosis

Front 52

DOC for endometriosis

Back 52

Danazol

Front 53

Fluatmide

Back 53

androgen receptor antagonist
prostate CA

Front 54

methyltestosterone

Back 54

testosterone

Front 55

Etoposide

Back 55

Topoisomerase inhibitor used v testicular CA

myelosuppression is most likely toxicity

Front 56

Tx for severe p vivax

Back 56

treatment for ANY severe malaria is Quinine/Quinidine

Front 57

changing the pH of urine

Back 57

Bicarb alkalinizes
NH4Cl acidifies

Front 58

ropinerole

Back 58

restless leg syndrome

Front 59

Deferoxamine

Back 59

Chelates Iron

Front 60

Fomepizole (Antizol)

Back 60

inhibits alcohol dehydrogenase-Antifreeze

Front 61

Methylene blue

Back 61

-- Nitrites: oxides hemoglobin to methemaglobin well water, chocolate blood

Front 62

Succimer (Chemet)-

Back 62

for lead poisoning

Front 63

cyanide

Back 63

Amyl-nitrite:

Front 64

Organosphosphates:

Back 64

atropine, PAM