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19 Cards in this Set

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Nandrolone
Anabolic steroid like testosterone
Mechanism similar to testosterone, except that it is not broken down into DHT
Oxandrolone
Anabolic steroid like DHT
Binds androgen receptors--does not convert to estrogen.
Faloxifene
SERM
E agonist in bone, antagonist in breast
Tamoxifene
SERM
E agonist in bone, antagonist in breast
Clomiphene
SERM
Binds ER in pituitary=>inhibits neg feedback=>increases GnRH and FSH/LH for ovulation
Fulvestrant
Pure ER antagonist
Inhibits dimerization of occupied ER in all tissues
Mifepristone
Progesterone antagonist
Blocks P=>loss of maintainence of uterine lining
Ulpristal
Progesterone antagonist
Blocks P=>loss of maintainence of uterine lining
Lerozole
Estrogen synthesis inhibitor
Inhibits aromatase (last step in synth)
Anastrozole
Estrogen synthesis inhibitor
Inhibits aromatase (last step in synth)
Exemestane
Estrogen synth inhibitor
Inhibits aromatase (needed for last step)
Finasteride
5a reductase inhibitor
Prevents conversion of T to DHT
Dutasteride
5a reductase inhibitor
Prevents conversion of T to DHT
Ketoxonazole
Inhibits adrenal/gonadal steroid synth
Displaces E and DHT from SHBP. Increasese E:T ratio
Flutamide
Non-steroidal AR antagonist
Prevents DHT and testosterone from bind to receptors
Bicalutamide
Non-steroidal AR antagonist
Prevents DHT and testosterone from bind to receptors
Cyproterone
Steroidal AR antagonist
Prevents DHT and testosterone from bind to receptors
Spironolactone
AR antagonist
Inhibits both aldo and testoeterone
Danazol
T derivitive
Binds to androgen, progesterone, and glucocorticoid receptors