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19 Cards in this Set
- Front
- Back
- 3rd side (hint)
Nandrolone
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Anabolic steroid like testosterone
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Mechanism similar to testosterone, except that it is not broken down into DHT
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Oxandrolone
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Anabolic steroid like DHT
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Binds androgen receptors--does not convert to estrogen.
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Faloxifene
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SERM
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E agonist in bone, antagonist in breast
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Tamoxifene
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SERM
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E agonist in bone, antagonist in breast
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Clomiphene
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SERM
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Binds ER in pituitary=>inhibits neg feedback=>increases GnRH and FSH/LH for ovulation
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Fulvestrant
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Pure ER antagonist
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Inhibits dimerization of occupied ER in all tissues
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Mifepristone
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Progesterone antagonist
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Blocks P=>loss of maintainence of uterine lining
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Ulpristal
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Progesterone antagonist
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Blocks P=>loss of maintainence of uterine lining
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Lerozole
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Estrogen synthesis inhibitor
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Inhibits aromatase (last step in synth)
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Anastrozole
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Estrogen synthesis inhibitor
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Inhibits aromatase (last step in synth)
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Exemestane
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Estrogen synth inhibitor
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Inhibits aromatase (needed for last step)
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Finasteride
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5a reductase inhibitor
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Prevents conversion of T to DHT
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Dutasteride
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5a reductase inhibitor
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Prevents conversion of T to DHT
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Ketoxonazole
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Inhibits adrenal/gonadal steroid synth
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Displaces E and DHT from SHBP. Increasese E:T ratio
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Flutamide
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Non-steroidal AR antagonist
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Prevents DHT and testosterone from bind to receptors
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Bicalutamide
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Non-steroidal AR antagonist
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Prevents DHT and testosterone from bind to receptors
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Cyproterone
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Steroidal AR antagonist
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Prevents DHT and testosterone from bind to receptors
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Spironolactone
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AR antagonist
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Inhibits both aldo and testoeterone
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Danazol
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T derivitive
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Binds to androgen, progesterone, and glucocorticoid receptors
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