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25 Cards in this Set

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First generation H1 receptor antagonists

Diphenhydramine (Benadryl)
Chlorpheniramine (ChlorTrimeton)
Clemastine (Tavist)
Demenhydrinate (Dramamine)
Promethazine (Phenergan)

First generation H1 receptor antagonist Adverse Reactions


Drowsiness, dry mouth, constipation, HA, dizziness, N/V, sedation, hypotension, respiratory depression, insomnia, nervousness, tremors, urinary retention, renal toxicity, thickening of bronchial secretions, photosensitivity, hypoglycemia

Second Generation H1 receptor antagonists

cetirizine (Zyrtec)


fexofenadine (allegra)


loratadine (Claritin)

Second Generation H1 receptor anatagonists Adverse Effects

Dry mouth, HA, N/V, dizziness, urinary retention, hypotension, insomnia, nervousness, tremors

H1 receptor antagonist nursing implications

Avoid alcohol and opoids


May cause insomnia


Lowers seizure threshold


Do not give with MAOI inhibitors


Do not give to breastfeeding pts


Check blood sugar

Antihistamines -vs- decongestants

Antihistamines dry secrections


Decongestants drain secrections


Intranasal Corticosteroids

Fluticasone (Flonase)


Beclomethasone (Beconase AQ, Qvar)


Flunisolide (Nasalide)


Mometasone (Nasonex)


Triaminolone acetonide (Nasacort AQ)

Intranasal Corticosteroids Adverse Effects

None serious, nasal burning, sneezing, dryness

Intranasal Corticosteroids Nursing Implications

Pts should avoid swallowing


Pts need to continue 2-3 for best results


Take before exposure to allergen

Nasal decongestants: Sympathomimetics

Oxymetazoline (Afrin 12 hour, Neosynephrine 12 hour)



Pseudoephedrine (Sudafed, Actifed)



Phenylephrine (Afrin, Neosynephrine)

Sympathomimetic nasal decongestants adverse reactions

Intranasal: Nasal irritation, burning, sneezing, dryness, HA, rebound congestion



PO: nervousness, insomnia, HA, dry mouth, dysrhythmia, severe vasoconstriction



Vasoconstriction = HIGH BP

Sympathomimetic nasal decongestants nursing implications

Do not use for more than 3 days- rebound congestion



Use with caution in Pts with hypertension


Avoid caffine


No MAOIs



May decrease the action of beta-blockers

Anticholinergic Nasal Decongestants

ipatropium bromide (Atrovent, Combivent)

Anticholinergic nasal decongestants adverse effects

Nasal irritation, burning, sneezing, dryness, cough, HA, urinary retention

Antitussives -Opoids

codeine


hydrocodone with homatropine (Hycodan)

Opoid Antitussives Adverse Effects

N/V, constipation, confusion, dizziness, sedation, hypotension, seizures, bradycardia, respiratory failure, fatigue, hypotension

Opoid Antitussives Nursing Implications

Monitor for bronchial constriction


Increase fluids

Non-opoid antitussives

- Raise cough threshold



Dextromethorphan (Delsym, Robitussin)



Benzonatate (Tessalon) [numbs cough receptors in the lungs]

Non-opoid antitussives Adverse Reactions

Drowsiness, constipation, HA, GI upset, CNS depression, insomnia, respiratory depression

Non-opiod antitussives Nursing Implications

Contraindicated in chronic cough


No alcohol or other CNS depressants


DO NOT CHEW TESSALON

Expectorant antitussives

guaifenesin (Mucinex, Robitussin) [reduces thickness of bronchial secretions]


Expectorant antitussives adverse reactions

Drowiness, HA, GI upset

Expectorant antitussives Nursing Implications

Do not give to children under 2



Increase fluids

Mucolytic antitussives

acetylcysteijne (Acetadote, Mucomyst)

Mucolytic antitussives adverse effects

Nausea, N/V, bronchospasm [rotten egg odor]