Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
23 Cards in this Set
- Front
- Back
tetracycline mechanism of action
|
bind 30S ribosomal subunit- bacteriostatic
|
|
tetracycline drug with broadest spectrum and less common resistance
|
tigecycline
|
|
side effect includes deposition in developing bones and teeth
|
tetracyclines
|
|
macrolide mechanism of action
|
bind 50S ribosomal subunit- bacteriostatic
|
|
macrolide with least resistance
|
telithromycin
|
|
macrolide that does not inhibit CYP450
|
azithromycin
|
|
cardiac side effect of macrolide antibiotics
|
QT prolongation
|
|
clindamycin class
|
lincosamide
|
|
clarithromycin class
|
macrolide
|
|
mechanism of action for clindamycin
|
bind to 50S ribosomal subunit- bacteriostatic
|
|
quinupristin-dalfopristin class
|
streptogramin
|
|
mechanism of action for streptogramins
|
bind to 50S ribosomal subunit- bactericidal
|
|
associated with grey baby syndrome
|
chloramphenicol
|
|
mechanism of action for chloramphenicol
|
bind to 50S ribosomal subunit- bacteriostatic
|
|
linezolid class
|
oxazolidinone
|
|
linezolid mechanism of action
|
binds to 23S RNA of 50S subunit- bacteriostatic
|
|
antibiotic that can cause serotonin syndrome when combined with an SSRI
|
linezolid
|
|
why do tetracyclines have little effect on mammalian protein synthesis?
|
an active efflux mechanism prevents intracellular accumulation
|
|
used as a backup drug for salmonella and for treatment of pneumococcal/meningococcal meningitis in beta-lactam sensitive patients
|
chloramphenicol
|
|
occurs as a consequence of using outdated tetracyclines
|
Fanconi's Syndrome (form of renal tubular necrosis)
|
|
macrolide that allows levels to be higher in tissues and phagocytes rather than plasma
|
azithromycin
|
|
main use of clindamycin
|
severe infections caused by anaerobes such as bacteroides
|
|
hematologic adverse effects of linezolid
|
thrombocytopenia and neutropenia
|