Pharm Chapter 18 Glossary

Front 1

Agonists

Back 1

Drugs with a specific receptor affinity that produce a “mimic” response.

Front 2

Angina

Back 2

Paroxysmal chest pain caused by myocardial ischemia.

Front 3

Antagonists

Back 3

Drugs that bind to adrenergic receptors and inhibit or block the action of neurotransmitters.

Front 4

Cardioprotective

Back 4

Term applied to B-blockers to inhibit stimulation of the heart by circulating catecholamines.

Front 5

Cardioselective b-blockers

Back 5

The b-blocking drugs that are selective for b1-adrenergic receptors. Also called B1-blocking drugs.

Front 6

Dysrhythmias

Back 6

Irregular heart rhythms; almost always called arrhythmias in clinical practice.

Front 7

Extravasation

Back 7

Leaking of fluid from the blood vessel into the surrounding tissues, as in the case of an infiltrated intravenous infuion.

Front 8

Glycogenolysis

Back 8

The production of glucose from glycogen in the liver, which is reduced by B-blockers.

Front 9

Intrinsic sympathomimetic activity

Back 9

Paradoxical action of some B-blocking drugs (e.g., acebutolol) that mimics the action of the sympathetic nervous system.

Front 10

Lipophilicity

Back 10

Chemical attraction of a substance (e.g., drug molecule) to lipid or fat molecules.

Front 11

Nonselective b-blockers

Back 11

The b-blocking drugs that block both b1- and B2-adrenergic receptors.

Front 12

Orthostatic hypotension

Back 12

Abnormally low blood pressure that occurs when a person assumes a standing position from a sitting or lying position.

Front 13

Oxytocics

Back 13

Drugs used to treat postpartum and postabortion bleeding caused by uterine relaxation and enlargement. They stimulate the smooth muscle of the uterus to contract.

Front 14

Pheochromocytoma

Back 14

A vascular adrenal gland tumor that is usually benign but secretes epinephrine and norepinephrine and thus often causes central nervous system stimulation and substantial blood pressure elevation.

Front 15

Sympatholytics

Back 15

Another name for adrenergic antagonist.

Front 16

Vaughan Williams classification

Back 16

System of classifying antidysrhythmic drugs.