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27 Cards in this Set

  • Front
  • Back

absorption

a drug is moved from site of administration to body fluids, first process during pharmacokinetics

adverse reaction

undesirable drug effect

allergic reaction

immediate hypersensitive reaction by the immune system; it presents as itching, hives, swelling, and difficulty breathing

anaphylactic shock

sudden, severe hypersensitivity reaction with symptoms that progress rapidly and may result in death if not treated

angioedema

localized wheals or swellings in subcutaneous tissues or mucous membranes, which may be due to allergic response

controlled substances

drugs that have the potential for abuse and dependency, both physical and physiological

cumulative drug effect

when the body is unable to metabolize and excrete one dose of a drug before the next is given

distribution

drug moves from circulation to body tissue or a target site

drug idiosyncrasy

any unusual or abnormal response that differs from the response normally expected to a specific drug and dosage

drug tolerance

decreased response to a drug, requiring an increase in dosage to achieve the desired effect

excretion

elimination of a drug from the body

first pass effect

action by which an oral drug is absorbed and carried directly to the liver, where it is inactivated by enzymes before it enters the general blood stream

half life

time required for the body to eliminate 50% of a drug

herbal medicines

type of complementary/alternative therapy that uses plants or herbs to treat various disorders

hypersensitivity

undesirable reaction produced by a normal immune system

metabolism

drug is changed to a form that can be excreted

metabolite

inactive form of the original form

non prescription drug

drugs that are designated by the U.S. Food and Drug Administration (FDA) to be safe and obtainable without a prescription (OTC drugs)

pharmaceutic

pertaining to the phase during which a drug dissolves in the body

pharmacodynamics

study of the drug mechanisms that produce biochemical or physiologic changes in the body

pharmacokinetics

study of drug transit after administration

physical dependence

habitual use of a drug, where negative physical withdrawal symptoms result from abrupt discontinuation

prescription drugs

drugs the federal government has designated as potentially harmful unless their use is supervised by a licensed health care provider

psychological dependecy

compulsion or craving to use a substance to obtain a pleasurable experience

receptor

a reactive site on the surface of a cell; when a drug binds to and interacts with the receptor, a pharmacologic response occurs

teratogen

drug or substance that causes abnormal development of the fetus, leading to deformities

toxic

poisonous or harmful