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27 Cards in this Set
- Front
- Back
absorption |
a drug is moved from site of administration to body fluids, first process during pharmacokinetics |
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adverse reaction |
undesirable drug effect |
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allergic reaction |
immediate hypersensitive reaction by the immune system; it presents as itching, hives, swelling, and difficulty breathing |
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anaphylactic shock |
sudden, severe hypersensitivity reaction with symptoms that progress rapidly and may result in death if not treated |
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angioedema |
localized wheals or swellings in subcutaneous tissues or mucous membranes, which may be due to allergic response |
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controlled substances |
drugs that have the potential for abuse and dependency, both physical and physiological |
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cumulative drug effect |
when the body is unable to metabolize and excrete one dose of a drug before the next is given |
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distribution |
drug moves from circulation to body tissue or a target site |
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drug idiosyncrasy |
any unusual or abnormal response that differs from the response normally expected to a specific drug and dosage |
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drug tolerance |
decreased response to a drug, requiring an increase in dosage to achieve the desired effect |
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excretion |
elimination of a drug from the body |
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first pass effect |
action by which an oral drug is absorbed and carried directly to the liver, where it is inactivated by enzymes before it enters the general blood stream |
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half life |
time required for the body to eliminate 50% of a drug |
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herbal medicines |
type of complementary/alternative therapy that uses plants or herbs to treat various disorders |
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hypersensitivity |
undesirable reaction produced by a normal immune system |
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metabolism |
drug is changed to a form that can be excreted |
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metabolite |
inactive form of the original form |
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non prescription drug |
drugs that are designated by the U.S. Food and Drug Administration (FDA) to be safe and obtainable without a prescription (OTC drugs) |
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pharmaceutic |
pertaining to the phase during which a drug dissolves in the body |
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pharmacodynamics |
study of the drug mechanisms that produce biochemical or physiologic changes in the body |
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pharmacokinetics |
study of drug transit after administration |
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physical dependence |
habitual use of a drug, where negative physical withdrawal symptoms result from abrupt discontinuation |
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prescription drugs |
drugs the federal government has designated as potentially harmful unless their use is supervised by a licensed health care provider |
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psychological dependecy |
compulsion or craving to use a substance to obtain a pleasurable experience |
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receptor |
a reactive site on the surface of a cell; when a drug binds to and interacts with the receptor, a pharmacologic response occurs |
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teratogen |
drug or substance that causes abnormal development of the fetus, leading to deformities |
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toxic |
poisonous or harmful |