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55 Cards in this Set
- Front
- Back
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iododeoxyuridine
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anti-herpes; abnormal base
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trifluridine
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anti-herpes; abnormal base
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ara-A
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anti-herpes; doesn't require viral TK
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DOC for HSV keratitis
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trifluridine
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imiquimod
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adjunct for HSV-2 and HPV warts; stimulates the immune system
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docosanol
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anti-viral adjunct; highly lipophilic, prevents viral entry of anything with a lipid coat like HSV-1 and 2; Flu A, RSV, HHV-6
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azidothymidine and FYI
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NRTI; nucleoside; RNA chain terminator; 1st antiretroviral
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dideoxycytidine
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NRTI; pyrimidine nucleoside; RNA chain terminator
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dideoxyinosine
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NRTI; purine nucleoside; competes with dATP and causes RNA chain terminator
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lamivudine and side effect
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NRTI; pyrimidine nucleoside; RNA chain terminator; pancreatitis
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stavudine and side effect
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NRTI; pyrimidine nucleoside; peripheral neuropathy
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abacavir and S/E
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NRTI; purine nucleoside; rash, diarrhea, weakness
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ribavarin and MOA
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purine nucleside; used for Influenza and RSV; interferes with GMP formation!!!!
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interferon alpha
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Hep C and condylomata accuminatum
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entacavir
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hep B tx
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thymosin
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immune enhancer for Hep B tx
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amantidine
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flu A
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ramantidine
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flu A; inhibits uncoating
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zanamivir and route of admin
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inhibits viral neuraminidase; flu A and B; given naZally
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oseltamavir and route of admin
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inhibits viral neuraminidase; flu A and B; common prophylaxis for travelers; given Orally
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foscarnet
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anti-CMV
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nevirapine
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NNRTI
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common letters for NNRTI
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-vir-
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efavirenz
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NNRTI
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delaviridin
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NNRTI
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hydroxyurea
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NNRTI
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indinavir
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PI
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saquinavir
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PI
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ritonavir and side effect
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PI; inhibits CYP450
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common ending for protease inhibitors
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-navir
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nelfinavir
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PI
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amprenavir
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PI
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cidofovir and toxicity; FYI
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nucleotide analog; nephrotoxic; 1st nucleotide analog
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adefovir
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nucleotide analog
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Which drug should you give L-carnitine for as an adjunct?
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adefovir
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formivirsen
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anti-CMV; complementary to mRNA of CMV
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acyclovir
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HSV; purine nucleoside
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ganciclovir
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CMV retinitis; purine nucleoside
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penciclovir
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use for Painful fever blisters; purine nucleoside
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famciclovir
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genital herpes and VZV; purine nucleoside
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valacyclovir
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used for genital herpes and VZV; purine nucleoside
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tenofovir
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nucleotide analog
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What drugs can be used for HSV keratitis?
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Idu, TFT, and ara-A
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1st oral antiviral
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acyclovir
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1st CMV antiviral
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ganciclovir
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1st IV antiviral
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ara-A
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1st anti-viral for HIV
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AZT
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raltegravier
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integrase blocker for HIV tx
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enfurvitide
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blocks gp41 and prevents fusion (note that this differs from maraviroc which inhibits entry)
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maraviroc
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binds CCR5 and prevents entry of HIV
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What is the main side effect of NNRTIs
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rash
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What is a S/E of delaviridin
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rash and alteration in blood counts
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peptidomimetic anti-viral
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enfurvitide
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Are the anti-herpes drugs mostly purines or pyrimidines?
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mostly purines (-cyclovirs) exceptions TFT and Idu
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Are the anti-retrovirals mostly purines or pyrimidines?
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mostly pyrimidines with exception being ddI
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