Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/22

Click to flip

22 Cards in this Set

  • Front
  • Back
glycoprotein rec IIb and IIIa
fibrinogen rec
inc bining of firbrinogen to rec which inc plt binding
ASA
txa2 inhib
prevent mi and stroke
irrev bind cox 1and2
antiplt and antiinf
cause ulcer and blding
Dipyridamole
inhib plt agg
and phosphodiesterase in high lvls
prevents emblization of prosthetic valves
Indomethacin
inhib cox 1,2, and lipooxygenase
use w. neonate to close PDA
Clopidogrel(plavix)
Ticlopidine
antiplt
inhib ADP rec
use instead of ASA for mi and stroke
cause TTP,leukopenia,hemorrage
agranulocytosis w/ Tic
combine asa w/ clop
Cilostazol
antiplits
PDE3 inhib
for tx of intermittant claudication or PAD
Iv Abciximaba
Eptifibatide
Tirofiban
antiplts
inhib IIb/IIIa rec by keeping fibrinogen from binding=no plt agg
use for acute coronary disease and
angioplasty
Antithrombin 3
inactivates factors 2,9,10,11,12
which are part of intrinsic and 2 is common so works vivo and vitro
LMW Heparin
anticoag
works vivo and vitro b/c inc antithromb3 by enhancing the serine protease activity
-safe in preg
side effects:
blding,thrombocytopenia,osteoperosis
Protamine
antidote to heparin
Dalteparin
Enoxaparin
Danaparoid
anticoags
Enox-lovenox
Dana-safe in hypersens to heparin
Argatroban
Bivalirudin
thrombin inhib
inhib directly
biv-unstable angina w/ PTCA
Warfarin
-po
-inhib vit k factor synth 1972
-blocks gamma carboxylation factors
-works in liver
-only works in vivo
-no preg
-side effects are blding
skin nec-in ppl w/ protein C def
purple toe synd
bone defects
protein c
activated by thrombomodulin and thrombin ->combines w/ protein S to inactivate factor 5 and 8
Enoxaparin
lovenox
LMWH
works against factor 10 more than 2
works longer than hep
prevents DVT
cuases:
hemmorage,thrombocytopenia,local irritation
not for prosthetic heart valves
anticoag side effects
spinal and epidural hematoma
thrombocyto
hyperlipidemia
Phytonadione
antidote to warfarin
vit k1
PT/INR
checks warfarin pthwy
is for extrisic
>2.5 times norm
PTT
monitors heparin
should be 1.5 -2.5 times norm
Alteplse
Reteplase
TPA
recomb DNA
clot specific
no allergy rxn
Streptokinase
like TPA
non specific
causes allergies and hypotn
dec plasminogen and 5 and 8 in circ
Amino caproic acid
antidote to fibrinolytics