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86 Cards in this Set
- Front
- Back
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Bethanechol
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Muscarinic Receptor Direct Agonist
GI disorders, stimulate atonic bladder, Xerostomia |
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Carbachol
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Muscarinic Receptor Direct Agonist
Miotic |
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Methacholine
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Muscarinic Receptor Direct Agonist
Dx asthma Xerostomia |
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Pilocarpine
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Muscarinic Receptor Direct Agonist
Glaucoma (2nd line for open angle) Xerostomia |
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Muscarine/Arecoline
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Muscarinic Receptor Direct Agonist
Glaucoma (2nd line for open angle) Xerostomia |
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Atropine
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Muscarinic Antagonists
mydriasis/cycloplegia decrease hyper-motility of bladder low dose: bradycardia high dose: tachycardia (block M2) |
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Scopolamine
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Muscarinic Antagonists
prevention of motion sickness |
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Ipratropium
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Synthetic/Semisynthetic Muscarinic Antagonists
Asthma/COPD (not 1st line) |
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Tiotropium
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Synthetic/Semisynthetic Muscarinic Antagonists
COPD |
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Homatropine
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Synthetic/Semisynthetic Muscarinic Antagonists
Mydriasis/cycloplegia (shorter duration then atropine) |
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Cyclopentolate
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Synthetic/Semisynthetic Muscarinic Antagonists
Mydriasis/cycloplegia (shorter duration then atropine) |
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Tropicamide
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Synthetic/Semisynthetic Muscarinic Antagonists
Mydriasis/cycloplegia (shorter duration then atropine) |
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Benztropine
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Synthetic/Semisynthetic Muscarinic Antagonists
reserves for parkinsonism/extrapyramidal effects of antipsychotics |
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Trihexyphenidyl
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Synthetic/Semisynthetic Muscarinic Antagonists
reserves for parkinsonism/ extrapyramidal effects of antipsychotics |
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Gylcopyrrolate
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Synthetic/Semisynthetic Muscarinic Antagonists
inhibit GI motility/prevents bradycardia |
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Tolterodine
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Synthetic/Semisynthetic Muscarinic Antagonists
Overactive bladder |
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Edrophonium
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Indirect Acting Cholinergic Agonist (Acetlcholinesterases)
Dx of myasthenia gravis |
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Neostigmine
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Indirect Acting Cholinergic Agonist (Acetlcholinesterases)
stimulate bladder/GIT antidote for tubocurarine |
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Physostigmine
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Indirect Acting Cholinergic Agonist (Acetlcholinesterases)
stimulate bladder/GIT antidote for tubocurarine |
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Pyridostigmine/Ambenonium C
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Indirect Acting Cholinergic Agonist (Acetlcholinesterases)
Tx of myasthenia gravis |
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Echothiophate
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Indirect Acting Cholinergic Agents (AChE)
Organophosphate Glaucoma |
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Malathion
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Indirect Acting Cholinergic Agents (AChE)
Organophosphate safe insecticide |
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Parathion
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Indirect Acting Cholinergic Agents (AChE)
Organophosphate dangerous insecticide |
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Tabun, Sarin, Soman
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Indirect Acting Cholinergic Agents (AChE)
nerve gases/toxic |
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Tacrine
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Indirect Acting Cholinergic Agents (AChE)
Alzheimer disease |
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Donepezil
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Indirect Acting Cholinergic Agents (AChE)
Alzheimer disease |
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Rivastigmine
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Indirect Acting Cholinergic Agents (AChE)
Alzheimer disease |
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Galantamine
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Indirect Acting Cholinergic Agents (AChE)
Alzheimer disease |
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Pralidoxime
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Regenerates AChE
organophosphate insecticide poisoning |
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Nicotine
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Cholinergic - Nicotinic Receptor Agonists
Smoking cessation |
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Lobeline
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Cholinergic - Nicotinic Receptor Agonists
Smoking cessation |
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Tetramethylammonium (TMA)/ Dimethylphenyl Piperazinium (DMPP)
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Cholinergic - Nicotinic Receptor Agonists
experimental (not followed by ganglionic blockade) |
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Varenicline
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Cholinergic - Nicotinic Receptor Agonists
Smoking cessation |
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Nicotine
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Antinicotinic Agents
Ganglion Blocker |
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Tetraethylammonium (TEA)
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Antinicotinic Agents
Ganglion Blocker |
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Hexamethonium (C6)
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Antinicotinic Agents
Ganglion Blocker |
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Tubocurarine
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Antinicotinic Agents
nondepolarizing competitive blocker |
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Succinylcholine
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Antinicotinic Agents
Depolarizing blocker |
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Hemichonlinium-3
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Antinicotinic Agents
ACh synthesis inhibitor prevent uptake of choline (blocks CHT) |
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Vasmicol
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Antinicotinic Agents
ACh synthesis inhibitor blocks ACh-H+ antiporter |
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Mecamylamine
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Antinicotinic Agents
Ganglion blocker HTN in pts w/ acute aortic dissection |
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Trimetaphan
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Antinicotinic Agents
Ganglion blocker HTN in pts w/ acute aortic dissection |
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Botulinum Toxin
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Antinicotinic Agents
ACh release inhibitor degrades synaptobreven thus prevents synaptic vesicle fusion = inhibit ACh release |
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Epinephrine
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Nonselective Direct Adrenergic Agonists
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Norepinephrine
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Nonselective Direct Adrenergic Agonists
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Dopamine
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Nonselective Direct Adrenergic Agonists
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Fenoldopam
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Nonselective Direct Adrenergic Agonists (D1 agonist)
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Amphetamine
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Indirect Acting Adrenergic Agonists
increase BP |
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Methylphenidate
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Indirect Acting Adrenergic Agonists
ADHD in kids |
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Tyramine
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Indirect Acting Adrenergic Agonists
Adverse: pt on MAOI -> serious vasoconstriction |
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Oxymethazoline
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Indirect Acting Adrenergic Agonists
Nasal decongestion/opthalmic hyperemia |
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Xylomethazoline
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Indirect Acting Adrenergic Agonists
Nasal decongestion/opthalmic hyperemia |
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Pseudoephedrine
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Indirect Acting Adrenergic Agonists
Nasal decongestion in combo w/ H1 antagonist |
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Phenylproanolamine
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Indirect Acting Adrenergic Agonists
Nasal decongestion in combo w/ H1 antagonist |
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Phenylephrine
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a1 agonist
nasal decongestant/mydriatic increase BP and terminate SVT |
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Clonidine
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Partial a2 agonist
HTN |
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Methyldopa
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Partial a2 agonist
HTN during pregnancy |
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Brimonidine
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a2 agonist
Glaucoma |
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Phenoxybenzamine
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Nonselective a blocker
HTN/Pheochromocytoma (prior to surgery) |
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Phentolamine
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Nonselctive a blocker
Pheochromocytoma (short term control of HTN) |
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Prazosin
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a1 blocker
HTN/BPH |
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Terazosin
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a1 blocker
HTN/BPH |
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Doxazosin
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a1 blocker
HTN/BPH |
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Tamsulosin
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a1 blocker
HTN/BPH decreased incidence of orthostatic hypotension |
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Yohimbine
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a2 blocker
erectile dysfunction |
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Lebetalol
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Selective a1 and B blocker
Partial B2 agonist HTN |
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Carvedilol
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Selective a1 and B blocker
HTN/CHF |
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Isoproterenol
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B agonist
increases HR and contractility |
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Dobutamine
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Full B agonist
increase CO in CHF |
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Terbutaline
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B2 agonist
bronchodilation Tx of status asthmaticus |
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Albuterol (Salbutamol)
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B2 agonist
inhaled to relieve bronchospasm |
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Salmeterol
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B2 agonist
Asthma (prolonged duration of action) |
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Formoterol
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B2 agonist
Asthma (prolonged duration of action) |
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Propranolol
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B-blocker
HTN/Angina/MI |
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Nadolol
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B-blocker
longtime management of HTN/angina |
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Timolol
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B-blocker
intraocular HTN or open angle glaucoma |
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Pindolol
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Partial B agonist
HTN |
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Atenolol
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B1 antagonist
HTN (diabetics on insulin) |
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Metoprolol
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B1 antagonist
HTN (diabetics on insulin) |
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Esmolol
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B1 antagonist
HTN (diabetics on insulin) ultra short acting |
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a-methyltyrosine (Metyrosine)
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NE synthesis inhibition
Pheochromocytoma rarely used |
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Reserpine
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Obsolete NE storage inhibition
HTN in past |
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Guanethidine
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NE storage/release inhibition
HTN |
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MAOIs
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NE metabolism inhibition
Depression and Parkinson disease |
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Cocaine
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Monoamine re-uptake inhibition
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TCA
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NE-reuptake inhibition
Depression |
