Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/19

Click to flip

19 Cards in this Set

  • Front
  • Back
Hemorrhagic cystitis
Cyclophosphamide
Leucovorin rescue
Methotrexate
Thymidylate synthase
5-FU
Thymineless death
5-fluorouracil (5-FU)
Xanthine oxidase (allopurinol interaction)
6-mercaptopurine (6-MP)
HPGRT
6-mercaptopurine (6-MP), 6-thioguanine (6-TG)
Covalent modification of N7 guanine
Alkylating agents
Mesna
Cyclophosphamide
Brain tumors and neurotoxicity
Nitrosoureas
Nephrotoxicity (mannitol)
Cisplatin
Non-myelosuppressive
Cisplatin
Topoisomerase I inhibitors
Camptothecins (topotecan, irinotecan)
Topoisomerase II inhibitors
Podophyllotoxins (etoposide, teniposide)
Irreversible cumulative cardiac toxicity
Anthracyclines (daunorubicin, doxorubicin)
Pulmonary toxicity
Bleomycin
CCS intercalator/strand breaker
Bleomycin
Prevents microtubule polymerization (assembly)
Vinca alkaloids (vincristine, vinblastine)
Causes stabilization of microtubule polymerization (prevents disassembly)
Taxanes (paclitaxel, docetaxel)
High neurotoxicity (areflexia, peripheral neuritis, paralytic ileus)
Vincristine