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15 Cards in this Set
- Front
- Back
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Nonselective alpha-blocking drug, long acting and irreversible, and used to treat pheochromocytoma. Blocks 5-HT, so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis
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Phenoxybenzamine
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Nonselective alpha-blocking drug, short acting and reversible, used for rebound HTN from rapid clonidine withdrawal, and Raynaud's phenomena
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Phentolamine
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Selective Alpha 1 blocker used for hypertension, BPH, may cause first dose orthostatic hypotension
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Prazosin, terazosin, doxazosin
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Selective Alpha 2 blocker used for impotence (controversial effectiveness)
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Yohimbine
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SelectiveB1 Receptor blockers that may be useful in treating patients even though they have asthma
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Acebutolol, atenolol, esmolol, metoprolol
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Combined alpha and beta blocking agents that may have application in treatment of CHF
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Labetalol and carvedilol
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Beta blockers partial agonist activity (intrinsic sympathomimetic activity) cause some bronchodilation and may have an advantage in treating patients with asthma
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Pindolol and acebutolol
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This beta blocker lacks local anesthetic activity (decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma
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Timolol
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This parenteral beta blocker is a short acting (minutes)
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Esmolol
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This beta blocker is the longest acting
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Nadolol
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These beta blockers are less lipid soluble
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Acebutolol and atenolol
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This beta blocker is highly lipid soluble and may account for side effects such as nightmares
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Propranolol
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Clinical uses of these agents include treatment of HTN, angina, arrhythmias, and chronic CHF
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Beta blockers
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Toxicity of these agents include bradycardia, AV blockade, exacerbation of acute CHF, signs of hypoglycemia may be masked (tachycardia, tremor, and anxiety)
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Beta blockers
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These Beta blockers decrease aqueous secretion
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Timolol (nonselective), betaxolol (selective)
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