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11 Cards in this Set
- Front
- Back
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Available bisphosphonates
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Alendronate, etidronate, risedronate, pamidronate, tiludronate, and zoledronic acid
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MOA of Bisphosphonates
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Inhibits osteoclast bone resorption
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Only bisphosphonates available IV
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Etidronate
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Uses of bisphosphonates
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Osteoporosis, Paget's disease, and osteolytic bone lesions, and hypercalcemia from malignancy
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Major SE of bisphosphonates
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Chemical esophagitis
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Bisphosphonates that cannot be used on continuous basis because it caused osteomalacia
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Etidronate
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Used for prevention of postmenopausal osteoporosis in women
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Estrogen (HRT-Hormone replacement therapy)
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Increase bone density, also being tested for breast CA tx.
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Raloxifene (SERM-selective estrogen receptor modulator)
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Used intranasally and decreases bone resorption
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Calcitonin (salmon prep)
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Used especially in postmenopausal women, dosage should be 1500 mg
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Calcium
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Vitamin given with calcium to ensure proper absorption
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Vitamin D
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