Pharm

Front 1

Epinephrine

Back 1

α1α2β1β2D1 agonist – does not penetrate BBB

Front 2

Norepinephrine

Back 2

α1α2β2 agonist – not used clinically

Front 3

Entacapone

Back 3

Inhibits peripheral COMT – prevents Parkinson tx “wearing off”

Front 4

Phenelzine

Back 4

Inhibits MAO; treats parkinson’s and severe depression

Front 5

Ephedrine

Back 5

α1β1 agonist indirectly; direct β2 agonist; CNS stimulation, long duration

Front 6

Pseudoephedrine

Back 6

α1β1 agonist; indirect only; CNS stimulation

Front 7

Phenylpropanolamine

Back 7

β1 agonist; Dietary aid, increases risk of stroke

Front 8

Amphetamines

Back 8

Releases NE, blocks reuptake; tx ADD and narcolepsy

Front 9

Methamphetamines

Back 9

Increased SNS; No clinical use; irritability, hallucinations; memory loss; permanent loss of DA and 5HT neurons

Front 10

Cocaine

Back 10

Blocks reuptake of DA in CNS/NE in PNS; used as local anesthetic and for vasoconstriction, fast acting

Front 11

Tyramine

Back 11

Competes w/ Dopamine; not used clinically, found in foods. Releases NE, MAO converts it to inactive products

Front 12

Reserpine

Back 12

Blocks NE release; used for CNS tranquilization and HTN; causes depression, suicide, increased GI tone, nasal stuffiness, weight gain

Front 13

Methyldopa

Back 13

Interferes with NE release; HTN; causes sedation, dry mouth; competes with dopamine for transport into vesicles to function as false transmitter

Front 14

α-methyltyrosine

Back 14

Inhibits NE synthesis

Front 15

α-methyldopa hydrazine

Back 15

Inhibits L-DOPA synthesis in the periphery; used with L-DOPA in treatment of parkinson’s

Front 16

Phenylephrine

Back 16

α1 agonist – reduces IOP

Front 17

Clonidine

Back 17

α2 agonist – CNS opiate withdrawal

Front 18

α-methyl NE

Back 18

α2 agonist - hypertension

Front 19

Phentolamine

Back 19

α1α2 antagonist – not used clinically - reversible

Front 20

Phenoxybenzamine

Back 20

α1α2 antagonist – not used clinically - irreversible

Front 21

Prazosin

Back 21

short acting α1 antagonist; tx HTN w/o tachycardia; causes dizziness

Front 22

Terazosin

Back 22

longer acting α1 antagonist; tx HTN w/o tachycardia; causes dizziness

Front 23

Tamsulosin

Back 23

α1a antagonist; treats BPH

Front 24

Isoproterenol

Back 24

β1 β2 agonist; very powerful

Front 25

Dopamine

Back 25

β1—some α1β2D1 agonist; cardiac stimulant; short acting; less likely to cause dysrhythmia

Front 26

Dobutamine

Back 26

β1 agonist—some α1β2 agonist

Front 27

Albuterol

Back 27

β2 agonist; tx tachycardia, tremor, hyperglycemia, hypokalemia

Front 28

Terbutaline

Back 28

β2 agonist; tx tachycardia, tremor, hyperglycemia, hypokalemia

Front 29

Salmeterol

Back 29

β2 agonist; tx tachycardia, tremor, hyperglycemia, hypokalemia

Front 30

Ritodrine

Back 30

β2 agonist

Front 31

Propranolol

Back 31

β1 β2 antagonist; can cause heart failure in diseased hearts; can cause bronchoconstriction in asthmatics

Front 32

Nadolol

Back 32

β1 β2 antagonist; trx HTN, long halflife, no CNS effects

Front 33

Timolol

Back 33

β1 β2 antagonist; trx Glaucoma and high IOP

Front 34

Pindolol

Back 34

β1 antagonist; HTN

Front 35

Labetalol

Back 35

β1 β2 and α1 antagonist; HTN

Front 36

Carvedilol

Back 36

β1 β2 and α1 antagonist; Post-MI

Front 37

Metoprolol

Back 37

β1, some β2 antagonist; HTN and angina

Front 38

Atenolol

Back 38

β1 antagonist; HTN and angina; longer acting, no CNS effect

Front 39

Esmolol

Back 39

β1 antagonist; Cardiac dysrhythmias; short acting

Front 40

Acetylcholine

Back 40

M and N agonist; not used clinically

Front 41

Carbachol

Back 41

M and N agonist – glaucoma, counteract atropine

Front 42

Bethanechol

Back 42

Mus agonist; tx urinary retention

Front 43

Pilocarpine

Back 43

Mus agonist; tx glaucoma

Front 44

Methacholine

Back 44

Mus agonist; dx of bronchial asthma

Front 45

Succinylcholine

Back 45

Nic agonist

Front 46

Edrophonium

Back 46

ChE Inhibitor Myasthenia Gravis

Front 47

Neostigmine

Back 47

ChE Inhibitor MG

Front 48

Physostigmine

Back 48

ChE Inhibitor Glaucoma

Front 49

Pyridostigmine

Back 49

ChE Inhibitor MG, long acting

Front 50

Malathion

Back 50

ChE Inhibitor Irr - pesticide

Front 51

Parathion

Back 51

ChE Inhibitor Irr - pesticide

Front 52

Echothiophate

Back 52

ChE Inhibitor Irr - Glaucoma

Front 53

Tacrine

Back 53

ChE Inhibitor Alz

Front 54

Donepezil

Back 54

ChE Inhibitor Alz

Front 55

Rivastigmine

Back 55

ChE Inhibitor Alz

Front 56

Atropine

Back 56

Mus antagonist; tx incontinence; CNS stimulator

Front 57

Scopolamine

Back 57

Mus antagonist; tx seasickness, vomiting, nausea

Front 58

Cyclopentolate

Back 58

Mus antagonist; shortacting mydriasis

Front 59

Tropicamide

Back 59

Mus antagonist, shortacting mydriasis

Front 60

Ipratropium bromide

Back 60

Mus antagonist; treats asthma by shutting down vagus

Front 61

Curare

Back 61

Nic antagonist Surgical anesthesia; no CNS

Front 62

Mivacurium

Back 62

Nic antagonist Settling fractures, short acting

Front 63

Trimethaphan

Back 63

Nic antagonist Controlled hypotension

Front 64

Pilocarpine + Carbachol

Back 64

Mus agonist

Front 65

Physostigmine + Echothiophate

Back 65

Mus agonist – increased outflow

Front 66

Timolol

Back 66

β2 (and beta1) antagonist – decreased humor production

Front 67

Epinephrine + Dipivefrin

Back 67

α1 α2 agonist – vasoconstriction, reduced production of aqueous humor

Front 68

Diazepam

Back 68

+GABA; sedation

Front 69

Benzodiazepines

Back 69

+GABA; sedation

Front 70

Baclofen

Back 70

+GABA; less sedative

Front 71

Dantrolene

Back 71

Blocks Ca release