Pharm #4

Front 1

Aminoglycosides
(Antibiotics)
Adverse Effects

Back 1

Monitor for tinnitus and hearing loss

Front 2

Aminoglycosides
(Antibiotics)
Nursing dx:

Back 2

Risk for injury (hearing loss)

Front 3

Antitubercular drugs

Back 3

multiple drugs used to reduce the chances of MDR and because of MDR

Front 4

Antitubercular drugs: Isoniazid (INH)

Back 4

Contraindicated with liver disease

Front 5

Antitubercular drugs: Nursing Education

Back 5

Therapy may last for up to 24 months

Front 6

Antitubercular drugs: Theraputic response

Back 6

Theraputic response is noted because there is a decrease in symptoms of tuberculosis along with improved chest x-ray and sputum cultures.

Front 7

Antitubercular drugs: Monitor for adverse effects

Back 7

CALL MD IMMEDIATELY if adverse effects noted:
Fatugue, nausea, vomiting, numbness and tingling of the extremieites, fever, low of appetite, depression, jaundice

Front 8

Amphotericin B (Anit Fungal)
Adverse Effects

Back 8

Tingling, numbness in hands and feet. Discontinue immediatley

Front 9

Antifungal Drugs: Contraindications

Back 9

Liver failure
Kidney failure

Front 10

Nystatin given as an oral lozenge or troche:

Back 10

should be slowly and completely dissolved in the mouth (not chewed or swalloed whole)

Front 11

NSAIDs: Large and chemically diverse group of drugs with the following properties

Back 11

Analgesic
Antiinflammatory
Antipyretic
Antirheumatic

Front 12

Salicylate Toxicity (Asprin):
Adults

Back 12

Adults: Tinnitus and hearling loss

Front 13

Salicylate Toxicity (Asprin):
Children

Back 13

hyperventilation and CNS effects- behavioral changes

Front 14

Salicylate Toxicity (Asprin):

Back 14

Metabotic acidosis and respiratory alkalosis may be present

Front 15

Tylenol should be used

Back 15

to reduce fevers in children vs Asprin

Front 16

NSAIDs: Adverse Effects

Back 16

Contraindicated in patients with renal disease

Front 17

NSAIDs: Interactions

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Anticoagulants
Aspirin
Corticosteroids and other ulcerogenic drugs
Protien bound drugs
Diuretics and ACE inhibitors

Front 18

Allopurinol (Zyloprim)

Back 18

Used to reduce production of uric acid

Front 19

Muromonab-CD3

Back 19

is the ONLY drug indicated for reversal of organ rejection once its contraindicated in the presence of fluid overload

Front 20

Azathioprine (Imuran)

Back 20

Leukopenia is an expected adverse effect, as is thrombocytopenia and hepatotoxicity

Front 21

Immunosuppressants: Monitoring

Back 21

Monitor WBC counts throughout therapy; if the count drops below 3000/mm discontinue the drug, but only after contacting the physician

Front 22

Immunosuppressants: Oral dosing

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Oral forms are used when possible to decrease the risk of infection that may occure with parenteral injections

Front 23

Active Immunization:
AKA artifical active immunity

Back 23

The body is exposed to a relatively harmless form of an antigen
The immune system is stimulated and 'remembers' this antigen if subsequent exposures occur
Do not cause a full-blown infection
Contraindicated in patients with active infections, patients who are immunosuppresed, those receiving cancer chemotherapy, patients with AIDS

Front 24

Antivenins

Back 24

Pit viper, coral snake, Black widow spider

Front 25

Give HBV (against Hep B)

Back 25

after a needle stick

Front 26

Anthrax

Back 26

can cause infection via 3 routes; cutaneous, GI, and inhalation

Front 27

Sarcomas

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malignant tumors that arise from connective tissues found in bone, cartilage, muscle, blood, lymphatic, and vascular tissues

Front 28

Chemotherapy

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Combination of drugs is usually more effective than single-drug therapy

Front 29

Antimetabolites: Methotrexate

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NSAIDs can lead to toxicity

Front 30

Antimetabolites: Methotrexate: Leucovorin "rescue"

Back 30

when severe bone marrow suppression occurs

Front 31

Implement measures to monitor for and prevent infection in patients with neutropenia or leucopenia-

Back 31

Early sign of infection is fever

Front 32

Chemotherapy: Nausea

Back 32

Anticipate nausea and vomitting, and implement measures to reduce.
antiemetics often work better if given 30-60 minutes before

Front 33

Chemotherapy: Stools

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Report black tarry stools

Front 34

Chemotherapy: Extravasation

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If suspected, stop the IV infusion immediately but do not remove the IV tube
If possible aspirate remianing drug or blood from the tube

Front 35

Chemotherapy: routes

Back 35

Some antidotes are not given through the IV catheter

Front 36

Special concerns if chemptherapy liquid spills-

Back 36

use a spill kit if any spilled

Front 37

Assess baseline blood counts before giving antineoplastic drugs-NADIR

Back 37

lowest level of neutrophils reached during therapy

Front 38

Alkylating drugs: Stomatitis

Back 38

examine mouth daily for bleeding, painful areas, and ulcerations

Front 39

Chemotherapy: Patients may experience GI adverse effects

Back 39

to counter act these an appropriate goal would be to maintain a diet of frequent feedings with a nutrition supplement as a snack

Front 40

Monitor for oncologic emergencies

Back 40

Infections and Bleeding

Front 41

Erthropoietic drugs

Back 41

formation of red blood cells
epoetin alfa (Epogen, Procrit)
darbepoetin alfa (Aranesp)

Front 42

Colony-stimulating factors (CSFs)

Back 42

interfere directly with the action of chemotherapy. If needed give 24 hours after chemo has been completed