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14 Cards in this Set
- Front
- Back
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2 categories of cholinesterase inhibitors
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reversible
irreversible |
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Neostigmine
Class: Indications |
Reversible cholinesterase inhibitor
Myasthenia Gravis |
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Agonists
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promotes Ach
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Antagonist
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Block
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CholinesterASE Inhibitors
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Prevent the enzyme from activation.
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Cholinesterase has _____ therapeutic use
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limited
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Neostigmine causes muscarinic responses that are the same as __________ drugs
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cholinergic
Increased gland secretion increased tone motility decreased HR bronchial constriction, miosis for near vision |
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Neostigmine is ________ absorbed orally and ______ cross the BB Barrier
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poorly, cannot
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Adverse Effects of Cholinesterase Inhibitors
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Excessive Muscarinic Stim- excess secretion, increased tone, brady, sweat
Neuro Muscular Block- can paralyze resp muscles |
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Toxicity of Cholinesterase Inhibitors (also called cholinergic crisis
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resp depression, excessive muscarinic stim
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Treatment for Cholinesterase inhibition or cholinergic crisis
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ATROPINE, VENT
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Irriversible cholinesterase inhibitors are primarily
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insectiside
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Irriversible Cholinesterase inhibitors have 1 indication
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glaucoma
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Physostigmine is the antidote to poisioning by muscarinic
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antagonists
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