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33 Cards in this Set
- Front
- Back
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Vitamin K dependent anticoagulant |
Warfarin (PT)
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Warfarin is contraindicated in
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Pregnancy
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Anticoagulant of choice in pregnancy
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Heparin
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Heparin (PTT) increases activity of
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Antithrombin 3
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Route of administration of warfarin
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Oral
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Routes of administration of heparin
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IV and IM (only LMW)
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SE of both warfarin and heparin
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Bleeding
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SE of heparin
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Heparin induced thrombocytopenia (HIT)
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Alternative anticoagulant used if HIT develops
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Lepirudin
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Antidote to reverse actions of warfarin
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Vitamin K or fresh frozen plasma
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Antidote to reverse actions of heparin
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Protamine sulfate
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MOA of aspirin
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Irreversibly blocking cyclooxygenase
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Agent used to treat MI and to reduce incidence of subsequent MI
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Aspirin, metoprolol
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SE of Aspirin
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GI bleeding
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Antiplatelet drug reserved for patients allergic to aspirin
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Ticlopidine
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SE for ticlopidine
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Neutropenia and agranulocytosis
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Effective in preventing TIA's
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Clopidogrel and ticlopidine
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Prevents thrombosis in patients with artificial heart valve
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Dipyridamole
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Block glycoprotein IIb/IIIa involved in platelet crosslinking
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Abciximab, tirofiban and eptifibatide
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MOA of thrombolytics
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Degradation of fibrin clots and are administered IV
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Thrombolytics are used for
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Pulmonary embolism and DVT
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Thrombolytic that can cause allergic reaction
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Streptokinase
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Thrombolytic used for acute MI and ischemic (non-hemorrhagic) CVA
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Tissue plasmin activator
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SE of tPA
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Cerebral hemorrhage
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Antidote for thrombolytics
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Aminocaproic acid
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Agent to treat hypochromic microcytic anemias
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Ferrous sulfate
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Chelating agent used in acute iron toxicity
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Deferoxamine
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Agent for pernicious anemia
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Cyanocobalamin (Vit B12)
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Agent used for neurological deficits in megaloblastic anemia
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Vitamin B12
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Agent used for megaloblastic anemia (but does NOT reverse neurologic symptoms) and decrease neural tube defects during pregnancy
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Folic acid
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Agent used for anemias associated with renal failure
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Erythropoietin
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Agent used neutropenia especially after chemotherapy
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G-CSF (filgrastim) and GM-CSF (sargramostim)
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Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy
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Interleukin 11 (oprelvekin)
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