Phar 740 Antibiotic Review

Front 1

penicillins, cephalosporins, carbepenems, and monobactams are what types of cell wall agents

Back 1

beta lactams

Front 2

What is the MOA of beta lactams

Back 2

bind to penicillin binding proteins - leads to cell lysis and death

Front 3

pen VK and pen G are what type of penicillin?

Back 3

natural

Front 4

these drugs fall under penicillinase-resistant penicillins

Back 4

nafcillin
oxacillin
dicloxacillin

Front 5

amoxacillin and ampicillin are what type of penicillin?

Back 5

aminopenicillin

Front 6

these drugs are extended spectrum penicillin

Back 6

piperacillin
ticarcillin

Front 7

What is the MOA of beta-lactamase inhibitors

Back 7

prevent hydrolytic action
binds directly to penicillin-binding proteins

Front 8

What drugs fall under beta-lactamase inhibitors

Back 8

amoxicillin/clavulanic
ampicillin/sulbactam
piperacillin/tazobactam
ticarcillin/clavulanate

Front 9

these drugs are carbapenems

Back 9

imipenem/cilastatin
meropenem
doripenem
ertapenem

Front 10

This drug is a monobactam

Back 10

aztreonam

Front 11

this drug is a glycopeptide

Back 11

vancomycin

Front 12

This drug is a cyclic glycopeptide

Back 12

daptomycin

Front 13

what is the MOA of cyclic glycopeptide

Back 13

binds to cell membrane to cause rapid depolarization to inhibit DNA, RNA, and protein synthesis

Front 14

this drug damages cell membrane to allow leakage of cell contents

Back 14

polymixin B and E

Front 15

This class of drugs inhibits bacterial DNA topoisomerase and gyrase, promoting DNA breakage

Back 15

fluoroquinolone

Front 16

ciprofloxacin
levofloxacin
moxifloxacin
gemifloxacin
ofloxacin
What is the class

Back 16

fluoroquinolones

Front 17

this class of drugs causes loss of DNA helical structure and strand breakage

Back 17

nitroimidazole

Front 18

this drug is a nitroimidazole

Back 18

metronidazole

Front 19

This class of drug inhibits the beta subunit of DNA-dependent RNA polymerase

Back 19

rifamycins

Front 20

This drug is a rifamycin

Back 20

rifampin

Front 21

This class of drug is a folate antagonist

Back 21

folic acid inhibitors

Front 22

this drug is a folic acid inhibitor

Back 22

bactrim

Front 23

These class of drugs are bacteriostatic

Back 23

protein inhibitors (except aminoglycosides)

Front 24

These agents inhibit 30S protein

Back 24

tetracycline
glycylcylines

Front 25

These agents inhibit 30S and 50S protein

Back 25

aminoglycosides

Front 26

these agents inhibit 50S protein

Back 26

macrolides
lincosamides
streptogrammins
oxazolidinones

Front 27

What class of drug does doxycyline and minocycline fall under?

Back 27

tetracyclines

Front 28

What class of drugs do tigecycline fall under

Back 28

glycylcyline

Front 29

What drugs fall under macrolides

Back 29

erythromycin
azithromycin
clarithromycin

Front 30

Clindamycin falls under what class of drugs

Back 30

lincosamide

Front 31

Quinupristin falls under what class of protein inhibitors?

Back 31

streptogrammin

Front 32

macrobid and macrodantin falls under what class of drugs

Back 32

nitrofurantoin

Front 33

This class of drugs are reduced to active intermediates by flavoproteins - active intermediates inactivate or damage ribosomal proteins, DNA, and RNA

Back 33

nitrofurantoin