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33 Cards in this Set

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  • Back
penicillins, cephalosporins, carbepenems, and monobactams are what types of cell wall agents
beta lactams
What is the MOA of beta lactams
bind to penicillin binding proteins - leads to cell lysis and death
pen VK and pen G are what type of penicillin?
natural
these drugs fall under penicillinase-resistant penicillins
nafcillin
oxacillin
dicloxacillin
amoxacillin and ampicillin are what type of penicillin?
aminopenicillin
these drugs are extended spectrum penicillin
piperacillin
ticarcillin
What is the MOA of beta-lactamase inhibitors
prevent hydrolytic action
binds directly to penicillin-binding proteins
What drugs fall under beta-lactamase inhibitors
amoxicillin/clavulanic
ampicillin/sulbactam
piperacillin/tazobactam
ticarcillin/clavulanate
these drugs are carbapenems
imipenem/cilastatin
meropenem
doripenem
ertapenem
This drug is a monobactam
aztreonam
this drug is a glycopeptide
vancomycin
This drug is a cyclic glycopeptide
daptomycin
what is the MOA of cyclic glycopeptide
binds to cell membrane to cause rapid depolarization to inhibit DNA, RNA, and protein synthesis
this drug damages cell membrane to allow leakage of cell contents
polymixin B and E
This class of drugs inhibits bacterial DNA topoisomerase and gyrase, promoting DNA breakage
fluoroquinolone
ciprofloxacin
levofloxacin
moxifloxacin
gemifloxacin
ofloxacin
What is the class
fluoroquinolones
this class of drugs causes loss of DNA helical structure and strand breakage
nitroimidazole
this drug is a nitroimidazole
metronidazole
This class of drug inhibits the beta subunit of DNA-dependent RNA polymerase
rifamycins
This drug is a rifamycin
rifampin
This class of drug is a folate antagonist
folic acid inhibitors
this drug is a folic acid inhibitor
bactrim
These class of drugs are bacteriostatic
protein inhibitors (except aminoglycosides)
These agents inhibit 30S protein
tetracycline
glycylcylines
These agents inhibit 30S and 50S protein
aminoglycosides
these agents inhibit 50S protein
macrolides
lincosamides
streptogrammins
oxazolidinones
What class of drug does doxycyline and minocycline fall under?
tetracyclines
What class of drugs do tigecycline fall under
glycylcyline
What drugs fall under macrolides
erythromycin
azithromycin
clarithromycin
Clindamycin falls under what class of drugs
lincosamide
Quinupristin falls under what class of protein inhibitors?
streptogrammin
macrobid and macrodantin falls under what class of drugs
nitrofurantoin
This class of drugs are reduced to active intermediates by flavoproteins - active intermediates inactivate or damage ribosomal proteins, DNA, and RNA
nitrofurantoin