Phar 640 Skeletal Muscle Relaxant

Front 1

What type of agents improve muscle hypertonicity, involuntary jerks, and the following medical conditions:
multiple sclerosis
spinal cord injuries
cerebral palsy

Back 1

antispaticity agents

Front 2

What type of agents are used to treat muscoloskeletal conditons?

Back 2

antispasmodic agents

Front 3

What type of agents are baclofen and dantrolene

a. antispacticity
b. antispasmodic
c. combo

Back 3

a. antispacticity

Front 4

What agents are cyclobenzaprine, carisoprodol, metaxalone, chlorzoxazone, methocarbamol, and orphenadrine?

a. antispacticity
b. antispasmodic
c. combo

Back 4

b. antispasmodic

Front 5

What type of agents are benzos and tizanidine?

a. antispacticity
b. antispasmodic
c. combo

Back 5

c. combo

Front 6

These drugs are indicated to relieve discomfort caused by acute painful musculorskeletal conditions

Back 6

carisoprodol
chlorzoxazone
metaxalone
methocarbamol
orphenadrine

Front 7

This drug is indicated to releive discomfort caused by acute painful musculoskeletal conditions and demonstrates analgesic function

Back 7

orphenadrine

Front 8

These drugs are indicated to relieve discomfort caused by acute painful musculoskeletal conditions and have sedative properties

Back 8

carisoprodol
chlorzoxazone
metaxolone
methocarbamol

Front 9

These drugs are indicated for musculoskeletal conditions related to muscle spasm, pain, tenderness and movement restriction

Back 9

cyclobenzaprine
amrix (cyclobenzaprine ER)

Front 10

What is the MOA of cyclobenzaprine?

Back 10

acts in spinal chord and brain stem

Front 11

These drugs are indicated for spasticity associated with neuron disorders

Back 11

baclofen
dantrolene
tizanidine

Front 12

What drug am I:
a structural analog of GABA
block spinal reflexes
indicated for spasticity associated with neuron disorders

Back 12

baclofen

Front 13

What drug am I:
distrub calcium ion release from sarcoplasmic reticulum and work directly on skeletal muscle
indicated for spasticity associated with neuron disorders

Back 13

dantrolene

Front 14

What drug am I:
stimulate alpha 2 receptor and inhibit motor neurons
indicated for spasticity associated with neuron disorders

Back 14

tizanidine

Front 15

What is the first line treatment for low back pain?

Back 15

apap
nsaids

Front 16

skeletal muscle relaxant are reserved as _________ treatment options for short term relief of acute low back pain.

Back 16

alternative

Front 17

What are the central nervous system adverse effects of skeletal muscle relaxants?

Back 17

drowsiness
dizziness
headache
confusion

Front 18

cyclobenzaprine, carisoprodol, tizanidine and orphenadrine have been shown to be effective for _____ weeks

Back 18

2-4 weeks

Front 19

Which have a statistically significant decrease in muscle spasm and tenderness, cyclobenzaprine + naproxen or naproxen alone?

Back 19

cyclobenzaprine + naproxen

Front 20

Is tizandine and analgesics more effective together or alone at decreasing muscle spasm and providing pain relief?

Back 20

together

Front 21

True or False: combination thearpy does not improve recovery time

Back 21

False

Front 22

what are the goals of skeletal muscle relaxant treatment?

Back 22

improve functional status
manage muscle pain

Front 23

These drugs should be avoided in the elderly

Back 23

diazepam
orphenadrine
methocarbamol
cyclobenzaprine

Front 24

These drugs should be avoided in patiens with arrhythmias

Back 24

cyclobenzaprine
tizanidine

Front 25

These drugs should be avoided in children <12

Back 25

carisoprodol
metaxalone

Front 26

These drugs should be avoided in patients with GI disturbances

Back 26

orphenadrine
chlorzoxazone
dantrolene

Front 27

What is the most commonly used benzo?

Back 27

diazepam

Front 28

Why should diazepam be avoided in the elderly?

Back 28

long half life upto 100 hours

Front 29

These drugs should be avoided in patients with myathenia gravis

Back 29

orphenadrine
methocarbamol

Front 30

These drugs should be avoided in patients with cardiospasm

Back 30

orphenadrine

Front 31

These drugs should be avoided in pts with liver impairment

Back 31

chlorzoxazone

Front 32

these drugs should be avoided in pts with anemia

Back 32

metaxalone
orphenadrine

Front 33

these drugs should be avoided in pts with glaucoma

Back 33

orphenadrine
cyclobenzaprine

Front 34

these drugs should be avoided in pts with seizure history

Back 34

baclofen
carisoprodol

Front 35

these drugs should be avoided in pts with abuse history

Back 35

diazepam
methocarbamol

Front 36

these drugs should be avoided in renal failure pts

Back 36

methocarbamol
metaxolone

Front 37

these drugs require renal dose adjustment

Back 37

baclofen
tizanidine - CrCl < 25

Front 38

these drugs should be avoided in renal impairment

Back 38

diazepam

Front 39

These drugs can cause hepatotoxicity

Back 39

chlorzoxazone
tizanidine
dantrolene - dose dependent

Front 40

these drugs should be avoided in renal impairment

Back 40

diazepam
metaxalone
chlorzoxazone
carisoprololq

Front 41

This drug has a black box warning about symptomatic fatal or non fatal hepatitis

Back 41

dantrolene

Front 42

these drugs can increase AST levels and alkaline phosphate

Back 42

baclofen
tizanidine
dantrolene
metaxalone

Front 43

these drugs require LFT testing

Back 43

tizanidine
dantrolene
metaxalone

Front 44

these drugs requires tapering when discontinuing therapy

Back 44

*baclofen
*carisoprodol
metaxalone
tizanidine

Front 45

These drugs can cause seizures if it is not tapered when discontinuing

Back 45

baclofen
carisoprodol

Front 46

These drugs can cause urine discoloration

Back 46

chlorzoxazone
methocarbamol

Front 47

What schedule drug in carisoprodol?

Back 47

4

Front 48

What drug am I:
can cause idiosyncratic or allergy type reaction after first dose
metabolized to meprobamate

Back 48

carisoprodol