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73 Cards in this Set

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Loratadine
Second generation H1 blocker like fexofenadine
Certizine
Second generation H1 blocker like fexofenadine
Metoclopramide
Dopamine blocker that is an antiemetic much like prochlorperazine.
Isosorbid dinitrate
Long acting oral form of nitroglycerin
Enalapril
ACE inhibitor much like Captopril
Diltiazem
CCB like verpamil but causes less coronary vasodilation and less negative intropy
Nicardipine
Second generation dihydropyridine CCB which shows great vascular smooth muscle selectivity. Derviative of nifedipine.
Amlodipine
Second generation dihydropyridine CCB which shows great vascular smooth muscle selectivity. Derviative of nifedipine.
Felodipine
Second generation dihydropyridine CCB which shows great vascular smooth muscle selectivity. Derviative of nifedipine.
Mountelukast
Leukotrine receptor antagonist
Zileuton
5-LO blocker
Latanoprost
PGF derivative that is used in treating glaucoma
Misoprostol
PGE derivative used in stimulating gastric secretions and abortion
Chlorpheniramine
H1 blocker that is lipophilic like diphenhydramine
Cyproheptadine
H1 blocker that is lipophilic like diphenhydramine
Dimenhrydrinate
H1 blocker that is lipophilic like diphenhydramine
Guanethidine
Binds to storage vesicles and inhibits the release of NE.
Guanadrel
Binds to storage vesicles and inhibits the release of NE.
Reserpine
Binds to NT storage vesicles and prevents catecholamines from going into them.
Pseudephedrine
Less potent mixed acting sympathomimetic
Scopolamine
Antimuscarinic used prophylactically for sea sickness
Cyclopentolate
Antimuscarinic for mydriasis and cycloplegia
Tropicamide
Antimuscarinic for mydriasis and cycloplegia
Homatropine
Antimuscarinic for mydriasis and cycloplegia
Physostigmine
Cholinesterase inhibitor that can cross the blood brain barrier - antidote for anticholinergic delirium
Phenoxybenzamine
non-selective alpha blocker and blocks the action of seratonin, histamine and ACh - IRREVERSIBLE binding
Dexmedetomidine
Alpha 2 agonist
Carbachol
Quaternary choline ester that is a non-selective cholinomimetic
Oxymetazoline
Topical alpha-1 agonist
Nadolol
Once a day non-selective beta-blocker - 1st generation
Pindolol
Non-selective beta-blocker with intrinsic sympathomimetic activity - 1st generation
Labetalol
Beta blockers with alpha blocking qualities as well - 1st generation
Carvedilol
Beta blockers with alpha blocking qualities as well - 1st generation
Methyphenidate
indirect sympathomimetic - Ritalin
Esmolol
Short half-life second generation beta 1-blocker
Atenolol
Beta-1 blocker with a longer half-life that metoprolol - 2nd generation
Acebutolol
Beta 1 blocker with intrinsic sympathomemtic activity - 2nd generation
Betaxolol
Beta-1 selective blocker - once a day
Terazosin
Long acting alpha-1 blocker
Doxazosin
Long acting alpha-1 blocker
Tamsulosin
Selective for Alpha-1A
Yohimbine
Alpha 2 blocker - antidote for clonidine poisioning
Tolazoline
Alpha blocker
Terbutaline
Beta-2 selective bronchodilator - status asthmaticus and stopping premature labor
Salmeterol
Beta-2 agonist with long duration of action
Pralidoxime
Cholinesterase regenerator
Donepezil
Reversible Cholinesterase inhibitor for AD
Rivastigmine
Reversible Cholinesterase inhibitor for AD
Galanthamine
Reversible Cholinesterase inhibitor for AD
Flucticasone
Glucocorticoid nasal spray
Two cytokines mast cells produce.
1. IL4
2. TNF
Skin mast cells are activated by what?
Opiates
What is the triple response and what are its mediators?
1. Flush - H1
2. Flare - Substance P
3. Wheal - H1
Antihistamines have no effect on what?
Late symptoms
Antihistamines have what sort of organic chemistry specificity?
Chiral specificity
Azelastine
Topical antihistamine that tastes bitter
Olopatadine
Ocular antihistamine (2x day)
Levocabastine
Ocular antihistamine (4x day)
What is the triple response of seratonin?
1. Hypotension - chemoreceptor (Bezold Jarisch)
2. Hypertension - vasoconstriction
3. Hypotension - NO
What is the name for seratonin toxicity?
Carcinoid syndrome due to tumor
How do you tets for carcinoid tumor?
1. Chromagranin A
2. 5 Hydroxy indole
Cyproheptadine
H1 Antagonist
Samter's Triad
1. Asprin allergy
2. Nasal Polyps
3. Asthma

Due to excessive LTs
What is Flapper?
5-LO activator
Zeulitin (Zyflo)
Flapper antagonist
Adenosine
Treats supraventricular arrhythmias
Mangensium sulfate
Treats refractory vent. tachyarrhythmias
Sotalol
Class III and Class II actions for both supra and ventricular arrhythmias
Pepstatin
Acid protease inhibitor
Enalkiren
Angiotensinogen analogue
Teprotide
1st identified ACE inhibitor that was derived from snake venom. Had to be administered IV and fast
Saralasin
IV administered ATII Receptor blocker - peptide
Pirenzepine
M1 agonist activity on the cilliary body sphincter