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27 Cards in this Set
- Front
- Back
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frequent MC =
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polymenorrha
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infrequent MC =
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oligomenorrhea
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high volume of menstrual flow =
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hypermenorrhea
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prolonged menstrual flow =
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menorrhagia
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polymenorrhea, cycles less than
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21 days
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therapy of polymenorrhea
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- Progestines during luteal phase of cycle (normoestrogenic disorders)
- Progestines+estrogenes (hypoestrogenic disorders) |
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oligomenorrhea, cycles over
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35 days
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therapy of oligomenorrhea
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- No therapy (normoestrogenic disorders)
- Progestines during luteal phase of cycle (normoestrogenic disorders) - Progestines+estrogenes (hypoestrogenic disorders) - Induction of ovulation (infertility) |
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causal therapy of primary amenorrhea
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Progestines+estrogenes (hypoestrogenic disorders)
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therapy of secondary amenorrhea
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Therapy – normoprolactinemic and normoestrogenic
Progestogenes Ovulation induction |
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DUB =
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dysfunctional uterine bleeding
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hormonal therapy of DUB
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Estrogens (E)
Progestins (P) E/P Danazol GnRh - a SERM |
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non-hormonal therapy of DUB
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Nonsteroidal antirevmatics
Mefenamic acid Ethamsylate Antifibrinolytics EAC Tranexamic acid |
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surgical therapy of DUB - Endometrial ablation – hysteroscopical
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Roller ball ablation (25-60%)
Transcervical resection (26-40%) Laser ablation (37%) |
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surgical therapy of DUB - Endometrial ablation – non-hysteroscopical
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RFEA – Radio Frequency Endometrial Ablation (41%)
TBEA – Thermal Balloon Endometrial Ablation (48%) MWEA – MPicrowave Endometrial Ablation (61%) |
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posttraumatuc hypomenorrhea
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Aschermanns syndrome
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therapy of Aschermanns syndrome
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Hysteroskopy – lysis of adhaesions – IUD - estrogens
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theray alternatives for dysmenorrhea
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Secondary dysmenorrhoea – causative
Primary dysmenorrhoea – combined hormonal contraception effectivity – 90% Progestogens contraception – long acting LNG-IUS Non-steroidal anti-inflammatory drugs (NSAIDs) - 2-3 days before menstrual bleeding - Continue to the 2.day of bleeding |
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premenstrual syndrome - therapy
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Diet regime – restriction of coffein, alcohol, salt, glycids
Aerobic exercise Psychological consultation Symptomatic treatment according to prevailing syndrome Combined oral contraception (drospirenon) Agnus castus Non-steroidal anti-inflammatory drugs SIRS - fluoxetin |
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estrogen therapy of DUB
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CEE - 2.5 mg p.o. a 6 h. or 25 mg i.v. a 4 h. for 48 h.
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progestin therapy of DUB
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- MPA 10 mg/d for 10-12 d.
- NES 10-15 mg/d 10 d. - LNG-IUS |
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E/P therapy of DUB
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Combined orla contraception
- Acute DUB - 70-140 μg/d - Prevention – usual pattern, long cycle pattern, continual Adolescent gynecology - acute DUB - Progesterone 10 mg/ Estradioldipropionate 2 mg i.m. |
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GnRH agonists as pharmacotherapy of DUB
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- goserelin (Zoladex Depot 3,75 mg)
- tryptorelin (Decapeptyl Depot 4,12 mg, Dipherelin 4,39 mg) - leuprorelin (Lucrin Depot 3,75 mg) |
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pharma therapy of DUB - Nonsteroidal antirevmatics
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Naproxen (Aleve tbl.220 mg, Apo-naproxen tbl. 250 mg, Nalgesin tbl. 270 mg)
Mefenamic acid (Nimesulid tbl. 100 mg) |
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pharma therapy of DUB - antifibrinolytics
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Tranexamic acid (Exacyl p.o. tbl. 500 mg , oral solution 10ml/1000 mg a venous injection 5 ml/500mg)
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effectiveness of pharmacotherapy of DUB
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Progestins - 21 day cycle 30-90%
Combined oral contraception 43% Danazol 50-80% LNG IUS 74-97% DMPA 50-66% GnRH agonists >90% |
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non-hormonal pharmacotherapy of DUB
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Non-steroidal antirevmatics 20-50% ?
Tranexamic acid 47-54% Etamsylate 13%? |
