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5 Cards in this Set
- Front
- Back
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What is peripheral arterial disease
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Vascular insufficiencies caused by noncoronary arteries secondary to atherosclerotic occlussions
Symptoms: Leg or hip pain, cold legs and feet, changes in skin color, pain that is reduced upon resting, numbness or tingling |
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What risk factors exist for PAD
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Age > 50
Cigarette smoker Diabetes Cholesterol Family hx HTN Male sex Homocysteine elevated |
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What is the drug treatment for PAD
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1) Smoking cessation - most important!
2) Statins - goal LDL <70 3) Fibric acid agents - used with high TG 4) Antihypertensives - goal BP of less than 140/90, <130 if has CKD or DM 5) Antiplatelet agents for all patients. Aspirin 75-325mg |
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How do you treat claudication
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1) Cilostazol (Pletal)
Phosphodiesterase inhibitor that is vasodilatory and antiplatelet Avoid use in HF 2) Pentoxyifylline (Trentall) Reduces blood and plasma viscosity, inhibits neutrophil adhesion and activation Second line agent |
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How do you treat critical limb ischemia
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1) IV pentoxyifylline
2) Oral vasodilator prostaglandins 3) Endovascular treatment |
