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182 Cards in this Set

  • Front
  • Back
What is the difference between fever and hyperthermia?
Hyperthermia occurs when normal thermoregulation fails, resulting in an unregulated rise in core temperature.
True/False. The newborn displays a decreased inflammatory response to invading organisms.
True. The newborn displays a decreased inflammatory response to invading organisms, contributing to an increased risk for infection (p. 451).
True/False. Cellular immunity is present at birth.
True (p. 451).
True/False. Studies have shown that ibuprofen is superior in reducing fever faster and lasts longer than acetaminophen.
True. (p. 461)
Sepsis is most common in what age group?
Neonates and young infants, due to their immature immune system, inability to localize infections, and lack of IgM which is necessary to protect against bacterial infections. (p. 462)
___ is an infection resulting from group A streptococci.
Scarlet Fever (p. 465)
True/False. A child infected with scarlet fever is no longer contagious 24 hours after the initiation of appropriate antimicrobial therapy.
True (p. 465)
A 6-year-old patient in a clinic has a fever of 101F, nausea and vomiting, sore throat, and what appears to be a sunburn on his face, trunk, and extremities. Upon palpation, you note it has a sandpapery consistency. What do you suspect he has?
A) CMRSA
B) Diptheria
C) Mumps
D) Scarlet fever
D) Scarlet fever (p. 465)
This is the treatment of choice for scarlet fever.
Penicillin V (p. 465)
In ___, a pseudomembrane forms over the pharynx, uvula, tonsils, and soft palate.
Diptheria (p. 465)
In patients with diptheria, what is your primary concern?
A) Consistent dosing with antipyretics, as they can spike a fever as high as 105F.
B) Strict I&O, as the bacteria responsible can cause glomerulonephritis
C) Airway management, as swallowing may become difficult as the pseudomembrane forms
D) Seizure precautions, as acute CNS infection can result in swelling of the brain and meninges
C) Airway management, as swallowing may become difficult as the pseudomembrane forms (p. 466)
The highest incidence of pertussis is seen in children younger than how old?
1 year of age. Children younger than 6 months of age are at greatest risk for severe disease and death (p. 466)
Which form of tetanus is the most common worldwide?
Neonatal tetanus
___, a contagious disease caused by paramyxovirus, is characterized by fever and parotitis.
Mumps (p. 474)
Current recommendations include first mumps immunization between ___ and ___ months of age.
12 and 15 months of age, followed by a second vaccine between 4 and 6 years of age (p. 474).
True/False. Once symptoms of rabies have developed, the prognosis is poor.
True. (p. 475)
___ is a cell-mediated response to an antigenic substance exposure.
Contact dermatitis (p. 890)
True/False. A child with poison oak contact dermatitis is not contagious.
True. (p. 891). Contact dermatitis is not contagious and does not spread either to other parts of the affected child's skin or to other people. Scratching does not spread the rash, but it may cause skin damage or secondary infection.
True/False. Latex or rubber gloves are an effective barrier against offending plants such as poison oak.
False. Vinyl gloves are an effective barrier (p. 891).
___ is the most severe form of erythema multiforme.
Stevens-Johnson syndrome (p. 892). It typically occurs in response to certain medications or to Mycoplasma infection.
True/False. Erythema multiforme often resolves on its own.
True. (p. 892)
Urticaria (hives) is a ___ hypersensitivity reaction caused by an immunologically mediated antigen-antibody response of histamine release from mast cells.
A) Type I
B) Type II
C) Type III
D) Type IV
A) Type I (p. 892)
A mother brings her infant into the clinic for thick, greasy yellow scales on his scalp and in his diaper area. You suspect he has:
A) Psoriasis
B) Seborrhea
C) Acne neonatorum
D) Pressure ulcers
B) Seborrhea (A.k.a. cradle cap)

Seborrhea is a chronic inflammatory dermatitis that may occur on the skin or scalp. It is thought that seborrhea is an inflammatory reaction to the fungus Pityrosporum ovale and is worsened by sebaceous involvement related to maternal hormones in the infant. (p. 893)
Which of the following is an accurate intervention for an infant with cradle cap (select all that apply)?
A) Apply a corticosteroid cream like triamcinolone and cover the infant's head with a shower cap.
B) Wash with lukewarm water and anti-dandruff shampoo (like Head and Shoulders) twice daily until lesions resolve.
C) Apply mineral oil to the scalp, massage it well, then shampoo later.
D) Remove the crusts carefully with tweezers. To reduce infection, apply an antibiotic ointment like Neosporin.
B, C. (p. 894)
Which of the following indicates a need for further instruction in the mother of a child with psoriasis?
A) Exposure to sunlight may promote healing of the skin.
B) The use of warm towels and oil to soak the plaques will help to remove thick plaques.
C) Tar shampoos and skin preparations may be used topically.
D) Very thick lesions may be debrided with hydrogen peroxide.
D. All of the other responses are true. (p. 894)
Acne neonatorum occurs as a response to the presence of maternal androgens. and generally appears between ___ and ___ weeks of age, and lasts up to ___ to ___ months.
Generally appears between 2-4 weeks of age, and lasts up to 4-6 months. (p. 895)
True/False. Girls taking Accutane must be on a pregnancy prevention program.
True. Accutane causes defects in fetal development (p. 896)
The mortality rate from burns is highest in children younger than ___.
6 years of age (p. 897)
Which of the following is NOT a criteria for referral of persons to a burn unit?
A) Burns that involve the face, hands, feet, genitalia, or major joints
B) Carbon monoxide poisoning
C) Inhalation injury
D) Electrical burns or chemical burns
E) Partial thickness burns greater than 10% of total body surface area
B) Carbon monoxide poisoning (p. 898)
In ___ burns, the injury occurs not only to the epidermis, but also to portions of the dermis.
A) Superficial
B) Partial-thickness
C) Deep partial-thickness
D) Full-thickness
B) Partial thickness (p. 898)
These burns may scar and result in changes in nail and hair appearance as well as sebaceous gland function in the affected area.
A) Superficial
B) Partial-thickness
C) Deep partial-thickness
D) Full-thickness
C) Deep partial-thickness (p. 898)
A 4-year old girl arrives in the ER the victim of burn injury from deliberate child abuse. Upon assessing the child's wound, you note significant tissue damage and can visualize a portion of charred subcutaneous fat. His aunt, who brought him in after his mother called her in hysterics, asks you whether this will leave a permanent scar. What should you tell her?
A) In these situations, extensive scarring usually results and skin grafting may be required.
B) Though erythema and ischemic blood flow to the injury may occur for several days, vascularization will resume once swelling has depleted.
C) These burns usually heal within about two weeks and carry a minimal risk of scar formation.
D) With effective debridement and subsequent grafting, there is a good chance her niece will have little scarring.
A. Full-thickness burns result in significant tissue damage as they extend through the epidermis, dermis, and hypodermis. Extensive scarring results, as hair follicles and swear glands are destroyed. Skin grafting may be necessary. (p. 898)
Capillary permeability typically returns to normal between ___ and ___ hours after the burn.
48 and 72 hours (p. 898)
Which of the following is indicated in taking the health history of a child with a burn (select all that apply)?
A) Whether smoke inhalation occurred
B) Was there an associated fall?
C) When was the last tetanus vaccination?
D) What are the child's current medications?
A, B, C, D. (p. 899)
Intentional scald injuries usually yield what type of formation?
"Stocking" or "glove" distribution when the child's extremity is held under very hot water as punishment. (p. 899)
What is the purpose of an EKG in the case of a burn injury?
EKG monitoring is important for the child who has suffered an electrical burn to identify cardiac arrhythmias, which can be noted for up to 72 hours after a burn injury. (p. 900)
True/False. It is important to administer 100% oxygen via nonrebreather mask or bag-valve mask ventilation to all children with severe burns.
True. (p. 901)
High levels of carboxyhemoglobin as a result of smoke inhalation may skew the pulse ox readings how?
High levels of carboxyhemoglobin as a result of smoke inhalation may contribute to falsely high pulse oximetry readings. (p. 901)
Which of the following IV fluids is indicated in a child with a burn injury IN THE FIRST 24 HOURS?
A) NS
B) D5NS
C) D51/2NS
D) LR
D) Lactate Ringers (p. 901)
Which of the following is NOT indicated in the treatment of burns?
A) Soaking the dressing in tap water before removal of gauze
B) Debridement involving the removal of loose skin and eschar
C) Popping blisters when they impede wound care
D) Scrubbing the wound to remove excess eschar and promote healing
D) There is no advantage to scrubbing and only makes the pain more intense.

(p. 902)
Most cases of Lyme disease are seen between what months?
June and August
The incidence of Lyme disease is highest between children ages:
5-10
This is the drug of choice for Lyme disease for children older than 8 years.
Doxycycline. NOTE: Because it can cause permanent discoloration of the teeth, children younger than 8 years should be treated with amoxicillin! (p. 479)
___ is the most severe and frequently reported rickettsial illness in the US.
Rocky Mountain Spotted Fever
A (late/early) sign of RMSF is a rash.
Late. The rash often starts as small, pink, macular, nonitchy, blanchable spots on the wrists, forearms, and ankles. (p. 481)
A ____ is a parasitic intestinal worm.
Helminth (p. 481)
What are some possible drugs/treatments for scabies?
A scabicide, like permethrin or lindane. (p. 483)
When it comes to roundworms, ___ are the major source of infected eggs.
Human feces (p. 484)
True/False. Contact precautions are necessary for patients with roundworms.
False. Standard precautions are sufficient, so long as sanitary disposal of feces is carried out (p. 484).
True/False. An ideal treatment for gonorrhea is Floxin or Cipro in patients under 18.
FALSE. NO Floxin or Cipro if younger than 18 years or pregnant!!! (p. 488)
This test is ideal in diagnosing syphilis.
The Darkfield examination and direct fluorescent antibody tests (p. 490).
Eye color is often determined by what age in infants?
6-12 months of age (p. 553)
20/20 vision is usually achieved by the time the child is how old?
6-7 years old (p.553)
True/False. Warm compresses are indicated in the treatment of conjunctivitis.
True. (p.555)
The usual minimum age for cochlear implants is how old?
12 months. (p.555)
Review question! Blue sclerae that persist beyond a few weeks of life may be an indicator of what?
Osteogenesis imperfect type I, an inherited connective tissue disorder (p. 554).
True/False. Tympanic membrane mobility may be tested with audiometry.
False. Tympanic membrane mobility may be tested with pneumatic otoscopy (p. 556).
The most common bacterial cause of conjunctivitis is:
Staphylococcus aureus (p. 557).
In the newborn, the most common causes of conjunctivitis are:
A) Staphylococcus aureus
B) Haemophilus influenzae
C) Chlamydia trachomatis
D) Streptococcus pneumonia
C) Chlamydia trachomatis. Also, Neisseria gonorrhoeae is a common cause.
Viral conjunctivitis is usually characterized by:
A) Inflammation, purulent discharge, and mild pain
B) Purulent discharge with occasional eyelid edema
C) Mucoid discharge and lymphadenopathy
D) Stringy discharge and itching
C) Mucoid discharge and lymphadenopathy (p. 561)
True/False. The use of eye drops such as Visine may help with the redness of conjunctivitis.
False. Avoid the use of vasoconstricting eye drops such as Visine to rid the eyes of redness. Rebound vasodilation may occur, and with it the redness returns. This leads to repeated frequent use of the drops to keep the eyes from being red but does not treat the actual cause of the redness (p. 562).
True/False. Therapeutic management of nasolacrimal duct obstruction involves a “wait-and-see” approach.
True. (p. 563)
True/False. The majority of cases of nasolacrimal duct stenosis resolve spontaneously by 12 months of age.
True. (p. 563)
___ is a localized infection of the sebaceous gland of the eyelid follicle, usually caused by a bacterial invasion.
Hordeolum (p. 563)
___ is a chronic painless infection of the meibomian gland.
Chalazion. (p. 563)
___ refers to chronic scaling and discharge along the eyelid margin.
Blepharitis. (p. 563)
Of the following eyelid disorders, which is likely the most painful?
A) Hordeolum
B) Chalazion
C) Stye
D) Blepharitis
A) Hordeolum is usually painful. (p. 563)
True/False. A hordeolum will usually resolve spontaneously.
False. Hordeolum and blepharitis both require antibiotic treatment. A CHALAZION will usually resolve spontaneously. If it does not, it may require minor surgical drainage (p. 564).
A 3-year old arrives in the clinic presenting with marked eyelid edema and purplish color of the eyelid, but with unaffected visual acuity and no discharge. What do you suspect?
A) Hordeolum
B) Chalazion
C) Periorbital cellulitis
D) Blepharitis
C) Periorbital cellulitis (p. 564)
True/False. Patching of the eye with a corneal abrasion is no longer recommended.
True. Patching of the eye with a corneal abrasion is no longer recommended, as children are often able to open the eye under the patch, which causes drying of the eye and further irritation, possibly contributing to prolonged recovery from the abrasion (p. 567).
Another name for farsightedness is what? What about nearsightedness?
Hyperopia; myopia. (p. 568)
Laser surgery for vision correction is not recommended by the American Academy of Opthamology until how old?
21 years old (p. 568), because of the continuing refractive development in the child’s vision through adolescence.
___ refers to the misalignment of the eyes.
Strabismus (p. 570)
Review question! Most children have strabismus intermittently, but this usually resolves by how old?
3-6 months of age. Intermittent strabismus that persists past 6 months of age or constant strabismus at any age warrants referral to an ophthalmologist for further evaluation (p. 570).
___ refers to poor visual development in the otherwise structurally normal eye.
Amblyopia (p. 570).
Which of the following is an accurate treatment for amblyopia (select all that apply)?
A) Patching for several hours per day
B) Putting atropine drops in the weaker eye
C) Vision therapy
D) Eye muscle surgery
A, C, D. Treatment involves using atropine drops in the BETTER eye (once daily). (p.570)
True/False. As with adult glaucoma, therapeutic management of infantile glaucoma is focused on medical management.
False. Unlike adult glaucoma, in which medical management is the first step, therapeutic management of infantile glaucoma is focused on surgical intervention (p. 571).
True/False. In a child with a congenital cataract, the red reflex will not be observed in the affected eye.
True (p. 571).
True/False. Breastfed infants have a higher incidence of acute otitis media than formula-fed infants.
False. The reverse in true, and breast milk’s immunologic benefits are well known (p. 577).
___ refers to the presence of fluid within the middle ear space, without signs or symptoms of infection.
___ refers to the presence of fluid within the middle ear space, without signs or symptoms of infection.
Evaluation of hearing is recommended when OME lasts ___ or more if language delay, hearing loss, or a learning problem is suspected.
3 months or more (p. 578).
This type of hearing loss results when transmission of sound through the middle ear is disrupted, as in the case of OME.
Conductive hearing loss (p. 580)
This type of hearing loss is caused by damage to the hair cells in the cochlea or along the auditory pathway.
Sensorineural hearing loss (p. 580)
Common signs and symptoms reported that may indicate hearing loss include: When the infant does not turn to sound by ___ months of age; when he does not babble by ___ months of age; when he does not speak by ___ years of age.
4; 6; 2 years (p. 581)
Myelinatization is usually complete by how old?
2 years of age (p. 795)
True/False. Deep tendon reflexes are present at birth.
True. (p. 795)
True/False. Sebaceous glands are present at birth.
True. (p. 877)
True/False. Cellulitis is usually preceded by skin trauma.
True. (p. 884)
Which of the following is accurate with regard to home burn care?
A) Applying ice to superficial burns promotes vasoconstriction and decreases edema and the possibility of blistering
B) The application of butter or cream promotes lipid formation and skin hydration, reducing healing time
C) Acetaminophen or ibuprofen are the most useful in the treatment of pain or inflammation
D) Breaking blisters and covering with a loose adhesive bandage like Band-Aid is the most effective treatment for second-degree (partial-thickness) burns.
C. (p. 905)
Which of the following is NOT true about a child's skin?
A) Skin thickness and characteristics reach adult levels around age 12-13.
B) The infant's epidermis is thinner and loses heat more easily
C) Increased water content of the skin puts the infant at increased risk of blister development
D) Children with dark skin tend to have more pronounced cutaneous reactions than children with lighter skin
A. The child's skin thickness and characteristics reach adults levels in LATE teenage years. (p. 907)
Without looking at the back of this card, what is the difference between a genotype and phenotype?
Genotype is the specific genetic makeup of an individual. It is internally coded inheritable information and refers to the particular allele.

The phenotype is the outward characteristic of the individual.
Offspring of an affected parent with an autosome dominant gene will have a ___% chance of inheriting two normal genes (disorder-free).
50% chance (p. 1064)
Name four common types of genetic disorders that follow the autosomal dominant pattern of inheritance.
Nancy Has A Point

Neurofibromatosis
Huntington's Disease
Achondroplasia
Polycystic kidney disease

(p. 1064)
Both Bob and Phyllis are carriers of Tay-Sachs disease, an autosomal recessive inheritance. What is the percent chance that their offspring will inherit 2 normal genes? What is the chance they will inherit one normal gene and one abnormal gene (carrier)? What is the chance they will inherit the disorder?
25%; 50%; 25% (p. 1065)
Why is a man more likely to exhibit an X-linked inheritance disorder?
A male has only one X chromosome and, therefore, all the genes on his X chromosome will be expressed (the Y chromosome carries no normal allele to compensate for the altered gene). (p. 1065)
True/False. There is no male-to-male transmission of X-linked recessive inheritance.
True, since no X chromosome from the male is transmitted to male offspring. (p. 1065)
Hemophilia, color blindness, and Duchenne muscular dystrophy are all examples of:
A) Autosomal dominant disorders
B) Autosomal recessive disorders
C) X-linked dominant disorders
D) X-linked recessive disorders
D) X-linked recessive disorders (p. 1065)
True/False. X-linked dominant disorders are more severe in males.
True. In females, even though the gene is dominant, having a second normal X gene offsets the effects of the dominant gene to some extent, resulting in decreasing severity of the disorder. (p. 1066)
Hypophosphatemic (vitamin D-resistant) rickets and fragile X syndrome are examples of:
A) Autosomal dominant disorders
B) Autosomal recessive disorders
C) X-linked dominant disorders
D) X-linked recessive disorders
C) X-linked dominant disorders (p. 1066)

These disorders are rare.
True/False. Spina bifida is considered an autosomal dominant disorder.
False. Many of the common congenital malformations, such as cleft lip, cleft palate, spina bifida, pyloric stenosis, clubfoot, congenital hip dysplasia, and cardiac defects are attributed to multifactorial inheritance. (p. 1066)
True/False. Mitochondria are inherited almost exclusively from the father.
False. Mitochondria are inherited almost exclusively from the mother. (p. 1066)
This is a nontraditional inheritance pattern by which the expression of a gene is determined by its parental origin. In this pattern, both the maternal and paternal alleles are present, but only one is expressed; the other is inactive.
Genomic imprinting (p. 1067)

Note: Genomic imprinting does not alter the genetic sequence itself, but affects the phenotype observed.
True/False. All fetuses that contain monosomies abort in early pregnancy.
True. (p. 1067)
Which of the following pairs is incorrect?
A) Triple/Quad screening --> Down syndrome, Trisomy 18
B) Amniocentesis --> chromosomal/genetic abnormalities
C) Chorionic villi sampling (CVS) --> Neural tube defects
D) Ultrasound --> structural malformations
C. CVS cannot detect alpha-fetoprotein levels; therefore, does NOT detect neural tube defects (p. 1073)
You are caring for a newborn who received no antepartum treatment or screening. Upon assessment, you note the infant is particularly "floppy." Knowing what you know about congenital and chromosomal abnormalities, what condition should you begin checking for other indications of?
Down syndrome (p. 1084)
An infant arrives in the clinic for immunizations, and you note a prominent occiput, low-set ears, severe hypotonia, and hypoplasia of fingernails. Without looking at his chart, what do you suspect he has?
A) Down syndrome (Trisomy 21)
B) Edwards syndrome (Trisomy 18)
C) Patau syndrome (Trisomy 13)
D) Turney syndrome
B) Edwards syndrome (Trisomy 18) (p. 1087)
True/False. Turner syndrome affects females only.
True. Turner syndrome is a common abnormality of the sex chromosome, and the phenotype is female. (p. 1087)
Webbed neck is a characteristic sign of ___.
Turner syndrome (p. 1088)
____ is the most common sex chromosomal abnormality.
Klinefelter syndrome.
Turner and Klinefelter syndrome are considered:
A) Monosomies
B) Sex chromosomal abnormalities
C) Autosomal dominant
D) Autosomal recessive
B) Both are sex chromosomal abnormalities (p. 1088-1089)
This is the most common inherited cause of intellectual disability.
Fragile X syndrome (p. 1089)
These are the hallmark of neurofibromatosis.
Cafe au lait spots. (p. 1092)

Note: If more than SIX cafe-au-lait spots are present, neurofibromatosis should be suspected.
This is a neurologic disorder in which the child cannot organize sensory input used in daily living.
Sensory processing disorder (p. 1112)
If a child cannot speak in sentences by ___ months of age, does not have understandable speech 50% of the time by ___ years, cannot sit still for a short story by ___ years, or cannot tie shoes, cut, button, or hop by ___ years, refer the child to be evaluated with a learning disability.
30 months; 3 years; 3-5 years; 5-6 years (p. 1112)
Intellectual disability is generally organized according to severity.

Mild: IQ ___ to ___.
Moderate: ___ to ____
Severe: ____ to ____.
Profound: ____ to ____.
Mild: IQ 50-70
Moderate: IQ 35-50
Severe: IQ 20-35
Profound: IQ less than 20

(p. 1113)
The (ICF/ECF) contains 2/3 of our body water.
ICF (slide 3, Fluid and Electrolytes ppt.)
The sodium-potassium pump is considered (vesicular transport/active transport).
Active transport
A child on mechanical ventilation is going to have (greater/fewer) fluid requirements.
Fewer. (slide 13, Fluid and Electrolytes ppt.)
Explain the formula for administering IV fluids to an infant or child.
100 mL/kg body weight for the first 10 kg; 50 mL/kg of body weight for the next 10 kg; 20 mL/kg of body weight for the remainder of body weight in kg.

This is the MINIMUM baseline requirement for children.
A child weighs 7.4 kg. How much IV fluid should you administer over 24 hrs?
30.8 or 31 mL/hr (p. 390)
A child weighs 16 kg. How much IV fluid should you administer over 24 hrs?
54 mL/hr (p. 390)
A child weighs 30 kg. How much IV fluid should you administer over 24 hrs?
71 mL/hr (p. 390)
Review question! D5W acts as an (isotonic/hypertonic/hypotonic) solution inside the body.
HYPOTONIC!
With regard to fluid and electrolyte balance, mottled appearance and head-bobbing are ominous signs of WHAT?
Shock! (slide 25, Fluid and Electrolyte PPT)
Over-excitability, nervousness, tingling sensation, tetany, and seizures are all signs/symptoms of what?
These are all indicators of CNS involvement in ALKALOSIS. (slide 29, Fluid and Electrolyte PPT)
Lethargy, diminished mental capacity, delirium, stupor, and coma are all signs/symptoms of what?
These are all indicators of CNS involvement in ACIDOSIS. (slide 28, Fluid and Electrolyte PPT)
True/False. A child will often exhibit normal BP when going through shock.
True. Hypotension is a LATE sign of shock. (slide 33, Fluid and Electrolytes PPT)
True/False. The rule of nines is not recommended for small children.
True. The rule of nines is not recommended in small children because there is a high margin of error. (slide 46, F&E ppt, panopto).
The child's hand accounts for ___% of the body surface area.
1%
True/False. Fluid resuscitation begins at the time the child arrives in the ER.
FALSE! Resuscitation begins at the time of injury, not at the time the pt arrives in the ER! Fluid adjustments may need to “catch up” the time between injury & the time when actual resuscitation begins.
(slide 53, F&E ppt)
Which of the following is NOT indicated in the first 24 hours of severe burn?
A) Crystalloid solution like LR
B) Colloid suspension
C) Infection control
D) Pain relief
B) Colloids are NOT advised in the first 24 hours, because there is a capillary leak going on. If colloids are administered, they are just going to weep it out into their wound, and the wound will swell more.

Note: Never give pain medication before you have started fluid resuscitation!
How much LR are children given in the first 24 hrs? (What is the formula?)
4 ml X KG X %TBSA burned + maintenance fluid

Note: Give 1/2 this number in the first 8 hours.

(slide 54, F&E ppt)
True/False. It is important to premedicate burn injury patients before fluid resuscitation has begun.
FALSE!
What is the gold standard for monitoring volume status in burn patients?
Urine output! (1cc/kg/hr)
Remind me. What is the difference between MCV and MCHC?
MCV: Average size of the RBC (Normocytic, microcytic, macrocytic)
MCHC: A calculated value that reflects the concentration of Hgb inside the RBC (Normochromic, hypochromic)
For what reason would you give a child packed red blood cells? Whole blood? Plasma?
PRBCs: Severe anemia, thalassemia, sickle cell disease
Whole blood: Acute hemorrhage or trauma
Fresh-frozen plasma: Hemophilia
What is the treatment for iron toxicity? (This is a review question!)
Deferoxamine! (YAY, PHARM!)
Remember “pink kool-aid syndrome”? When the Hgb is diluted in the cell, which of the following words would you associate with it?
A) Polycythemia
B) Microcytic
C) Hypochromic
D) Normochromic
C) Hypochromic
Note: This is associated with MCHC!
Which of the following is NOT associated with iron deficiency anemia?
A) Lack of iron supplementation after age 6 months in breastfed infants
B) Overuse of antacids
C) Excessive weight loss
D) Cow’s milk consumption before 12 months of age
E) Low socioeconomic status
C) Excessive weight loss. Excessive weight GAIN is a risk factor for iron-deficiency anemia. (p. 923)
“Spooning” of the nails is associated with what condition?
Iron-deficiency anemia.
Which of the following indicates a need for further instruction in the mother of a child with pernicious anemia?
A) As long as action is taken to address the anemia, you won’t call children’s services.
B) Pernicious anemia is caused by a lack of intrinsic factor.
C) My child will need monthly injections of Vitamin B12 until puberty.
D) If left untreated, this condition can lead to exhaustion and memory loss.
C) My child will need monthly injections of Vitamin B12 until puberty.
Inform the parent that injections will be required throughout the child’s life. (p. 925)
Lead poisoning can lead to:
A) Hypochromic, microcytic anemia
B) Hyperchromic, macrocytic anemia
C) Normochromic, microcytic anemia
D) Normochromic, macrocytic anemia
A) Hypochromic, microcytic anemia (p. 925)
PATHO REVIEW QUESTION! What is TICS?
TICS is a good way to remember microcytic anemia. Remember:
Thalassemia Syndrome
Iron deficiency anemia
Anemia of Chronic Inflammation
Sideroblastic anemia
PATHO REVIEW QUESTION! What is a good way to remember macrocytic anemias?
BIG FAT RED CELLS!
B-Vitamin B12 or Cobalamin Deficiency
I - Inherited - Rare disorders such as orotic aciduria, Lesch- Nyhan syndrome
G-Gastroentestinal disease or surgery
F-Folic Acid Deficiency
A-Alcoholism
T-Thiamine responsive
R - Reticulocytes- Reticulocytes are larger than the mature red cell and may inflate the MCV
E- Endocrine - Hypothyroidism
D-Dietary - Lack of dietary folate, B12, protein, or lipids may contribute to the megaloblastic anemia.
C - Chemotherapeutic Drugs
E-Erythroleukemia
L- Liver Disease
L- Lesch-Nyhan Syndrome
S-Splenectomy
This type of anemia is characterized by the failure of the bone marrow to produce cells.
Aplastic anemia
True/False. Infants with sickle cell anemia are usually asymptomatic until 3-4 months of age.
True. They are asymptomatic until 3-4 months of age because Hgb F protects against sickling. (p. 927)
Why might sickle cell children have an increased incidence of enuresis?
Kidneys cannot concentrate urine effectively. (p. 928)
Which of the following might you note in a child with sickle cell anemia (select all that apply)?
A) Erythema and petechiae on the conjunctiva and gums
B) Scleral icterus
C) Jaundice of the skin
D) Pallor of the skin, palms, and soles
E) Hypothermia and bradycardia
B, C, D. (p. 929-930)
You have just arrived at the clinic for the day shift and are assessing your patients. Which of the following patients is considered emergent (which should you focus on first)?
A) 11 month old with swelling of the hands and feet and history of sickle cell disease
B) 14 year old, arriving for her Vitamin B12 injection, complaining of weakness and lightheadedness.
C) A 2-year-old in for possible lead poisoning whose serum values came back at 18 mcg/dL.
D) A 13-year-old hemophilic patient who is 20 minutes late on his infusion of Factor IX.
A. (See p. 930). Immediately report symmetric swelling of the hands and feet in the infant or toddler. Termed dactylitis, aseptic infarction occurs in the metacarpals and metatarsals. Occurrence before age 1 year is predictive of severity of illness.
Arrange the following cases in order of most emergent to least emergent:
A) A 2-year old with partial-thickness burn to his foot and ankle whose blister popped overnight.
B) A 6-year-old African American girl complaining of thirst and extreme pain in her joints
C) A 13-year-old hemophiliac boy with significant swelling and discoloration of the knee
D) A screaming 3-year-old diagnosed with Fragile X syndrome
B, C, A, D. (A and C are negotiable.)
Which of the following pain medications should you avoid in a child undergoing a sickle cell crisis?
A) Advil (Ibuprofen)
B) Meperidine (Demerol)
C) Norco (Acetaminophen plus Codeine)
D) Hydromorphone (Dilaudid)
B) Avoid repeated use of Meperidine (Demerol) for pain management during sickle cell crises because it has been associated with an increased risk of seizures when used in children with sickle cell anemia (p. 932).
A 1-year-old child arrives in the clinic accompanied by her mother. She has a history of FTT, and the mother states she has always been “paler than other babies.” Upon assessment, you note a prominent forehead and yellowing of the sclerae. What do you suspect?
A) Iron-deficiency anemia
B) Pernicious anemia
C) Sickle cell disease
D) Thalassemia
D) Thalassemia is characterized by pallor, jaundice, failure to thrive, hepatosplenomegaly, and jaundice. Iron overload related to thalassemia leads to bony changes such as frontal bossing and maxillary prominence. (p. 934)
What is the only FDA approved preventative treatment for contact dermatitis related to poison ivy, oak, or sumac.
Ivy Block (p. 892)
Hemophilia Type A is a (factor VIII/factor IX) deficiency.
Factor VIII (p. 936)
Henoch-Schonlein Purpura is a condition that, in children, develops in association with what?
A viral or bacterial infection (p. 937). In adults, the condition is usually caused by drugs or toxins.
Which disorder is caused by the deficiency of the “glue” that adheres platelets to sites of injury?
Von Willebrand disease. Von Willebrand factor serves two functions: to bind with factor VIII, protecting it from breakdown, and to serve as the “glue” that attaches platelets to the site of injury. Deficiency in this factor results in a mild bleeding disorder (p. 941).
What is the purpose of Desmopressin in the treatment of vWD or hemophilia?
Demospressin may be used to release the factors necessary for clotting. Desmopressin raises the plasma level from stores in the endothelium of blood vessels; this releases factor VIII and vWF from these stores into the bloodstream (p. 941).
True/False. The majority of hearing impaired children have two normal hearing parents.
True (slide 8, Hearing Presentation ppt.)
When is the critical period for hearing development?
Birth-3.5 years (this is the time of maximal plasticity). (Slide 18, Hearing ppt.)
The ear is fully formed at ___ weeks.
24 weeks (slide 19, Hearing ppt).
A 6-month old child will most likely exhibit which of the following developmental milestones?
A) Looks at family members and common objects when named
B) Repeats a sound when the adult echoes the child
C) Follows simple commands
D) Says “uh-oh” or “ow,” or “mama/dada”
B) Repeats a sound when the adult echoes the child (slide 21, Hearing ppt)
What is the gold standard for measuring auditory sensitivity?
Audiogram (slide 32, Hearing ppt)
In (conductive/sensorineural) hearing loss, hair cells in the cochlea are damaged or diminished in number.
Sensorineural. Note: 90% of hearing loss is sensorineural! (slide 40, Hearing ppt).
Medical guidelines indicate that all infants should be screened no later than how old?
No later than ONE MONTH OLD. (slide 49, Hearing ppt.)
Hearing loss should be diagnosed by how old?
3 months old (slide 49, Hearing ppt).
Amplification (hearing aids) should be fit by how old?
By 6 months old, or within 1 month of diagnosis. (slide 49, Hearing ppt)
This type of testing involves a head-turn response reinforced with light-up, mechanical toy or short cartoon on a TV.
Visual Reinforcement Audiometry (usually done 8 months-2.5 years). (slide 57, Hearing ppt)
Bone-anchored hearing systems are usually used at age ___, when the thickness of the skull is appropriate.
5-7 years old. (slide 71, Hearing ppt)
Note: Bone anchored hearing systems can also be used in single-sided deafness, as the vibration will transmit over to the other ear.
Cochlear implants are usually reserved for children age ___ and older.
12 months (slide 75, Hearing ppt)
True/False. A cochlear implant is not a cure for hearing loss.
True. (slide 82, Hearing ppt)
True/False. Persistent strabismus should be evaluated if it persists beyond 6 months of age.
False. Persistent strabismus should be evaluated at ANY TIME! (slide 2, Disorder of the Eyes or Ears ppt).
Which of the following drugs are known to cause ototoxicity (select all that apply)?
A) Vancomycin
B) Lasix
C) Aminoglycosides
D) Betamethasone
E) Digoxin
A, B, C.
These are the most common cause of visual difficulties in children.
Refractive errors (slide 16, Disorder of the Eyes or Ears ppt)
Difficulty with writing, spelling, and composition is called:
A) Dyslexia
B) Dyscalculia
C) Dysgraphia
D) Dyspraxia
C) Dysgraphia
Problems with manual dexterity and coordination is called:
A) Dyslexia
B) Dyscalculia
C) Dysgraphia
D) Dyspraxia
D) Dyspraxia
Difficulty with writing, reading, and spelling is called:
A) Dyslexia
B) Dyscalculia
C) Dysgraphia
D) Dyspraxia
A) Dyslexia
Signs that might indicate a learning disability include the inability to phrase sentences by ___ years, the inability to use speech that is understandable at least 50% of the time by ___ years, the inability to tie shoes, hop, or cut scissors by ___, and the inability to sit for a short story by ___ to ___ years.
Signs that might indicate a learning disability include the inability to phrase sentences by 2.5 years, the inability to use speech that is understandable at least 50% of the time by 3 years, the inability to tie shoes, hop, or cut scissors by kindergarten, and the inability to sit for a short story by 3 to 5 years. (slide 5, Cognitive or Mental ppt)
Warning signs of autism include not babbling by ___ months, not pointing or using gestures by ___ months, not using single words by ___ months, no two-word utterances by ___ months, or losing language or social skills at any age.
Warning signs of autism include not babbling by 12 months, not pointing or using gestures by 12 months, not using single words by 16 months, no two-word utterances by 24 months, or losing language or social skills at any age. (slide 11, Cognitive or Mental ppt)
Which of the following is not recommended in treating ADHD patients?
A) The use of “drug holidays”
B) Administering meds after meals
C) Administering only on school days or when needed
D) Monitor for seizure activity
D) Psychostimulants are not known to be associated with seizure activity.
Which of the following are clinical manifestations of childhood schizophrenia (select all that apply)?
A) Expressive aphasia
B) Rocking and arm-flapping
C) Manic and depressive states
D) Anxiety
E) Motor or vocal tics in times of stress
A, B, D.
What is the process of regurgitation and swallowing that regurge called?
Rumination. Occurs mostly in infants.
Pica is most commonly associated with what age group?
Toddlers