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84 Cards in this Set

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milestones:
social smile, lifts head to 45 and eyes follow to midline

COOS
2 mo
milestones:

laughs and aware of parents, localizes sound, lift headto 90 and eyes follow past midline
4 mo.
milestones:

can tell parents from others, stranger anxiety, rolls over,holds body up w. hands, sits alone, BABBLES
6 mo
milestones:

paddy cake = interactive games, crawls, grasps w/ thumb, first word

CRAWLING + FIRST WORD!!!
9 mo
milestones:

separation anxiety, pulls to stand, walks w help, pincer grasp, makes 2 towers blocks. 5-10 word vocab
12 mo
milestones:

15-18 mo
starts walking
milestones:

parallel play, w cup or spoon, pulls to stand, walks well, and backward, makes 4 block tower, uses cup or spoon, 10-50 word vocab, 2 word sentences.
18mo
milestones:

dresses self w help, runs, climbs stairs, makes 6 tower blocks,3 word senstences
2yr
milestones:

magical thinking, climbs descends stairs, makes 9 block towers, draws circle
3 yr
milestones:

plays with others,hops on 1 foot,4 sentences, draw closed figures
4 yr
milestones:

can tell fantasy from reality, skips, draws person, fluent speech
6 yr
milestones:

ties shoelaces
5 yr
milestones:

potty training, gender acknowledgement, and wash hands
between 2-3 yrs
pediatric visit scehdule
1 wk post birth and at 1mo.

2 mo visit then q2mo till 6 mo.

from 6-18mo q3mo.

2 yr visit and then annually.
initiate solid foods at

initiate whole cow's milk at

SEE THE dentist
6mo.

12 mo.

2-3 yo
#1 cause of death in adolescence
accidents
what vaccines are given at the 1-2 mo visit?
hepb, rota drops, dtap, hib, pcv (pneumococcal) ipv (polio)
total doses of peds vaccines:

hepb
dtap
hib
polio
pneumovaxx
vzv-
mmr-
hepa
hpv
mcv
flu
hepb=3
dtap- 5 + TDAP at 11-12yo
hib- 4
polio=4
penumo -4
vzv-2
mmr-2
hepa-2
hpv-3
mcv4 (meningococus)-2
flu-annually after 6mo.
tanner stages for male:

prepubertal, small genitals no hair
1
tanner stages for male:

testicular and scrotal enlg, skin becomes coarser
fine genital and axillary hair
2
tanner stages for male:

penile enlargement, further testicular growth, further growth of hair = growth phase!!
3
tanner stages for male:

glans enlargement, darkening of scrotal skin, coarse hair spreads over much of pubic region
4
tanner stages for male:

adult genitalia, coarse hair extends from pubic region to medial thighs
5
immune disorders show their faces after
3 mo , when maternal immunity wears off
CATCH22 deletion, see thymic and pth hypoplasia, congenital and heart disease. tetany and frequent viral and fungal infections common b/c lack T cell function,

ca, vit d replacment necessary
digeorge - cxr absence of thymic shadow

lo serum ca
persistent mucus membrane infection and of the skin, nails, etc - candida albicans is the agent, a/w t cell def. frequent a/w adrenal pathology. decreased IgG possible, c-albicans anergy test poor rxn
chronic mucocutaneous candidiasis
x-linked disorder with boys seeing bacterial infections after 6 mo, recurrent infection, b cell def - no b cells in smear, and low ig levels
X linked agammaglobulinemia
increased incidence of resp and gi tract infections, decreased iga and normal levels of allother ig's
iga def
defect in t cell cd40, encapsulated bacteria infection common, pulmonary and gi infxns, hi igM and possible decreased hgb,hct plts and neutrophils.
hyper IGM
common variable immune def
autosomal disorder of b cell diff -increased risk of malignant neoplasms and autoimmune disorders, increased resp and gi infections from2nd decade of life, low igG levels, both men and women effected, decreased CD4-Cd8 ratio,lo IG levels, poor response to vaccines
this pt cannot be given any live or attenuated vaccines (mmr, vzv, tb), absent t cells and ab function, pts experience significant recurrent infections by all types of pathogens, fatal at early age - need bone marrow transplant
scid
wiskott aldritch syndrome
x-linked - very susceptible to encapsulated bacteria, a/w eczeyma, and thrombocytopenia

prop splenectomy ab prop important

easy bleeding w/ these pts - decreased plts, decreased igM
ataxia-talengectasia
ar - causing cerebellar dysfunction, cutaneous talngectasias, increased risk of ca, impaired t cells and iga

see after 3 yrs age
defect of neutrophils - they cant digest engulfed bacteria, recurrent bacterial and fungal infections

see chronic: cutaneous, pulmonary, perirectal, abscesss, lymphadenopathy

cells lack nadph oxidase
cgd
neutrophil chemotaxis defect, igE is high, chronic dermatitis, recurrent skin abscess and pulmonary infections, patients commonly have coarse facial features and retained primary teeth, eosionophilia
hyper igE - job syndrome
ar- dysfunction of neutrophils, recurrent staph, and strep infections, gram- bacteria and fungal infections a/w abnormal plts, albinism, neurologic dysfunction.
chediak higashi
abnormal facies, uri, skin and short stature inability of neutrophil to leave circ
LAD - leuckocyte adhesion def
female short sttaure, 45xo, what other defects seen?
turners

coarctation of aorts, craniofacial issues, neck webbing, low occiptal hairline, protruding ears, increased incidence of renal and cardiac defect.
47xxy- tall thin male
kleinfelter's

testicular atrophy, mr, infertile
anytime there is an extra x or y increase risk for?
mr
comorbidities w/ downs?
WE ALL GO DOWN TOGETHER

ALL - lymphoma

ANNULAR PANCREAS

alzheimers

CELIACS

DUODENAL ATRESIA

HIRSCHSPRUNG'S

FAILURE TO PASS MECONIUM

FIRST TRIMESTER US - INCREASE IN NUCHAL TRANSLUNCENY
wolf-hischorn syndrome
a deletion syndrome - 4p16

mr, mutiple craniofacial abnormalities, seizures
skinny smiles
angelman - 15q from mom
fat daddy
prader willi -15q from dad
a/w digeorge, cleft palate and speech disorders, mild mr, overbite and cardiac complications
velocardiofacial -22q11
mcc of celulitis and sx
staph or gp a strep or mrsa

seen w. ivda and dm

h/p - erythema, swollen and painful skin, myalgias, chills, fever and lymphax, increased wbc, esr and crp

blood culture nescesary but not wound or skin

**can becomes necrotizing
subq collection of pus and commonly caused by staph bacteria, occurs as a collection of multiple infected hair follicles...usually mrsa
skin abscess
apocrine gland inflammation in groin or axilla, or perineum, can lead to scarring..erythematous, fluctuant, and required i and d and abs for tx
HIRADENTITIS SUPRATIVA
tx regiment for hiradentitis supp
tetracycline ++ macrolide (azithro) + steroids intralesional + ocp and or spirinalactone or acutane (severe)

**same as tx for acne vulgaris
s pyogenes or gp a strep = infection that crosses fascial planes, leading to extensive soft tissue destruction and you see red, skin w/ loss of sensation, crepitus underneath and purple discoloration and bullae over the infected region
necrotizing fasciitis
management for nec fasc?
surgical debridement, i and d and iv vanc usually

ct shows subq pockets of air
dry gangrene mcc
necrosis from vasc insuff features hard and dry skin
wet gangrene mcc
acute vascular obstruction, blistering, swelling and infection, rotten smelling skin, hotn, prior skin infection.
impetigo is contagious, h/p? and tx?
h/p - kids, staph and gp a strep, yellow crusted lesions, facial itchyness, wash all areas and

tx - eryhtromycin, topical abs, dont share towels

may be caused by mrsa

**if mrsa suspected - tmp-smx +rif or minocin +rif or clind + rif or linezolid + rif

mild - use topical ab

moderate - use oral ab
2 - pregnancy test are needd and lft's are montiored before starting on
acutane - isotrertnoin
contraindicated vaccines for pregnancy
vzv, flu, mmr, bcg
mode of transmission for vzv
resp droplets
when is hsv most infectious?
when active lesions are present
tx for tinea capitis and unguium
oral antifungal
intertrigo h/p and tx?
h/p = skin creases, see itchy painful and red plaques, pustules and a/w candida albicans, koh prep shows pseudohypae

topical antifungal used and nystatin and topical corticosteroid as well,
for moluscum what will labs show
shiny papules w/ central umblication

geimsa and wright stains show large inclusion bodies
diaper dermatitis vs candida caused dermatitis?
satellite lesions a/w candida
serious cutaneous allergic rxn caused by drugs, infection, or vaccination

vesicles on extremeties, palms and soles and target lesions, erythematous center surrounded by pale inner ring, erythematous outer ring

increased eosinophils,steroids help
erythema multiforme rash
drugs a/w erythema multiforme target rash

can also incite sjs
pens, sulfonamides, nsaids, ocps, anticonvulsants

hsv and mycoplasma too
toxic epidermal necrosis (TEN) labs and h/p
labs - lo lfts and wbc, lo hgb hct and tx in burn center, ivf and ivig and steroids

see significant skin sloughing and full thickness epidermal necrosis
plaques w/ yellow, greasy scales, on infant scalp, itchy and erythemtous, topical steroids and antifungals used

selsun blue also used for tx
seborrheic dermatits
CHRONIC inflammatory skin rash, you see dry skin patches w/ papules,

risk factrors - asthma, allergic rhnitis and fmhx

vesicles on dorsal surface of hands and feet, flexor surface
ATOPIC DERMATITIS AKA - eczyema
psoriasis vs eczyema
psoriasis - extensor surfaces

eczymea - flexor surfaces
psoriasis- h/p
knees, elbows see silvery plaques, bleed easily w/ scale removal (auspitz), pitted nails

seronegative for rhemtaoid
bx - thickend epidermis, nucleated cells in corneum, increased esr , arthritis usually follows
tx regiment for psoriasis
topical steroids, retinoids, tacromilus, antifungals, mtx, cyclosporine, antitnf
viral rash in kids and young adults starts as a hearld patch then erupts, itchy and oval, white scaly and on chest, back and extremeties,
rash distributes in a xmas tree like pattern
pityriasis rosea

steroids, phototherapy, erythromycin - tx
subcutaneous fat septa inflammation resulting in painful red nodules on anterior tibias,on trunk and other extrememties, a/w collagen vasc diseases, ibd -crohns

see pretibial nodules, malaise, arthralgias, fever, +aso if a/w strep
erythema nodosum
conditions a/w erythema nodosum
aso - strp infxn

pregnancy

unkwn

drugs

bhecet's disease

ibd

tb

sarcoid
+ nikoslsky sign
ten and pemphigus vulgaris
ab's to epidermis and +nik sign and painful blisters, middle age, bx - shows acantholysis, fragile blisters,bm intact

tx - steroids, azathioprine, cyclophosphamide
pemphigus vulgaris
tense bullae, hard to rupture, autoab's to epidermal bm, widespread blistering, 60age gp, and antibm ab's seen on bx
bullous pemphigoid
def of hepatic urophyrinogen decarboxylase, involved in heme metabolism
increased prophyrins in blood and need periodic phelbtomy, clq-malarial

and h/p= chronic blistering on sun exposed skin, ruptured blisters heal poorly
porphyria cutanea tarda
risk factors for porphyria cutanea tarda
etoh hepc iron od and smoking, estrogen use
precA lesions can progress to ____________ and is seen w. sun exposure yellow brown scales seen,
<5mm, tx?
sqcellca

tx -5fu

actinic keratosis, imiquimod
uvb is main risk factor for this, skin cancer, sun expposure, ak is risk factor, and see painless, red papule w. scaling or keratanizsed growths, may bleed later

mohs or surgery to alleviate this
sqqcell ca
most common skin ca, risk - sun exposure, pearly papule w/ fine vascular markings and talengectasis,least likeyl to metasitasize
bcc ca
abcde of melanoma
assymetry
border irregular
color is variable
diameter >6mm
enalargement

**depth is really important, never do a shave bx for melanaoma, >.76mm a/w increased risk of mets, and most prognotic impt factor
most likely to met skin cancer
melanoma >sq >bcc
met sites - melanoma
lung
brain
gi