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35 Cards in this Set
- Front
- Back
Clinical signs and symptoms of anaphylaxis usually occur within _ time of exposure to offending agent. |
30 minutes |
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Dz that is an IgE mediated inflammatory response in the nasal mucosa to inhaled antigen? |
Allergic Rhinitis |
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2 most common causes of perennial rhinitis |
dust mites, animal dander |
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Most effective method to diagnose allergic rhinitis? What must be stopped 4-7 days prior to testing? |
skin test with purified antigen. Must stop antihistamines! |
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Most effective class of drugs for controlling rhinitis symptoms? Other agents (4)? |
intranasal steroids most effective, than antihistamines, intranasal cromolyn Na, decongestants (beware rebound), immunotherapy |
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Chronic inflammatory skin condition characterized by dry skin, pruritus and lichenification |
Atopic Dermatitis (eczema) |
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T/F - Eczema typically begins in early infancy |
True |
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Describe the Acute and Chronic Changes of Eczema |
Acute - erythema, weeping/crusting, often 2ndry infection; |
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Diagnostic Criteria of Atopic Dermatitis |
3/4 Major Criteria |
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T/F - Exclusive breastfeeding for 6 months may decrease food allergies and eczema in an infant |
True |
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The Test for Food Allergies? |
Radioallergosorbent Test (serum IgE for food antigens) |
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Definitive Test for Food hypersensitivity |
Double blind placebo controlled food challenge |
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What is circumscribed, raised, evanexcent areas of edema that are almost always pruritic? |
Urticaria (hives) |
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2 groups at specific risk for latex allergy |
health care worksers and myelomingocele |
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Time frame btw Acute and Chronic Urticaria |
> 6 months = chronic |
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Selective IgA deficiency is characterized by serum IgA? Treatment? |
serum < 7 mg/dL, IgA cannot be replaced so management is ia treating infections and other complications |
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Most common immune deficiency |
IgA deficiency |
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How can you determine diminished antibody funciton? |
measure titers in response to childhood immunizations |
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What is Common Variable Immunodeficiency? Treatment? |
heterogenous group of disorders of hypogammaglobulinemia; |
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Increased susceptibility to infection with the first few months of life with common and opportunistic infection is common with? |
SCID |
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Management of SCID (4)? |
1. irradiated blood products |
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Describe Ataxia Telanctasia (5)? Should Avoid What? |
1. Auto Recessive Chr. 11 |
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Describe the features of Digeorge Syndrome? |
CATCH-22; |
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Describe the features of Wiskott-Aldrich Syndrome (4)? |
X linked disorder of Combined ImDef, Eczema, and Thrombocytopenia |
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What organisms are Wiskott-Aldrich patients susceptible to specifically? |
encapsulated organisms |
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Diagnostic Tests in W-A syndrome(2)? Therapy? |
CBC (thrombocytop), IgM decreased; Therapy of choice is HLA-matched BMT with IVIG and splenectomy + prophylactic abx |
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X-Linked Bruton's Agammaglobulinemia is characterized by ? Treatment? |
severe B cell deficiency with normal T cells; Treatment IVIG |
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Chronic Granulomatous Disease is predominately inherited by ? |
X-linked |
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Diagnositic Test for CGD (2). |
nitroblue tetrazolium or flow cytommetric assay |
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Treatment of CGD (5) |
1. drain abscesses |
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AutoRec condition characterized by decreased neutrophil chemotaxis, cyclic neutropenia, and pancreatic exocrine insuf. Patient often presents recurrent soft tissue infections, chronic diarrhea, and FTT. |
Schwachman-Diamond Syndrome |
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Syndrome of variable neutropenia and thrombocytopenia with gian lysosomal granules in PMNs. Also with partial oculocutaneous albinism. |
Chediak-Higashi Syndrome |
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Defiecienices of early components of complement are associated with _. |
A/I dz |
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Defiecienices of late components of complement are associated with _. |
meningococcal and gonococcal infections |
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T/F - A total serum hemolytic CH50 complement indicates fully functional pathway. |
True |