Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
absorption
|
variations in peripheral blood flow can occur and may result in unpredictable absorption of parenterally administered drugs
|
|
GI function
|
gastric pH and emptying time vary during development
|
|
distribution
|
differences in amt of body water, fat, plasma protein= different Vd
|
|
metabolism
|
phase I develops earlier than phase II in neonates
generally less effective than adults |
|
excretion
|
by 1 yo, adult renal function is attained
|
|
youngs rule
|
adult dose x (age in years/age+12)
|
|
weight
|
adult dose x (weight in lbs/150)
|
|
surface area
|
table
|
|
best method to determine how much dug to give child
|
published peds dosing
|
|
how do drugs cause kernicterus in kids?
|
compete with bilirubin for plasma proteins
BBB is not developed enough to keep bilirubin out |
|
tetracycline
|
stains teeth
|
|
growth retardation
|
amphetamine
methylphenidate |
|
aspirin
|
reyes
|