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157 Cards in this Set

  • Front
  • Back

APGAR stands for?

When is the score given?

Appearance
Pulse
Grimace (reflex)


Activity (tone)


Respiration (effort)

Given at 1 & 5 minutes

Describe what the APGAR 1 minute score evaluates

APGAR 1 minute evaluates the intra-uterine environment

Describe what the APGAR 5 minute score evaluates

APGAR 5 minute evaluates the transition between the intrauterine environment and the regular enviroment

After the 1- and 5-minute APGAR scores, subsequent APGAR scores will reflect which efforts?

Is the APGAR score predictive of outcome?

Resuscitation efforts.

APGAR is not predictive of outcome

APGAR quiz:

Blue, pale baby


HR <100
No response
Some flexion
Slow, irregular respiration

APGAR score:


0+1+0+1+1 = 3

Low APGAR scores are associated with?

Neurologic damage or necrotizing enterocolitis

"Cone head" babies/Caput succedaneum describes which presentation?

Pathological/benign? May cause what?

Babies with scalp swelling

This is benign, the swelling subsides over a few days.

May cause Jaundice

Cephalhematoma --> does it cross the suture line?

No

Subcutaneous Fat Necrosis is associated with which 4 factors?

Where do the lesions commonly present?

1. Difficult labor/delivery


2. Perinatal asphyxia (reflected in poor APGAR score)


3. Prolonged hypothermia


4. Hypocalcemia months later

Common on cheeks and buttocks

Erb-Duchenne Palsy is palsy of which plexus?


Anatomically, where is the lesion?

Brachial Plexus

C3-C4


In case of C5 --> Ipsilateral Hemidiaphragmatic Paralysis causing respiratory distress in the baby

Waiter's tip of the hand is associated with which kind of palsy?

Brachial Plexus Palsy, Erb-Duchenne Palsy

Horner is a guy, who's forehead is dry
Who has a small eye, and can't see the sky

This poem refers to which medical terms?

Anhydrosis, Miosis and Ptosis

The entire half of the baby's face is paralyzed. This would indicate a peripheral or central palsy?

Peripheral

In the case of central, it would only affect the upper or lower part of the face

Which bone is most commonly fractured during delivery?

Clavicle

Subconjunctival Hemorrhage. When does it occur, and what is the prognosis?

Occurs due to pressure during delivery through vaginal canal. Goes away over time

Cutis Marmorata in neonates is common when the child is exposed to?

In which condition would Cutis Marmorata not dissipate?

Cold temperatures

Down Syndrome

"Port Wine Stains" are assocated with which medical condition and which cranial nerve?

Uni- or Bilateral?

Sturge-Weber syndrome, CN V Trigeminal

Unliateral

A Proliferating Hemangioma in a child may present on any part of the body, and will eventually go away on its own.

What respiratory issue may it present with in a child? What type of Hemangioma would give this presentation
Finally, which position will exacerbate the symptomes?

Stridor of increasing severity, due to a subglottic hemangioma. Symptomes will be exacerbated in prone position.

Encephalotrigeminal Angiomatosis has another name. Which?

It's characterized by wikipedia as which kind of disorder?

Sturge-Weber Syndrome

Congenital Neurological and Skin disorder

Mongolian Spots are most commonly is which area of the body?

DDx for this disorder is what?

Lumbo-Sacral Area

DDx is child abuse

Erythema toxicum is a common, migratory rash in neonates. When does it appear?

Scraping the lesion will show which type of cell?

Does not appear right after birth!! Goes away within two weeks.

Eosinophils

Neonate with severe rash right after birth.

Scraping the lesions shows neutrophils.
The rash does not appear to be migratory, and Nikolsky's sign is seen.

Which pathological presentation is described?

Staphylococcal Scalded Skin

A baby with Staphylococcal Scalded Skin needs what sort of treatment?

Antibiotics and Fluids. Quickly

Define Aniridia

Lack of Iris

Aniridia is associated with which kind of tumor?
Why the association?

Wilms' Tumor

Due to deletions in the p13 band on chromosome 11

Leukocoria is associated with what?

Retinoblastoma

Galactosemia and TORCH infections can give which ophthalmological finding in a newborn?

Congenital Cataract

In the case of Microtia (gross malformation of the ear), which screening test would be appropriate?
Why?

CT scan.

To find out if the baby has developed a hearing canal.

Newborn Screening will include these 5 common conditions

1. Phenylketonuria


2. Galactosemia


3. Hypothyroidism


4. Cystic Fibrsis


5. Sickle Cell Anemia

Baby:
Fair haired, Fair Skinned, Blue eyes.
Musty odor. Eczema.
Mental Retardation

Phenylketonuria

Screen for it after 48 hrs after birth

3 main groups of etiologies of Symmetric IUGR?

1. Syndromes
2. Chromosomal anomlies
3. TORCH infections

LEARN --->
APGAR
TORCH
TANNER STAGING
DENVER II DEVELOPMENTAL ASSESSMENT

Know this!

Blueberry Muffin

Congenital Rubella

Two Complications of Potter Sequence?

1. Respiratory insufficiency (due to pulmonary hypoplasia)


2. Renal Failure

Define Malformation

Results from an intrinsically abnormal developmental process (e.g. polydactyly)

Define Disruption

Results from the extrinsic breakdown of, or interference with, and originally normal developmental process (e.g. amniotic band disruption sequence)

Define Deformation

Alteration of the final form of a structure by mechanical forces (e.g. Potter deformation sequence)

Define Dysplasia

Abnormal development that results in abnormal organization of cells into tissues (e.g. bone dysplasia)

Multiple Anomalies:
Define "Association"

Does one need to have all the factors of an association to fall into the category? -->

Non-random occurrence of multiple independent anomalies that appear together more than would be predicted by chance but are not believed to have a single etiology (e.g. VACTERL)

--> No

What does VACTERL stand for?

Vertebral dysgenesis
Anal atresia (imperforate anus)


Cardiac anomalies
TracheoEsophageal fistula (esophageal atresia)
Renal anomalies
Limb anomalies (e.g. abscent radius)

Multiple Anomalies:
Define "Sequence"

Related anomalies that come from a single initial major anomaly or precipitating factor that changes the development of other surrounding or related tissues or structures (e.g. Potter Sequence)


Multiple Anomalies:
Define "Syndrome"

A pattern of anomalies that occur together and are caused by a single known or unknown cause (e.g. Down Syndrome)

Child description:
1. Growth deficiency


2. Mental retardation


3. Personality (happy, welcoming)


4. Elfin facies

Which Syndrome?

Williams Syndrome

What are the Major medical problems encountered in Williams Syndrome?

1. Hypercalcemia


2. Supravalvular aortic stenosis


3. Renal artery stenosis --> HTN

Noonan Syndrome is similar to Turner Syndrome, except it's also featured in boys.

Instead of Coarctation of the Aorta, featured in Turner Syndrome, this is more common in Noonan --->


Pulmonic Valvular Stenosis

Do children with Turner and Noonan Syndrome display Mental Retardation?

Turner --> No

Noonan --> Yes


CHARGE association stands for?

Coloboma
Heart defects


Atresia choanae


Retardation of growth/development
Genital hypoplasia
Ear defects/hearing loss

Define Prune Belly Syndrome


What are the features of this disease?

Absence of the anterior abdominal muscles

1. Genitourinary defects


2. Cryptorchidism

Rule of weight in newborns:
By 6 months, the weight of the child should have become?

Double of BW

The appetite of the baby will slow down at which point of age?

18 months

The growth rate starts to slow down after how many months after birth?

6-12 months

Important Growth Concepts:
Myelination is complete at which age?

7 years

If the baby is fed with goat's milk, he/she will require supplementation of which compound?

Folate

How to diagnose Consitutional Growth Delay in a child?

Check Bone Age

Vitamin Deficiencies:
Thiamine (B1) ---> Beriberi

Provide 3 symptomes

1. Neuritis


2. Heart Failure
3. Encephalopathy

Vitamin Deficiencies:


Niacin ---> Pellagra (Ds Disease)

Provide 4 symptomes/complications (D)

1. Diarrhea


2. Dermatitis (worse with sun)


3. Dementia


4. Death

Vitamin Deficiencies:
Vitamin C ---> Scurvy

Provide 3 symptomes/complications

1. Pseudoparalysis


2. Scorbutic rosary
3. Mucous membrane hemorrhage

Vitamin Deficiencies:
Vitamin D causes two diseases.

Which?

1. Rickets
2. Tetany

What is the most frequent cause of stridor in infants and young children?

Laryngomalaca

The most commonly ingested foreign body is?

A Coin

Wiskott-Aldrich syndrome can be excluded by doing which test?

CBC looking for platelet count.
Normal platelets = No Wiskott-Aldrich

Howell-Jolly bodies indicates which condition?

Asplenia

Suspicion of Chronic Bacterial or Fungal infections can be excluded by doing which blood test?

ESR

Normal ESR = No infection (bacterial or fungal)

Best test to check for a complement deficiency?

CH 50

Bruton Agammaglobulinemia, a B-cell defect, is a congenital disease affecting which chromosome?

Specific finding on PE?

It's X-linked. Therefore, it's present only in boys.



PE --> Lymphoid Hypoplasia



Definitive test for diagnosing Bruton Agammaglobulinemia?

Flow Cytometry ---> Absence of circulating B-cells

Define DiGeorge Syndrome

"Microdeletions of chromosome region 22q11" - Toronto Notes

"Dysmorphogenesis of 3rd and 4th pharyngeal pouches" - Kaplan

What is the most common initial manifestation of DiGeorge Syndrome?

Hypocalcemic Seizures

What is the 2nd most common congenital chromosomal abnormality (next to Down Syndrome) ?

DiGeorge Syndrome

Patients with DiGeorge Syndrome often present with opportunistic infections. Which type of microorganism causes the infections?

Viruses

Define SCID (Severe Combined Immunodeficiency)

"Absence of all adaptive immune function +/- natrual killer function" - Toronto Notes


What is the most common primary renal neoplasm of childhood?

Wilms' Tumor (Nephroblastoma)

Name 4 DDxs of Wilms' Tumor (Nephroblastoma)

1. Hydronephrosis


2. PCKD
3. Renal Cell Carcinoma
4. Neuroblastoma

Which tumor, common in childhood, may present with HTN, gross hematuria, abdominal pain and vomiting?

Wilms' Tumor (Nephroblastoma)

Wilms' Tumor (Nephroblastoma) may have ___________ metastasis at time of diagnosis. (may also have symptomes suggesting location of metastasis)

Pulmonary metastasis

Wilms' Tumor presentation of "Asymptomatic, unilateral abdominal mass" is how common in patients?

80% of patients

WAGR syndrome is an abbreviation of which four conditions?

Which chromosomal anomaly does it represent?

Wilms' tumor


Aniridia
Genital anomalies
mental Retardation

11p13 deletion

Define the basic pathology in Beckwith-Wiedemann syndrome

It's characterized by enlargement of body organs -especially the tongue.

Also
---> Hemihypertrophy


---> Hepatoblastoma


---> Omphalocele/Umbilical Hernia

Which congenital disease carries increased risk of developing hepatoblastoma, adrenocortical tumors, neuroblastomas and rhabdomyosarcomas?

Beckwith-Wiedemann syndrome

Denys-Drash syndrome is characterized by?

Gonadal dysgenesis and nephropathy leading to renal failure

Neuroblastoma

Most common malignant tumor seen in neonatal period.


Any sympathetic plexuses may develop it.


Progression resistant to therapy.


Neuroblastoma staging system??

Find out!

Renal tumors

Polyhydramnios + abdominal mass regular finding during preg.



After birth: hematuria, hypercalcemia, hypertension


Wilms tumor vs congenital mesoblastoma nephroma

CMN is benign, Wilms malignant

Large kidney DDx

Renal cystic disease (most common), hydronephrosis, neuroblastoma, then finally tumor.

Hepatic hemangioma

Benign, orregular size,

Mesenchymal hamartoma

Most common in neonatal age, benign condition

CNS tumor with best prognosis?

Cherry tumor

Typical maligancy in children

CNS TUMORS are most common solid tumors in children.

Heart tumors

Rhabdomyoma is a hamartoma, high association with TS

Hemangioma

Most common tumor of infancy.


10% of population has hemangioma.



Tumors vs vascular malformation


Infantile hemangioma

Most common type of tymor in children, period. (10%) JD

Medication used in hemangioma?

Propanolol

Trauma, infected wounds
Lid Abscess


Respiratory infection
Bacteremia
Sinusitis

All etiologies of which disease?

Periorbital Cellulitits

Most common organisms causing Periorbital Cellulitits?

1. S. pneumoniae


2. H. influenza type b


3. S. aureus

PE -->
The eye is clearly infected, but the eyeball movements are intact. Normal vision, no proptosis

Which infection of the eye will this point to?

Periorbital Cellulitis

Definite Dx for Periorbital Cellulitis?

Tx of Periorbital Cellulitis?

No definite, diagnosis is clinical (blood culture unlikely to be positive)

Oral or IV Antibiotics


---> Cover for S. aureus and resistant gram-posititve

PE -->
Proptosis
Ophthalmoplegia --> Eyeball does not move


Chemosis, swelling, decreased visual acuity, toxic-appearing, fever, pain

Likely diagnosis?

Orbital Cellulitis

Etiology of Orbital Cellulitis?

1. From contiguous wound


2. Bacteremia


3. Paranasal sinusitis

Other names for pre-septal cellulitits and septal cellulitis concerning eye infections?

Pre-septal cellulitits --> Periorbital Cellulitits

Septal cellulitits --> Orbital Cellulitits

Organisms responsible for Orbital Cellulitits?

1. S. aureus


2. Nontypable H. influenza

Best test for suspicion of Orbital Cellulitits?

CT scan

Tx for Orbital Cellulitis?

Drainage of the infected area (it's trapping the eye making it impossible to move)

Broad-spectrum antibiotics (cover S. aureus)

Define Chemosis

The cunjunctiva becomes swollen and gelatinous in appearance.
----> Nonspecific sign of eye irritation

"Swimmers Ear" is another name for which disease?

Otitis Externa

Which organisms can cause Otitis Externa?

Which other two causes can cause the disease?

1. Pseudomonas aeruginosa (most common)

2. S. aureus (2nd most common)




Repeated wetting (Swimmer's Ear) and Repeated Trauma




Symptomes and signs on PE in Otitis Externa?

Symptomes: Significant pain, especially on manipulation of the outer ear. Conductive hearling loss

Exam: Inflamed, swollen, macerated ear canal

Eardrum itself will be normal

Define Macerated Skin

Softening and breaking down of skin resulting from prolonged exposure to moisture

Tx of Otitis Externa?

Topical antibiotic drops + Costicosteroid drops

Organisms causing Otitis Media?

1. S. pneumoniae


2. Nontypable H. influenza


3. M. catarrhalis

Risk factors for Otitis Media?

1. Infants/children (due to f. eks. shorter ear canal)


2. Formula-feeding versus breast-feeding


3. Craniofacial anomalies, Eusatchian tube dysfunction


4. Males, daycare, in contact with more germs
5. Secondhand smoke

Symptomes of Otitis Media?

1. Ear Pain (otalgia)


2. Fever


3. Purulent otorrhea (rupture)


4. Irritability


5. Diarrhea


6. ----> or could have no symptomes at all

Dx of Otitis Media?

1. Always pneumatic otoscopy


2. Full, bulging, red Tympanic Membrane


3. Sometimes retracted


4. Loss of landmarks


5. Bubbles

Why does Otitis Media with Effusion occur?



What are the symptomes?

Due to repeated infections of Otitis Media with insufficient time for effusion to resolve






Sympt --> Fullness slight or absent or TM retracted.
Very little or no erythema

Tx of Otitis Media?

Antibiotics, first line drug is Amoxicillin

Define Myringotomy, and when would you perform one?

"Tiny incision is created in the eardrum to relieve pressure caused by excessive buildup of fluid, or to drain pus from the middle ear" - Wikipedia

1. Unsatisfactory response to appropriate second-line drug


2. Any complications


3. Immune compromise


4. Neonates or very young infants with systemic signs

Any child with delayed speach should be tested for what?

Hearing problems

Quite obvious.

Complications of Otitis Media?

Hearing loss --> Most common


Also:
Acute mastoiditits


Perforation


Cholesteatoma


Meningitis (most common intracranial complication)


Labyrinthitis

Define Cholesteatoma

"Cholesteatoma is a destructive and expanding growth consisting of keratinizing squamous epithelium in the middle ear and/or mastoid process." - Wikipedia

Define Choanal Atresia

"Membranous or bony septum between nose and pharynx" - Kaplan

"Congenital disorder where the back of the nasal passage (choana) is blocked, usually by abnormal bony or soft tissue (membranous) due to failed recanalization of the nasal fossae during fetal development" - Wikipedia

Choanal Atresia is associated with which congenital syndrome?
50% non-random association

CHARGE Syndrome

Dx of Choanal Atresia?

1. Cannot pass catheter 3-4 cm


2. Fiberoptic rhinoscopy


3. Delineate exact anatomy --> CT scan

Tx of Choanal Atresia?

Oral airway or intubation, nasogastric feeds


1. Transnasal repair with stent(s)

Nasal Foreign Body
Clinical signs?
Obvious Dx and Tx

Unilateral malodorous, purulent and/or bloody discharge

Dx: May be seen with speculum or otoscope




Tx: Remove

Define Epistaxis, and name the most common source of the bleeds

Nosebleed.

Most commonly from anterior septum; Kiesselbach plexus

Common etiology of Epistaxis in children?

1. Digital trauma - nose picking


2. Dry air (winter)


3. Inflammation - URI, allergy


4. Nasal steroid sprays


5. Others - foreign body


6. Rarely bleeding disorder, vascular anomaly

Sinusitis is most commonly associated with which other form of pathology?

Can also be?

Upper Respiratory tracy Infection (URI)

Can also be self-limited

"When we talk about sinusitis in children, always think about ______"

Bacterial Superinfection

A child is born with which two sinuses? Which one is pneumatized?

When do you get the next two sinuses?

Ethmoid and Maxillary. Ethmoid is pneumatized.

Sphenoid --> 5 years




Frontal --> begins at 7-8 years , not complete until >12

Organisms responsible for Sinusitits?

Which organism is responsible for chronic Sinusitis?

1. Streptococcus pneumoniae


2. Nontypable Haemophilus influenza


3. Moraxella catarrhalis


4. S. aureus for chronic

Dx of Sinusitis is entirely historic/clinical.

Two main points make up the important history in Sinusitis. Which?

1. Duration. Persistent URI symptomes with no improvement for at least 10 days




2. Severity. Severe respiratory symptoms with purulent discharge and a temperature of at least 39* for at least 3 consecutive days

Tx of Sinusitis?

How long does the Tx last?

Antibiotics




For 3 weeks (longer than for Otitis Media)

Acute Pharyngitis
What are the two most important causes?

1. Viruses


2. Group A Beta-Hemolytic Streptococcus (pyogenes) (GABHS)
---> Strep throat

The peak age for Strep Throat is about?






Strep Throat is another name for?

5-10 years of age
(<5 --> think of viruses)



Acute Pharyngitis, caused by GABHS

If the child has underlying URI symptomes during an onset of Acute Pharyngitis, the etiology of the infection is probably?

Viral

Age of child 5-10 yrs.
Sudden onset, sore throat and fever.
Complain of headache, may also have vomiting and abdominal pain.
Symptomes may mimic appendicitis, due to enlarged abdominal lymph nodes.

What is the likely Dx?

Streptococcal Pharyngitis (Strep Throat)

PE -->
1. Red pharynx


2. Tonsillar enlargement with yellow, blood-tinged exudate


3. Palatal and posterior pharyngeal petechiae


4. Strawberry tounge


5. Red, swollen uvula


6. Increased and tender anterior cervical nodes

Likely Dx?

Streptococcal Pharyngitis (Strep Throat)

When suspecting Streptococcal Pharyngitis, which areas do you have to swab in order to get the Dx?

Is swabing necessary for the diagnosis?

Both tonsils and the posterior pharynx (make them gag)

Yes.

Palatal petechia and the a characteristic rash also seen in Scarlet Fever (Scarletina) may point to which kind of pathology?

Streptococcus Pharyngitis (Strep Throat)

Viral Pharyngitis
Pharyngoconjunctival fever is caused by which type of virus?

Adenovirus

Hand-Foot-and-Mouth Disease presents with an inflamed oropharynx in addition to vesicles throughout the mouth, hands, feet and buttocks. They are very painful, and may ulcerate.

This disease is caused by which pathogen?

Coxackie Virus

Coxsackie Virus can - in the context of Ear, Nose and Throat - cause which two diseases?

1. Herpangina


2. Hand-Foot-and-Mouth disease

Two tests used to diagnose for Streptococcal Pharyngitis?

1. First --> Rapid Strep Test (answer in 5 minutes)




2. Throat culture --> Gold Standard




Do both, it's worth waiting a couple of days for the Throat Culture before starting Tx

Which disease can be prevented by treating Streptococcal Pharyngitis within 9 days of onset?

Acute Rheumatic Fever

Tx of Streptococcal Pharyngitis?

Penicillin.
The organisms remain susceptible. For now.

4 main complications of Streptococcal Pharyngitis?

1. Retropharyngeal abscess


2. Peritonsillar Abscess


3. Rheumatic fever


4. Glomerulonephritis

Retropharyngeal Abscess, a complication of Streptococcal Pharyngitis can be caused by which two organisms?

What life-threatening condition can it cause?

Obviously, Streptococcus pyogenes, but also S. aureus

The condition may cause airway obstruction

Clinical symptomes of Retropharyngeal Abscess

Stepwise course of action when suspecting a Retropharyngeal abscess will be?

Difficulty swallowing, fever, sore throat.

1. Lateral neck film for detection


2. CT


3. Drain + Ab

A patient presents with drooling, sore throat, fever, a "hot potato voice", deviation of uvula (away).


Dx?
Tx?

Peritonsillar abscess, complication of Streptococcal Pharyngitis

Drain + Ab

Cervical Lymphadenitis

Name six infections that can cause this condition

1. Viral/bacterial pharyngitis


2. Cat scratch


3. TB/atypical mycobacteria


4. Mumps


5. Thyroglossal duct cysts


6. Branchial cleft cysts

Define Hygroma

"A subdural hygroma is a subdural body of cerebrospinal fluid (CSF), without blood"
- Wikipedia

Most commonly seen in elders after minor trauma, but can be seen in children after an infection.

Cystic Hygroma in children is most commonly an enlarged lymphnode, presenting due to problems with lymph drainage.

Indications for performing Tonsillectomy?

1. >7 DOCUMENTED strep infection in past year OR -->




2. 5/yr in each of 2 previous years OR -->




3. 3/yr in each of 3 previous years OR -->




4. Unilateral enlarged tonsil -- Neoplasm (very rare)

Three indications for performing Adenoidectomy?

1. Chronic nasal/sinus infection failing medical Tx




2. Recurrent/chronic OM with tympanostomy tubes with persistent otorrhea




3. Nasal obstruction with chronic mouth-breathing and loud snoring

Tonsillectomy and adenoidectomy is indicated when?

Upper airway obstruction from hypertrophy --> Sleep-disordered breathing and complications

APGAR quiz:

Pink baby
HR <100/min
Grimace
Active


Slow, irregular respiration

Score?

APGAR score:
2+1+1+2+1 = 7

Poor APGAR score is?

Fair APGAR score is?

Good is?

Poor 0-4

Fair 5-7

Good 8-10

TORCH infections include?

Toxoplasmosis
Other (Syphilis, Varicella, HIV and parvovirus B19)


Rubella
Cytomegalovirus (CMV)


Herpes