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9 Cards in this Set

  • Front
  • Back
M phase specific
Vincristine
Vinblastin
S specific
Thioguanine
Inhibits thymidylate synthetase
fluorouracil
Inhibits dihydrofolate reductase
methotraxate
degrased DNA by formation of free radicals
bleomycin
Administration of ______ counteracts the therapeutic effects of folic acid antagonists such as MTX
Folinic acid (leucovorin Calcium)
5-FU dosage forms
1% crm: FLUOROPLEX- BID x 14days

5% Crm: EFUDEX- BID x 14days

0.5% Crm: CARAC- QD up to a month
This can be used for actinic keratosis or basal cell carcinoma if used for greater than 14 days
5-FU Cream
Which bacterial substances induce cytokines, and which are they?
Cytokines induced:
1. IL-1
2. TNF

Gram positive inducer: Teichoic acid

Gram negative inducer: Lipid A of the Lipopolysaccharide (Endoxtoxin)