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15 Cards in this Set

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What is the primary functional difference between steroids and non-steroids?
Steriod - made of fat/lipid soluble, can pass bilipid layer without help, to change expression of DNA to produce results
Non-steroid - not made of fat/not lipid soluble, must bind to a specific receptor on the outside of the cell to produce results
What are the three antagonistic hormone pairs to know?
Insulin/Glucagon (lower blood sugar/raise blood sugar)
Atrial Naturetic Peptide/Aldosterone (lower NA, raise K/raise K, lower NA)
Parathyroid hormone/Calcitonin (destroy bone/make bone)
What are tropic hormones? What are the four to know?
Tropic hormones go from one endocrine gland to another, akaBasophils
TSH - Anterior Pituitary>Thyroid
ACTH - Anterior Pituitary>AC
LH - Anterior Pituitary>Gonads
FSH - Anterior Pituitary>Gonads
What are releasing hormones? What are the three to know?
Hormones that go from hypothalamus to anterior pituitary, and cause another hormone to be released
Thyroid Releasing Hormone - Make TSH
Corticoid Releasing Hormone (CRH) - Make ACTH
Gonad Releasing Hormone (GnRH) - Make LH/FSH
What is the difference between a primary and secondary disorder?
Primary disorder - Organ (worker) is broken
Secondary disorder - Management (supervisor) is broken
What is the functional purpose of blood within the body?
Transportation
What six substances are carried by the blood? What portion of the blood carries each?
Gasses - Plasma, RBC
Nutrients - Plasma
Wastes - Plasma
Hormones - Plasma
Water - Plasma
Minerals - Plasma
What are the four components of blood?
Plasma
Carrier, Generated from diet
White Blood cells (leukocytes)
Provide immunities
Red Blood cells (erithrocytes)
Have hemoglobin, which carries oxygen
Platelets
Clotting
What do Hemocytoblasts make? Where are they located?
Make blood cells (all), in bone marrow
What organs sense and respond to low oxygen in the blood? How long does the response take?
Sensed by liver and kidney
They send signals to make more RBC, called EPO, Erithropoeitin (hormone), goes to bone marrow, makes more cells, carry more oxygen, takes approximately 4-6 weeks to produce results
Describe what happens to "old" blood in the body
Old blood recycled in liver and spleen
Iron removed from RBCs, sent to bones
"other stuff" becomes biliverdin, which then converts to bilirubin, which becomes part of bile, goes to intestine and adds to fecal matter, produces brown "base coat" - dead liver means white poop
Sunlight also destroys bilirubin
What is a hematocrit? What is a "normal" range for this test?
Hematocrit - measure of RBC percentage in blood - usually 42-45%
What does it mean to be anemic? What variations of this condition are there?
Anemic - fewer RBC than is normal
Iron deficiency anemia - out of iron
Hemmorhagic anemia - bleeding
Vitamin deficient anemia - B(esp B12) and C missing to build RBC
Sickle cell anemia - cells die due to wrong shape
Hypertensive anemia - high blood pressure, RBC break down and die from overuse
What is hemostasis? Describe the chain of events that produces this.
Hemostasis - blood cloting
Injury
Vaso-constriction (Smaller vessels)
Platelet plug ("cork it")
Platelets release serotonin
Serotonin turns on clotting factors
Clotting factors turn on pro-thrombin activators
Pro-thrombin activators make thrombin
Thrombin makes fibrin ("jello")
Body makes plasmin ("clot buster"), once healed
What are the four basic blood types? Why is it important to know this?
A Blood - B Antibody
A and O transfusion ok
B Blood - A Antibody
B and O transfusion ok
AB Blood - No Antibody
AB, A, B, and O transfusion ok
O Blood - A and B Antibody
O transfusion ok
Wrong blood type means antibodies cause coagulation