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84 Cards in this Set

  • Front
  • Back
In this article, the report states that kavain, the major ingredient of kava, caused __
physical changes to the liver cells
which condition is NOT treated with Prozac
A) depression
B) Obsessive compulsive disorder
C) eating disorders
D) agoraphobia
E) restless leg syndrome
F) premenstrual dysphoric disorder
E) restless leg syndrome
Prozac belongs to the class of drugs called ___________ _________ re-uptake inhibitors (SSRIs)
Selective Seratonin re-uptake inhibitors
Prozac is approved for treating major depression in children __ years and older and for treating obsessive-compulsive disorder in children __ years and older.
A) 8 & 7
B) 9 & 11
C) 7 & 5
D) 6 & 9
A) 8 & 7
For treatment of mild depression, rather than drug therapy, 22% of doctors in England are now prescribing what?
excercise!
Are they suggesting that doctors should "prescribe" this, and insurance providers should pay for a trainer?
Exercise programmes organised by the Mental Health Foundation are supported by funds from the Department of Health, but are only available in some parts of the country
Depression is the third most common cause of illness among women and the tenth most common cause among men; in 2001, Australian GPs reported depression as the ___ th most common illness that they dealt with
4th
According to the World Health Organization (WHO) by 2020, depression will be the _________ biggest health problem world-wide, behind heart disease. Yikes!! I thought we were living in the best of times, with nearly everything we could want in convenience and comfort!
2nd
Before the CIA decided that LSD might be a useful tool in interrogations, who did they test it on?
A) each other
B) minorities
C) prison inmates
D) College students
A) each other
Who felt that psychoactive chemicals such as LSD would be the weapons of the future? Even argued that, say, spiking a city's water supply with acid and taking over would be much more humane than firebombing it?
A) William Creasy
B) Albert Hoffman
C) Dr. Van Sim
D) Edgar Hoover
A) William Creasy
The first description of a purified chemical that related to pheromone biology was bomykul, which drove male _______ moth's crazy.
Male silk moths
Preti found that male armpit sweat dabbed on the upper _____ of women stimulates production of ovulation-triggering luteinizing hormone.
Upper lips
Sixty-two percent of the scientists who had taken drugs used _________ while 44 percent reported using Provigil and only 14 percent had tried beta blockers like propranolol
A) Viagra
B) Cocaine
C) Ritalin
D) Methamphetamines
C) Ritalin
In the better than coffee article, how is the drug delivered to the patients?
A) injection
B) smoking
C) topical patch
D) nasal spray
D) Nasal spray
The treatment is "a totally new route for increasing arousal, and the new study shows it to be relatively benign," said Jerome Siegel, "It reduces sleepiness without causing ____________."
Without causes edginess
The drug Orexin A is used for what?
An aid to prevent the effects of sleepiness. It can possibly become a "sleep replacement" drug.
Does Orexin A have any notable effect on people who are already alert?
No
The drug Modafinil (Provogil, or Alertec in Canada) activates neurons that respond to ________
Orexin A
In the performance enhancing brain drugs article, the author suggests that it is only cheating, and therefore should be regulated, in what situation?
Formal testing of abilities
"Personal achievements impersonally achieved are not truly the achievements of persons," said the report Beyond Therapy by the US President's Council on ____________, chaired at the time by ethicist Leon Kass.
Bioethics
Studies on healthy volunteers have shown the cognitive effects of enhancing drugs to be ______, but sufficient enough to be considered helpful.
mild
information travels through a nerve cell in ____ and only ___ direction
ONE
an impulse wave moves at _____
250 mph
What would happen if a chemical were added to your brain that randomy opens channels?
random muscle contractions, twitching, uneasyness
what is the common name for Chrysanthemum
Pyrethrum
Chrysanthemum....
when grinded up can be used as an insectiside

randomly opens portals

good for flea collars

not toxic to humans
what is the chemical in chrysanthemum called
pyrethrin
Pyrethrins...
are organic

can be broken down by UV light
Pyrethroids
synthetic pyrethrins

is in raid
anything synthetic is ____ organic
NOT
How does DDT act as an insectiside?
artificially opens channels by opening a few and starting a wave
latin name for Pufferfish
tetrodotoxin
Pufferfish....
pries open portals of humans

waves of impulse spread chaotically

toxic to humans

causes spastic paralysis
what is the worlds fastest enzyme
acetycholinesterase
if a drug like AC is ingested in low doses
mild stimulant (excitory)
if a drug like AC is ingested in medium doses
high stimulant (hallucinatory)
if a drug like AC is ingested in high doses
poisonous (spastic paralysis)
Nicotine...
MIMICS AC

binds to receptors

in high doses can kill by spastic paralysis

once used as an insectiside
Toadstool
Amanita muscaria
Toadstool...
MIMICS AC

contains muscarine
acetycholine receptors come in 2 flavors..._____ & _____
nicotonic & muscarinic
If we inhibit acetycholinesterase....
AC stays in gap and binds to the receptor again, acts like a stimulant because it recycles the AC.

can cause spastic paralysis
plants that can inhibit ACase
ordeal bean with physostigmine

warfare nerve toxins developed after WWII (sarin, tabun)
Diazinon
INHIBITS ACase

insectiside

most common in water samples
Malathion
INHIBITS ACase

public mosquito spraying programs
Sevin
INHIBITS ACase

garden insectiside
Antidote for accidental ACase inhibitor (pesticide) poisoning
atropine:

covers acetycholine receptor

therefore, inhibits function of acetycholinesterase

thus, sedates the system

administered for any unexplained convulsions
Tubocurarine
acts like atropine by covering AC receptor

cobra venom acts the same way
Botulism toxin...
from bacteria
Clostridium botulini

can grow in canned foods

causes botulism (food poisoning)

prevents the release of AC from axon
Clostridium botulini causes...
slowed heart beat, muscle weakness, flaccid paralysis

*one of the most toxic substance known on Federal Antiterrorism List
Nicotana Tobacum
Tobacco
Tobacco...
MIMICS AC

used by native americans as a hallucinogen

used in ceremonies (rite of passage)

labor intensive
Fly agaric
amanita muscaria

contains muscarine
amanita muscaria.....
MIMICS AC

contains muscarine

insectiside: sliced into milk...flys drink milk...die from spastic paralysis

vikings tripped on mushrooms
Mandrake
Mandragora officinarum
mandrake....
contains scopolamine

man dragon

"doctrine of signatures" says mandrake has human shaped roots

fertility

"the fruit that excites love"

aphrodisiac

mentioned in bible

anethestic for surgery & child birth

scream when pulled from the ground

shakespeare and others wrote about the powers of mandrake
_________ is a neutotransmitter
acetycholine is a ______
the 3 big players of neurotransmitters:
seratonin, AC, epinephrine (adrenaline)
snakeroot
Rauwolfia serpentina
snakeroot (rauwolfia serpentin) contains...
Contains Reserpine

sedative from root used to treat snake bite

mongoose/cobra legend
reserpine
reduces the realease of epinephrine & dopamine

Treated mental illness

first widely used sedative in western medical for mental illness

replaces bondage, labotomy, electroshock, etc.

plant nearly harvested to extinction

decreases blood pressure

went from mental illness to heart medication, with sedative side effects
Seratonin makes us _____
feel good!
seratonin re-uptake inhibitors include
mescaline, prozak, zoloft, ecstasy
Peyote cactus
lophopora williamsii
Peyote cactus......
contains mescaline

alters recycling of seratonin

hallucinogen

used by indians of rio grande

spread in 1880s and 1890s

prohibited in early 1900s

native american church argue that it should be allowed for religious rituals
Magic Mushrooms
psilocybe mexicana
Magic mushrooms...
contain psilocybin

hallucinogenic

alters recycling of seratonin

used by native peoples of N. South America, Mexico in rituals

europeans tried to prohibit because "taking the flesh of the gods" was a "blasphemy"
Timothy Leary
psychotherapist studies magic mushrooms with students

uses pure psilocybin from Sandoz Lab

finds out LSD is cheaper
Chemicals found in ergots:
ergonovine, methergine, ergotamine
ergonovine
to induce labor
methergine
to constrict bloodvessels (pain, dry gangrene, withered flesh)
ergotamine
used to treat migraines
how was LSD synthesized
Dr. Albert Hoffman studies the alkaloids of ergots

one is lysergic acid

he adds a diethylamine group

creates LSD (lysergic acid diethylamine)
LSD...
popular in treatment of psychosis

most powerful hallucinogen known

not addicting

"drop out, turn on, tune in"

opened the door to the field of neurochemistry
CIA and military use for LSD
truth serum
What are ergots?
mass of fungal cells and plant cells
Endorphins
inhibitors in the pain and anxiety pathway

more endorphins=more brakes=calms anxiety=elavates mood=soothes stress

increases pain tolerance

increased by excercise

depress function of the anxiety pathway
opiates
opium, morphine, heroin

bind to endorphin receptors

pain killer effect
Substance P
a neurotransmitter in pain perception pathway

binds to receptors in dendrites

important in transmitting perception of chronic pain
Capsaicin
Capsicum annum

mimics substance p

causes sensation of pain that we interpret as heat

no tissue damage

in hot peppers

in heat wraps

topical treatment for arthritis

after its on for a while nerves produce substance p
Menthol
mentha arvensis

opens portals that usually open when temperature drops
Ayahuasca
main ingrediant banisteriopsis caapi
"vine of the soul"

like curare
Robigo
Roman God of Wheat and Rust

offerings made every year to prevent disease in wheat crops
Stinking Smut
diseased wheat

led to ginger bread cookies

smells like dead fish