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14 Cards in this Set

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  • Back

What drug is used to treat excessive Prolactin Secretion

(bromocriptine) Parlodel

Side effects of bromocriptine / Parlodel

Nausea


Psychosis


Insomnia/nightmares

How is Prolactin secretion controlled?

It is INHIBITED by PIH (prolactin inhibiting factor, which is actually DOPAMINE)

How do you treat hGH (Human Growth Hormone) deficiency?

With Recombinant Human Growth Hormone

How do you treat hGH (Human Growth Hormone excess)
Acromegaly and Gigantism

Somatostatin inhibits hGH secretion.
octreotide/Sandostatin injections

What hormones need to be replaced in someone with Addison's disease

Cortisol and Aldosterone
*glucocorticoids and mineralocorticoids*


What drugs replace cortisol

hydrocortisone/Cortef, or


prednisone/Medrol

GnRH pharmacology


Premature GnRH secretion-> precocious puberty

leuprolide/Lupron suppresses LH and FSH

GnRH pharmacology


INSUFFICIENT LH and FSH

Can't fix this with GnRH drugs.


RX testosterone/Androgel, etc for men


estrogen and progesterone for women

Excessive Thyroid hormone production

Block Iodine uptake
methimazole (Tapazole)


PTU (propylthiouracil) Mostly used in pregnancy

Why is PTU (propylthiouracil) mostly used in pregnancy

It is safe in pregnancy. methimazole (Tapazole) causes birth defects.

Side effects of propylthiouracil?

Liver damage. methimazole (Tapazole) is the first choice unless the patient is pregnant.

Side Effects of methimazole (Tapazole)

agranulocytosis- LOW blood count. Can put patient at risk for infections.

What symptom do you watch out for to signal agranulocytosis?

Sore throat. When you give methimazole (Tapazole) to a patient, she is given WRITTEN instructions to report sore throat.