Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
29 Cards in this Set
- Front
- Back
|
What is inflammation?
|
The succession of changes that occur in living, vascularized tissue after a sublethal injury
|
|
|
What is Acute inflammation?
|
Short in duration, accummulation of neutrophils
|
|
|
What is Chronic inflammation?
|
Longer duration, accummulation of macrophages and lymphocytes, proliferation of fibroblasts and blood vessels
|
|
|
What is the function of Endothelial cells?
|
Line the blood vessels, serve as a barrier to passage of fluid, molecules and cells
|
|
|
What is the function of Mast cells?
|
Reside in tissues near blood vessels, important reservoirs of chemical mediators for inflammation
|
|
|
What is the function of fibroblasts?
|
Located in tissue, produce connective tissue matrix
|
|
|
What is the function of neutrophils?
|
Important in acute inflammation, first line of defense vs infection
|
|
|
What is the function of monocytes?
|
reside in blood migrate to tissues and differentiate into macrophages, injest and destroy bacteria and debris
|
|
|
What are the functions of B and T lymphocytes?
|
Humoral and cell-mediated immunity
chronic inflammation |
|
|
What is the function of Basophils?
|
Circulate through the blood, reservoirs of chemical inflammatory mediators
|
|
|
What is the function of platelets?
|
Primary role in clotting factor also carry inflammatory mediators
|
|
|
What is Rubor?
|
Redness from vessel dilation and increased blood flow
|
|
|
What is Calor?
|
Heat due to vessel dilation and increased blood flow
|
|
|
What is Dolor?
|
Pain due to increased pressure on nerve endings from swelling and direct effect of chemical mediators
|
|
|
What is Tumor?
|
Swelling due to increased fluid in interstitual space
|
|
|
What is Hyperemia?
|
Increased blood flow dilation of arterioles and opening up of capillaries
|
|
|
What two chemical mediators are synthesized from Arachodonic acid?
|
Prostaglandins and leukotrienens
|
|
|
How does histamine increase membrane permeability?
|
Causes endothelial cells to restrict thus producing gaps in the vessel wall
|
|
|
What is edema?
|
Excess fluid in vessels
|
|
|
What is exudate?
|
Part of edema, seen in inflammation, protein-enriched, can be fibrinous or purulent (containing leukocytes, bacteria or debris)
|
|
|
What is transudate
|
protein poor, seen in instances of high blood pressure but epitheliam is not effected
|
|
|
What is Diapedesis?
|
Movement of leukocytes from blood to tissue, also known as extravasation
|
|
|
What is chemotaxis?
|
A reaction by which the direction of movement of cells is determined by substances in their environment, complement factor C5 is important for chemotaxis
|
|
|
What is ESR?
|
Erythrocyte sedimentation rate
|
|
|
What protein, made in the liver, is likely to be at an increased level in the blood during inflammation
|
C-reactive protein
|
|
|
What is TNF?
|
Tumor necrosis factor
|
|
|
What type of healing comes from minimal tissue damage?
|
Resolution
|
|
|
What type of healing comes from renewal of tissue by cells capable of mitosis?
|
Regeneration
|
|
|
What type of healing comes from wound replaced by scar?
|
Replacement
|
