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51 Cards in this Set

  • Front
  • Back

HYPOXIA

LACK OF OXYGEN;


LEADS TO ANAEROBIC RESPIRATION

Tay-Sachs Disease

lipid/carb accumulation;


brain cells turn to fat

Endogenous

inside body

exogenous

outside body

atrophy

decrease in cell size

hypertrophy

increase in size of cells (workload increases)


normal- muscles


abnormal- heart

hyperplasia

increase in number of cells;


normal- pregnancy


abnormal- cancer

metaplasia

cells being replaced by different type of cell

dysplasia

cells undergone atypical changes

apoptosis

destroys cells no longer needed (cancer)

necrosis

cell death in living organ/tissue;


progress into gangrene

gangrene

considerable mass of tissue undergoes necrosis

gene

unit of heredity

chromosome

linear arrangement of genes within cell nucleus


23 pair

homozygous

possessing pair of identical

heterozygous

different genes on pair of chromosomes

de novo

new

inherited

Mendelian

Euploidy

46 chromosomes

aneuploidy

gain or loss of chromosomes

Autosomal

13, 18, 21

autosomal trisomy

cell contains one extra copy of any chromosome;


most common

autosomal monosomy

cell contains 1 copy of any chromosome instead of 2; lethal

gynecomastia

enlarged male breasts

polyploidy

>2 sets of chromosome pairs, still in sets of 23

tetraploidy

92 chromosomes

triploidy

69 chromosomes

Cri Du Chat Syndrome

cat cry syndrome; deletion- loss of portion of chromosome

Fragile X Syndrome

gap in chromosome; only expressed in males

Marfan's syndrome

CT disorder;


autosomal dominant

Autosomal Dominant

abnormal gene is dominant and normal gene is recessive

Autosomal Recessive

abnormal gene is recessive and normal gene is dominant

pH

measure of H+ concentration

normal pH

7.35-7.45

buffer systems

chemical buffer, respiratory compensation, renal compensation

Normal PCO2 level

35-45 mmHg

Normal Bicarbonate buffer (HCO3-)

22-26/28 mEq/L

Respiratory Acidosis

increase in PCO2 and decrease in pH

Metabolic Acidosis

relationship between pH and HCO3- is the same;


decreased

Alkalosis

pH > 7.45

Resp. Alkalosis

decreased PCO2 and increased pH (OPPOSITE)

Met. Alkalosis

increased HCO3- and increased pH (SAME)

hypovolemia

decrease volume in blood

hypervolemia

excess extracellular fluid volume

edema

expansion or accumulation of interstitial fluid volume

Anasarca

type of edema; tissue becomes hard

Hematocrit level

Male 40-54%


Female 38-47%

Normal sodium levels

135-145 mEq/L

Normal potassium levels

3.5-5.0 mEq/L

Normal Calcium levels

8.5-10.5 mg/dl

Normal Magnesium levels

1.5-2.5 mEq/L