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62 Cards in this Set

  • Front
  • Back
what is health

physical, mental and social well being
what is disease

deviation from normal body state, normally in homeostasis
what are health indicators used


-normal values within a range, vary with the tests


-technological advancements - that measure health




-what is normal levels is also affected by age, gender, genetics, environment, activity level

seven steps to health


-don't smoke


-eat vegetables fruit, high fiber low fat food, limit alcohol


-physical activity


-protect from sun


-cancer screening guidelines


-regular doctor and dentist check ups


-safety and work guidelines set up for home/wok

what is pathophysiology


functional and physical changes in body as a result of disease




deviating from homeostasis




-involves knowledge of normal anatomy and physiology


-involves knowledge of how tissues normally look like, structure


-recognizing signs and symptoms of diseases



what is disease prevention


-a focus of effective health care - preventing the problem before it arises




-maintain vaccines, screening programs, regular visits, community health programs

what factors are taken into account when taking medical history


-current and prior illnesses


allergies


hospitalizations


treatments


specific difficulties


therapy/drugs - prescription, nonprescription, herbal remedies, food supplements

it's important to keep updated on new developments and trends such as


new information discovered, knowledge


diagnostic tests


more effective drugs


new technologies


new research to prevent, control or cure disease

what is gross level assessment

looking at a person overall, and assessing their health on an overall level




organ, system level

what is microscopic level assessment


looking at tissues, cells under a microscope




looking for changes


what is a biopsy

removing small amounts of living tissue for analysis
what is an autopsy


examining the body/organs after death



what is a diagnosis

identifying the specific disease

what is the definition of causative factors

factors that lead to/caused the disease

what are predisposing factors


factors that can lead to greater risk of developing a disease




tendencies that can promote the development of disease in someone

what is pathogenesis


biological mechanisms that lead to the development of a disease




ex microbial infection, inflammation, malignancy and tissue breakdown




bacterial pathogenesis - the mechanism by which bacteria caused an infectious disease




immune system malfunction lead to cancer

what is an acute disease

disease that develops quickly/sudden onset and resolves quickly short term

what is chronic disease

develops gradual, persists long term
what is the subclinical state of a disease


illness that is present but stays below the level of clinical detection - no obvious signs or symptoms




can be identified however by pathologic changes - DNA techniques or microbial culture




ex- kidney disease, subclinical because the kidneys have great reserve, before the disease becomes worse, and symptoms/signs manifest

what is the clinical state of a disease
illness that is apparent - its signs and symptoms have manifested

what is latent state


no clinical signs or symptoms evident




ex. infectious diseases, the incubation period, before the symptoms/signs manifest




during this time can infect others

what is the incubation period


the latent state of an infectious disease




time period between being infected and when the clinical signs arise




can infect others during this time period

what is the prodromal period


early development of a disease during which one is aware of changes but signs nonspecific or absent




one is aware of changes in the body, headache, fatigue, nonspecific changes, loss of appetite, feeling of dread




but lab tests do not show anything

what are manifestations of a disease?

signs and symptoms of disease - clinical evidence




redness, swelling, fever etc.


what is a syndrome

a collection of signs and symptoms that often occur together,




often affects more than one organ

what is a sign of disease?

physical manifestations of disease that are obvious to others - rash, fever etc.

what is a symptom of disease

manifestations of a disease that are subjective to the patient - feeling nauseous, tired, pain etc.

what is a remission
manifestation of the disease subsides or becomes absent
what is a precipitating factor

conditions that trigger an ACUTE episode of a disease




an angina can be precipitated by shoveling snow on a cold day




versus a predisposing factor - factors that can lead to a disease - high cholesterol can lead to angina, make it more likely to develop angina

what is a complication

new secondary or additional problems that arise after the original disease has occurred




such as congestive heart failure after a heart attack

what is a therapy

treatment measures to promote recovery from a disease or slow progression of a disease
what is a sequlae
unwanted outcomes of a primary condition
what is convalescence

period of recover




what is prognosis

chances of the most likely outcome/recovery


probability

what is rehabilitation
part of recovery - maximizing function of diseased tissue
what is epidemiology

study of identifying causative factors of disease, tracking patterns, occurrence

what is morbidity
number of cases of a disease within a certain group

what is mortality

number of deaths as a result of a disease within a certain group
what is an epidemic

when there is a higher number of cases than expected in a certain area

what is a pandemic

when there is a higher number of cases than expected in multiple global areas
what is the occurrence of a disease
taking into account the incidence and prevalence of a disease

what is incidence

the number of new cases of a disease in a certain group in a specific time period

what is prevalence

the number of old and new cases of a disease in a specific time period in a certain group

what is a communicable disease

a disease that can be spread person to person

what is an identifiable/reportable disease

if encountered in a patient must report to the authorities

what is an autopsy/postmortem examination

after death, examining body/organs, to determine cause of death
what is atrophy


when cells shrink in size




resulting in decrease in tissue size

what is hyperplasia

when increase in number of cells




resulting in tissue size increase


what is hypertrophy


when cells increase in size




resulting in tissue size increase

what is metaplasia


mature cell type replaced by a different mature cell type




ex barretts esophagus - stratified squamous epithelium normally lines it, replaced by columnar epithelium




-is defined by metaplastic glandular changes to the distal esophagus and is linked to an increased risk of esophageal adenocarcinoma

what is dysplasia


cells varying in size and shape within a tissue, large nuclei are present and rate of mitosis is increased




can be due to irritation, cancer, infection




proliferation of cells of an abnormal type

what is anaplasia

undifferentiated cells with variable nuclear and cell structures, numerous mitotic figures



characteristic of cancer, basis of grading of a tumor

what is neoplasia


defined as new growth, neoplasms are called tu


mor




two types of tumor - benign and malignant




have unique appearance and growth pattern based on where the neoplasm arose from

what is apoptosis

programmed cell death, normal occurrence in body

what is ischemia


deficit of oxygen in cells




reduced supply of oxygenated blood to tissue or organ due to circulatory obstruction


what is hypoxia

reduced oxygen in tissue
how can tissues/cells be damaged?


-through ischemia, hypoxia


-through physical damage - excessive heat/cold, radiation


-mechanical damage - pressure, tearing


-chemicals and toxins - exogenous from the environment, endogenous from inside the body


-microorganisms - bacteria and viruses


-abnormal metabolites - genetic disorders, errors of metabolism, altered metabolism


-nutritional deficits


-imbalanced fluids, electrolytes

what is necrosis


term used when a group of cells die




how they die varies with the cause

what is liquefaction necrosis

dead cells liquefy under influence of cell enzymes




ex brain tissue dies, bacterial infections - cause a cavity or ulcer to develop

what is coagulative necrosis


when cell proteins are altered or denatured, cell retain some form




ex coagulation when eggs are cooked


MI = lack of oxygen = causes cell death

what is fat necrosis


fatty tissue broken down into fatty acids in presence of infection or certain enzymes




may increase inflammation


caseous necrosis


form of coagulation necrosis - thick yellowish cheesy substance form




TB - first stage = granuloma develops, small solid mass of macrophages and lymphocytes, covered by connective tissue, during chronic inflammation - caseous necrosis can be seen inside this mass