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38 Cards in this Set

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What is Fibrous Dysplasia?
Benign, non-neoplastic process of a single or multiple bones

Replacement of Marrow by Fibrous tissue
Monostatic Fibrous Dysplasia
-Expansile lesion = tumor is inside the bone in the Medullary Canal -> begins to grow thru the Cortex -> Bone lays down more bone to try to contain
Diagnosis?
Fibrous Dysplasia
-"Ground-glass" appearance
What is this?
Fibrous Dysplasia
-"Ground-glass" appearance
Diagnosis?
Fibrous Dysplasia
-Growth Plates light up
Diagnosis?
Fibrous Dysplasia
-background of Fibrous tissue
-Dysplastic spicules of new bone bent over like a Shepherd's Crook
What is this?
Fibrous Dysplasia
-numerous Osteoblasts lining the surface
-disorder of Osteocytes inside the bone
-there is no attempt to make Lamellar bone = Dysplastic bone
What disease?
Fibrous Dysplasia that has been treated with Bone Graft
-typically replace with Cortical bone b/c it is hard & the tumor will have a harder time chewing thru it
What is shown here?
What is McCune-Albright Syndrome?
1. Multiple sites of Fibrous Dysplasia
2. Precocious puberty
3. Cafe-au-lait spots on skin
4. Short Stature
5. occurs in very young girls
Osteoid Osteoma
Diagnosis?
What are the clinical features of Osteoid Osteoma?
1. Males; 10-20 years old
2. Bening, painful growth of the Diaphysis of a long bone, oten the tibia or femur
3. Pain is worse at night & relieved by Aspirin
Osteoid Osteoma
-central nidus of Osteoid surrounded by dense sclerotic rim of reactive cortical bone
What is this from?
Osteoid Osteoma
What is this?
Osteoid Osteoma = neoplastic proliferation of Osteoid & fibrous tissue
-Males 10-20 years old
-Pain at night that is relieved by Aspirin
What is seen here?
Osteoid Osteoma = central radiolucency surrounded by dense sclerotic rim of reactive cortical bone
What is this?
Osteoid Osteoma = central nidus of Osteoid surrounded by dense sclerotic rim of reactive cortical bone
What is this?
Osteoid Osteoma = interlacing trabeculae of woven bone surrounded by Osteoblasts
What is this?
Osteoid Osteoma = Osteoblasts are making bone matrix
-neoplastic proliferation of Osteoid & Fibrous tissue
What benign bone tumor is this?
Giant Cell Tumor
-Females 20-40
-Epiphysis of long bones
-bulky mass with pain & fractures
Diagnosis?
Giant Cell Tumor
-occurs at Epiphysis of Long bones
-"Soap bubble" appearance
Diagnosis?
Giant Cell Tumor
-often involves the Epiphysis of long bones
-locally aggressive benign tumor often around the distal femur, proximal tibial region
What is this?
Giant Cell tumor
-red-brown mass with cystic degeneration
What benign bone tumor is this?
Giant Cell tumor
-multiple Osteoclast-like Giant Cells are distributed within a background of Mononuclear Stromal cells
What benign bone tumor is this?
Locally aggressive benign bone tumor with a high rate of recurrence
Giant cell tumor = Osteoclastoma
Hereditary Multiple Osteochondromatosis
Diagnosis?
Most common benign bone tumor
Osteochrondroma (Exostosis)
Osteochondroma
What benign bone tumor?
Osteochrondroma
This is the most common benign bone tumor
Osteochrondroma
-Metaphyseal growth capped with cartilage that originates from Epiphyseal Growth Plate
What benign bone tumor is this?
Osteochondroma
-stalk of bone growth covered by cartilage cap projecting from bone
What benign bone tumor is this?
Osteochondroma
-Endochondrial ossification leads to newly synthesized bone covering medullary cavity that forms core of stalk
-Hyaline cartilage over new bone
What benign bone tumor is this?
Osteochondroma
-high magnification of the Cartilage Cap
What is seen here?
What are the clinical featurs of Osteochondroma?
1. Bone pain
2. Men < 25 years of age
3. Most common benign bone tumor
4. usually develops in Metaphysis of femur or tibia; stalk of bone growth covered by cartilage cap projecting from bone
Ollier's Multiple Enchondromatosis
Diagnosis?
Benign cartilaginous growth within the medullar cavity of bone, usually involving the hands & feet
Enchondroma
Enchondroma
Punctate calcifications...what benign bone tumor?
Enchondroma = benign cartilaginous neoplasm found in Intramedullary bone
What benign bone tumor?
Enchondroma = intramedullary cartilaginous neoplasm
What benign bone tumor?