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33 Cards in this Set
- Front
- Back
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Amantidine generic for
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Symadine
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Rimantidine generic for
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Fumadine
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Oseltamivir generic for
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Tamiflu
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Zanamivir generic for
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Relenza
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acycloguanosine generic for
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Acyclovir
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Valacyclovir generic for
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Valtrex
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Ganciclovir generic for
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Cytovene
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Cidofovi generic for
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Vistide
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Foscarnet generic for
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Foscarvir
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Ifn-alpha 2 b generic for
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(interferon)
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Ribavirin generic for
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(interferon)
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Amantidine (mechanism)
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Inhibits ion channel activity of M2 protein; revents viral uncoating and release of viral RNA into cytoplasm
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Rimantidine (mechanism)
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Inhibits ion channel activity of M2 protein; revents viral uncoating and release of viral RNA into cytoplasm
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Oseltamivir (mechanism)
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Inhibition o f neuramininidase: virons cannot be release from infected cells
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Zanamivir (mechanism)
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Inhibition o f neuramininidase: virons cannot be release from infected cells
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acycloguanosine (mechanism)
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Nucleoside analog -> competes with dGTP in viral polymerase; terminated DNA squences
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Valacyclovir (mechanism)
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Nucleoside analog -> competes with dGTP in viral polymerase; terminated DNA squences
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Ganciclovi (mechanism)r
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nucleoside analog, phosphorylated by CMV-specific physophotransferase to moonophosphate form; host cellular kinases convert monophosphate to triphosphate, triphophate competes with dGTP in viral DNA polymerase
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Cidofovir (mechanism)
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Nucleoside analod, DNA polymerase inhibitor
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Foscarnet (mechanism)
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nonnucleoside DNA polymerase inhibitor
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Ifn-alpha 2 b (mechanism)
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binds to infected cells, transcritionally activates genes which inhibit viral function
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Ribaviri (mechanism)n
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inhibits viral translation by interfering with viral RNA processing; may alo inhibit viral RNA polymerase
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Amantidine targets
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Influenza Type A
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Rimantidine targets
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Influenza Type A
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Oseltamivir targets
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Influenza Type A, Type B
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Zanamivi targetsr
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Influenza Type A, Type B
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acycloguanosine targets
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HSV
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Valacyclovir targets
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HSV
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Ganciclovi targetsr
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CMV
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Cidofovir targets
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CMV
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Foscarnet targets
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CMV
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Ifn-alpha 2 b targets
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HCV
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Ribavirin targets
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HCV
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