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5 Cards in this Set

  • Front
  • Back
Substances produced by endothelium that affects hemostasis and thrombosis
- antithrombotic factors (heparin-like substance)
- tissue plasminogen
- vasoactive factors (prostacyclin)
- platelet aggregation inhibitor
- vasodilator (endothelin)
- factors that promote thrombosis (vWF, PAI-1)
platelet receptor for collagen
glycoprotein Ia, IIa
platelet receptor for vWF
glycoprotein Ib
platelet receptor for fibrinogen
glycoprotein IIb, IIIa
how does aspirin affect platelet fnxn
 aspirin inhibits platelet function
- inhibits cyclooxygenase so thromboxane A2 is not formed
- decreases platelet aggregation