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7 Cards in this Set

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  • Back
controls on GH? TSH? Prolactin?
GH: GHRH +, somatostatin - (also insulin like growth factor I and increased glucose levels decrease it)
TSH: TRH +, somatostatin -
Prolactin: TRH +, dopamine -
GH effect?
-stimulates aa uptake and protein synthesis (growth, duh)
-anti-insulin effect
acromegalics. may see what?
DM via GH secretion (anti-insulin effect on carb metabolism)
TRH stimulation test
-see TSH def (low T4 'thyroxin')
- need to determine if hypothalmus or pituitary problem
- give TRH (the hypothalamic hormone)
Prolactin action?
- lactation
GnRH
from hypothalamus, LH and FSH from ant pituitary
- LH to Leydig cells (testosterone for spermatogenesis, etc)
- FSH to sertoli cells (MIH, Inhibin (feedback inhibs hypothalamic GnRH)
- FSH to seminiferious tubules (spermatogenesis)
Testosterone from?
MIH from?
Inhibin from? action?
testosterone: Leydig cells via LH stimualtion (from ant pit via GnRH from hypothal)

Inhibin: from sertoli cells via FSH from ant pit. neg feedback to hypothal (dec GnRH)
MIH: sertoli cells via FSH from ant pit