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44 Cards in this Set

  • Front
  • Back

types of glial tumors

diffuse astrocytoma


glioblastoma multiforme


oligodendroglioma


ependymoma

three types of CNS tumors

glial tumors


meningiomas


schwannomas

diffuse astrocytoma: age group

30s and 40s

diffuse astrocytoma: occur in what part of the brain

frontal and temporal

diffuse astrocytoma: symptoms

seizure


speech difficulty


changes in sensation, motion and vision

diffuse astrocytoma: may be...

cystic, spongy area

diffuse astrocytoma: histopathology

well differentiated neoplastic astrocytes


increased cellularity and mild nuclear atypia


low mitotic activity

diffuse astrocytoma: gliomatosis cerebri

diffuse infiltration

diffuse astrocytoma: likelihood of malignancy

high liklihood


diffuse astrocytoma, anaplastic astrocytoma, glioblastoma multiforme

diffuse astrocytoma: mean survival

6 to 8 years

glioblastoma multiforme: what is it

malignant astrocytic tumor

what is the most common brain tumor

GBM

glioblastoma multiforme: what age group gets it

older adults

glioblastoma multiforme: where is it found

temporal lobe

glioblastoma multiforme: clinical history of symptoms

is short

glioblastoma multiforme: also called

the butterfly glioma

glioblastoma multiforme: histopathology

poorly differentiated astrocytic cells


marked nuclear atypia


abudant mitosis


microvascular proliferation


necrosis


multinucleated giant cells

glioblastoma multiforme: mean survival

less than 1 year

glioblastoma multiforme: who has a better prognosis

younger patients

oligodendroglioma: what age group gets it

50s to 60s

oligodendroglioma: risk factors

radiation and viruses

oligodendroglioma: what lobe is effected

frontal

oligodendroglioma: history of symtpoms

long history

oligodendroglioma: symptoms

headache


seizures

oligodendroglioma: may be...

cystic, hemorrhagic, or have calcifications

oligodendroglioma: histopathology

increased cellularity


round homogeneous nuclei with clear cytoplasm - fried egg appearance


may have some atypia and mitosis


GFAP positivity


small vessels separate tumor into lobules chicken wire vasculature

mean survival of oligodendroglioma

4 years

meningioma: attaches to

dura

meningioma: most occur over

cerebral convexities

meningioma: ____% of spinal tumors

25

meningioma: seen in patients with

neurofibromatosis type 2

meningioma: what age group

60s and 70s

symptoms of meningioma

headache


seizure


site specific neurologic deficits

meningioma: appearance

rubbery, firm, well circumscribed

meningioma: associated with

radiaiton exposure

meningioma: histopathology

encapsulated


uniform cells with oval nuclei


whoris of cells


psammoma bodies

schwannoma: ___ of intracranial neoplasms

8%

schwannoma: ___% of spinal neoplasms

29

schwannoma: associated wtih

neurofibromatosis type 2

schwannoma: what age group

4 to 6th decade

examples of neurofibromatosis type 2

bilateral acoustic neuroma


8th cranial nerve: tinnitis, hearing difficulty, paresthesias

schwannoma: histopathology

spindle shaped neoplastic schwann cells


verocay bodies


alternating compact areas and less cellular areas

schwannoma: does it become malignant

rarely

schwannoma: tx

resection is curative