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10 Cards in this Set
- Front
- Back
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what is differentiation?
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development of specialized morphology and function in cells (away from being stem cells)
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in acquired benign changes, what is hyperplasia?
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increase in number of cells in an organ or tissue
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in acquired benign changes, what is hypertrophy?
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increase in size of cells
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in acquired benign changes, what is atrophy?
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decrease in cell size by loss of cell substance
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what may cause atrophy?
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decreased workload
loss of innervation decreased blood supply inadequate nutrition decreased endocrine stimulation aging |
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in congenital/developmental change, what is hypoplasia? agenesis?
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defective formation or incomplete development of a part
absence/failure of formation |
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in acquired premalignant change, what is metaplasia?
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abnormal transformation of an adult, fully differentiated tissue of one kind into a differentiated tissue of another kind
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how does metaplasia occur (in acquired premalignant change)?
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not the same cell
body uses metaplasia on stem cells to produce what it needs cleans away what 'died' then creates new (i.e. squamous to columnar) |
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in acquired premalignant change, what is dysplasia? other terms?
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abnormal tissue change which is less differentiated (most likely to be precancerous)
also use terms dedifferentiated or poorly differentiated |
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in acquired malignant change, what is anaplasia?
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total loss of differentiation as might occasionally be seen in malignant neoplasms
***always means cancer |
