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84 Cards in this Set

  • Front
  • Back

Lymph

Fluid similar to plasma, but does not have plasma proteins

Lymphatic vessels

Network that carries lymph from peripheral tissues to the venous system

Lymphoid tissues and lymphoid organs

Found throughout the body

4 parts of lymphatic system

1. Lymph


2. Lymphatic vessels


3. Lymphatic tissues and organs


4. Lymphocytes, phagocytes, and other immune system cells

Lymphatic and immune functions

•Drain excess interstitial fluid


•Transport dietary lipids


•Carry out immune responses


(Sewer system - cleans)

Lymphatic capillaries are for

Collection only, NOT exchange

Lymphatic flow

Blood capillaries


Interstitial space


Lymphatic capillaries


Lymphatic vessels


lymphatic ducts


Subclavian veins

Left sided

The lymphatic system s very what sided?

The lower body (lymph) all drains into the?

Thoracic duct

B cells

Plasma comes from what cells?

Lymphomas

Malignant neoplasm's involving a lymphocyte proliferation and lymph nodes

To main disorders of lymphoma

Hodgkin's lymphoma


Non-Hodgkin's lymphoma

Hodgkin's lymphoma

Initially involves a single lymph node cancer then spreads to adjacent nodes

Reed-Sternberg cells

Must be present to diagnose Hodgkin's lymphoma

Clinical presentation of Hodgkin's lymphoma

Nontender lymph nodes enlargement


Systemic symptoms


such as fever, night sweats, and unexplained weight loss

Staging classification

Stage one - single lymph node


Stage two - 2 or more lymph nodes on the same side of diaphragm


Stage three - both sides of diaphragm


Stage four - outside the lymphatic system

Treatment of Hodgkin's disease

Radiation therapy or a combination of chemotherapy and radiotherapy

Non-Hodgkin's lymphoma

Group of lymphoma


either B Cell or T lymphoma


Many different subtypes

Three types of non-Hodgkin's lymphoma

Indolent - which grow slowly


Aggressive - has rapid growth


Very aggressive - grows very rapidly

Lymphedema

Obstruction of lymphatic vessels, it is congenital

Lymphedema treatment

Diuretics, bed rest, massage of affected area, elevation of affected extremity

Elephantitis

Is a lymphedema that is due to a parasitic infection, causes significant swelling of affected extremity, treatment is to kill parasite.

Castlemans disease

Involves overgrowth of lymphoid tissue


Not cancer but similar to lymphoma

Two types of Castlemans disease

Unicentric form - affects single lymph node


Mukticentric form - affects multiple lymph nodes and tissue (Herpes, HIV patients)

Infectious mononucleosis

Epstein-Bar virus is the cause of infectious mononucleosis


(Most common in early childhood, second peak during late adolescence)

Infectious mononucleosis

Transmitted by salivary secretions


Incubation period 4-6 weeks

Infectious mononucleosis symptoms

Fatigue, malaise , fever, sore throat, lymphadenopathy.


Lymphadenopathy and pharyngitis - 1st week or two


Splenomegaly - 2nd and 3rd weeks

Mono lab findings

White blood cell count is usually elevated


liver function is abnormal

Apex

Inferior pointy part of heart

Base

Superior flat part of heart

Pericardium

Fibrous tissue, surrounds and stabilize his heart

Pericardial cavity

Is between parietal and visceral layers, contains pericardial fluid

Pericarditis

And infection of the pericardium

Epicardium

Covers the heart, outer layer

Myocardium

Middle layer, muscular wall of heart

Endocardium

Inner layer, smooth lining for heart chambers, continuous with blood vessels

The little red blood cell

Vena cava


Right atrium


tricuspid valve


right ventricle


Pulmonary valve


pulmonary trunk


pulmonary arteries -> lungs


pulmonary veins


left atrium


Mitral valve


Left ventricle


aortic valve


ascending aorta


Arch of aorta -> body

Semilunar valve's

Prevent backflow from pulmonary trunk in aorta into ventricles

Pulmonary valve

Prevents backflow into right ventricle

Aortic valve

Prevents backflow into left ventricle

Coronary artery's

Supplies blood to muscle tissue of heart


(Going out of heart)

Anastomoses

Interconnect anterior and posterior interventricular artery's

Coronary veins

Coronary sinus


greater cardiac vein


small cardiac vein


middle cardiac vein


left posterior ventricle vein


(Go into heart)

Ductus arteriosus -> Ligamentum arteriosum

Let's blood pass from pulmonary trunk to aorta (bypasses lungs)

Foramen ovale

Allows blood to pass from right atrium to the left atrium, seals off at birth forming fossa ovalis


(Hole)

Sinoatrial (SA) node

Located in right atrium, does not have a stable resting potential

Sinoatrial (SA) node

Located in right atrium, does not have a stable resting potential

Atrioventricular (AV) node

Located in the septum between atrium, both atrium contract

AV bundle (bundle of his)

Transfer signal from atrium to ventricles

Left and right bundle branches

Splits signal into L & R, extend signal down intraventricular septum him to apex

Purkinje fibers

Transfer signal from Apex to all ventricular myocardium, both ventricles contract

ECG or EKG

A recording of the electrical events in the heart obtained by electrons at specific body locations

P-wave

Atria Depolarize

QRS complex

Ventricles Depolarize

T-wave

Ventricles repolarize

P-Q interval

From start of atrial depolarization to store a ventricle depolarization (total conduction time)

Q-T interval

From ventricular depolarization to ventricular repolarization (ventricular contraction)

S-T segment

End of S to beginning of T (plateau phase)

The cardiac cycle

The period between the start of one heartbeat in the beginning of the next, include both contraction and relaxation

Atrial systole

Atrium contracts, SA node causes depolarization, P-wave, AV valve open, as a final 25 mL of 105 mL

Atrial systole

Atrium contracts, SA node causes depolarization, P-wave, AV valve open, as a final 25 mL of 105 mL

Atrial diastole

Atrium relax, atrium repolarize

Ventricular systole

Ventricles contract, QRS, AV valves shut, increased pressure SL valves (120), eject 70 mL of blood

Ventricular diastole

Atria and ventricles at rest, ventricles repolarize, pressure in ventricle drops, SL valves close, with more pressure drop AV valves open, T-wave

Mitral stenosis

Mitral valve does not open 100%, trouble filling ventricle

Mitral insufficiency

Mitral valve does not close 100%, trouble with backflow into atrium

Aortic stenosis

Are you ordered valve does not open 100%, trouble forcing blood out of left ventricle

Aortic insufficiency

Aortic valve does not close 100%, trouble with backflow into left ventricle

Cardiac output

Is the volume of blood ejected from the ventricle into the aorta every minute



Adjusted by changes in heart rate or stroke volume

Stroke volume

Volume (mL) of blood ejected per beat (about 70 mL)



Adjusted by autonomic nervous system or hormones

Heart rate

Number of beats per minute



Adjusted by changing EDV or ESV

Cardiac output equation

CO = SV x HR


70x75=5250mL = 5.25L


All blood is moved in one minute

Preload

Ventricular stretching during diastole

Contractility

Force produced during contraction, at a given preload

Afterload

Tension the ventricle produces to open the semi lunar valve and eject blood

Medulla oblongata

Controls rate in force of contraction


Located in the medulla

Sympathetic stimulation

Cardiac Excelerator nerve


Increases heart rate (tachycardia)

Parasympathetic stimulation

(CN X - vagus nerve)


Decreases heart rate (bradycardia)

Factors that increase heart rate

Thyroid hormones


epinephrine


elevated body temperature infection


exertion or exercise


smoking


stress response


pregnancy


pain

Factors that increase heart rate

Thyroid hormones


epinephrine


elevated body temperature infection


exertion or exercise


smoking


stress response


pregnancy


pain

Systolic pressure

Exerted one blood is ejected from ventricles (high)

Diastolic pressure

Sustained pressure when ventricles relax (lower)

Diagnostic test for cardiovascular function

EKG


Auscultation


echocardiography


exercise stress test


Chest x-ray films


cardiac Catheterization


angiography


Doppler studies


blood tests


arterial blood gas

General treatment for cardiac disorders

Vasodilators


Beta blockers


Calcium channel blocker's


Digoxin


Antihypertensive drugs


Adrenergic blocking drugs


Angiotensin converting enzyme


(ACE inhibitors)


Diuretics


Anticoagulants


Cholesterol lowering drugs