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113 Cards in this Set

  • Front
  • Back
s/s of a GI tract disorder (6)

-anorexia


-vomiting


-diarrhea


-constipation


-abdominal pain


-GI bleeding

occult definition

-hidden
metabolic acidosis GI cause
-diarrhea
metabolic alkalosis GI cause
-vomiting
major side effect of losing potassium

heart problems

dysphagia


definition, s/s, diagnosis, treatment

-trouble swallowing


-pain, difficulty swallowing, vomiting, weight loss, aspiration pneumonia


-barium swallow, endoscopy


-stent, mechanical dilation, drugs to increase peristalsis

mechanical obstructions


-intrinsic


-extrinsic

intrinsic


-within esophagus


ex: scleroderma, stricture

extrinsic


-outside of esophagus


ex: tumor


functional obstruction


achalasia


-involves nerve function


ex: stroke, ALS

gastrointestinal reflux disease


(GERD)


s/s, diagnosis, treatment

-heartburn, dysphagia, regurgitation, discomfort swallowing certain foods (acidic, alcohol)


-causes esophagitis and possible cancer


-barium swallow, endoscopy


-proton pump inhibitor

hiatal hernia types (2)


-sliding


-paraesophageal

hiatal hernia


definition, s/s, diagnosis, treatment

-causes gerd due to delayed stomach emptying


-gerd, dysphagia, heartburn, discomfort


-barium swallow, endoscopy


-caused by weakened diaphragmatic muscles


-careful food choices, don't eat then lie down, if severe enough may have surgery

where are hiatal hernias located?

-large intestine


-small intestine

what causes hiatal hernias?

-injury or damage weakening muscle


-old surgery site


-obstructions may be partial or complete

intussusception

-telescoping of one part of intestine into another


-causes strangulation of blood supply


-more common in infants 10-15 months

volvulus

-twisting of intestine on it mesenteric pedicle


-often includes fibrous adhesions


-causes occlusion of blood supply


-most common in middle aged/ elderly men

adhesions

-peritoneal irritation from surgery, trauma, or crohn disease


-attach to intestine, omentum, or peritoneum


-cause obstruction


-most common in small intestine

functional obstruction


-failure of motility


-drug side effect


-paralyticilius

hernia
-protrusion of intestine through weakness in abdominal muscles or inguinal rings
common hernia locations


-epigastric


-umbilical


-inguinal (most common)


-femoral


-surgery sites

pyloric obstruction


s/s

-impairs gastric emptying


-anorexia, nausea, vomiting, abdominal distention, dehydration

why does pyloric obstruction cause metabolic alkalosis?


diagnosis


treatment


-losing acid via vomit


-scope


-treatment, correct problem


ex: surgery

s/s of intestinal obstruction


-vomiting


-intermittent pain


-distention


-change in bowel sounds (high pitched)


-absence of stool

intestinal obstruction


diagnosis


treatment

-scope


-surgical

acute gastritis

-inflammation of stomach lining due to disruption of mucosal barrier


-superficial erosion


-self limiting (goes away within a few days of stimulus being removed

acute gastritis causes

-drugs or chemicals (especial NSAIDS, aspirin, alcohol)


-food contaminated with salmonella, e. coli, staph

chronic gastritis

-unrelated to acute gastritis


-thinning and degeneration with atrophy


-increases risk of gastric cancer


-more common in elderly and those with ulcers


chromic gastritis types (3)


-autoimmune


-H. Pylori


-chemical gastropathy

s/s of acute gastritis

-abdominal pain


-epigastric tenderness


-anorexia


-nausea


-vomiting


-hematemesis (bloody puke)


-melena (bloody stool)


s/s of chronic gastritis

-may be no symptoms


-sudden onset of gastric bleeding

peptic ulcer disease-


location


layers affected


most common


risk factors


-ulcers occur anywhere


-affects mucosa and submucosa


-duodenal are most common (esp. in men)


-smoking, H. Pylori, NSAIDS, aspirin, alcohol, stress

ulcers-


patho

-hyperscretion of HCL acid and pepsin


-decrease in bicarb


-penetrates mucosal barrier

gastric ulcers


-commonly in entero region


-increases risk for gastric cancer


stress ulcers




-"curling ulcer"


-caused by severe stress to body


ex: ischemia to stomach


-primary symptom is vomiting blood

s/s of ulcers

-pain beginning when stomach is empty and relived when stomach is full


-hematemesis


-melena


-periods of remission and exacerbation


(bright red bleeding, no complaints of pain)

diagnosis of ulcers


treatment


-scope


-identify H. Pylori


-antacids, ulcer coating drug- Carfate, suppress acid secretion, antihistamine, antibiotics



dumping syndrome


-rapid distention of intestine causing:


-nausea, vomiting, cramps, diarrhea, weakness, pallor, diaphoresis


-rapid transfer of fluid from vascular system to digestive system


-treatment includes limiting fluids, no fluid with meals, small meals

malabsorption syndromes (2)

-pancreatic insufficiency


-lactase insufficiency

pancreatic insufficiency


-bad nutrient absorption


-pancreatitis, pancreatic cancer


-weight loss, decreased muscle mass, fatty stool

lactase insufficiency


(lactose intolerance)

-inhibits break down of lactose
-bloating, gas, cramping, diarrhea


3 F's


-fatty, frothy, foul smelling

bile salt insufficiency involves:

-vitamin A (night blindness)


-vitamin D (bone pain)


-vitamin K (prevent bleeding)


-vitamin E (neuro deficits in kids)


(fat soluble vitamins)

bile salt insufficiency causes:


treatment:


-liver disease or obstruction of bile duct


-oral bile salts, IV replacement

ulcerative colitis


vs


crohns disease


similarities


-chronic, recurrent


-periods of remission and exacerbation


-stress increases s/s


-diarrhea big symptom


-effects men and woman equally


-weightloss

crohns disease

-affects large and small intestine


-begins in submucosa and spreads to entire wall


-turns fibrous


-inflammatory lesions are not continuous "skip lesions", cobble stone appearance


-granuloma formation


-ascending (right side)

ulcerative colitis

-ulceration of colonic mucosa layer only


-mucosa appears dark red and velvety


-narrowed lumen


-located in rectum and sigmoid colon


-diarrhea and bloody stools


- descending (left sided)


-continuous lesions

diagnosis and treatment of crohns and ulcerative colitis

-colonoscopy, barium enema


-broad spectrum antibiotics, steroids, surgery

diverticular disease


cause, diagnosis, treatment

-resembles hernia in sigmoid colon


-caused by low fiber diets


-sigmoidoscopy


-increase fiber, antibiotics, possible surgery


-may perforate bowel if left untreated

s/s of diverticular disease


-lower L abdominal cramping


-diarrhea


-constipation


-distension


-flatulence


-abscess formation


-fever


-leukocytosis

appendicitis


cause, diagnosis, treatment

-inflamed appendix


-cause is unknown


-may perforate (emergency)


-diagnosed by WBC count, CAT scan


-treatment involves surgery

s/s of appendicitis

-vague epigastric pain


-R lower quadrant pain


-rebound tenderness


-nausea and vomiting


-fever


-diarrhea


colitis


-inflamed bowel


-can be acquired through contaminated food and water

infectious colitis


cause, s/s, treatment

-C. Diff


-caused by antibiotics


-diarrhea, horrible odor, usually no systemic manifestations


-discontinue antibiotic, start fragile

irritable bowel syndrome


s/s, diagnosis, treatment

-more common in women


-constipation alternating with diarrhea, anxiety, depression, gas, bloating, nausea


-rule out all other diseases


-antispasmodic medications, add fiber to diet

liver disease



-portal hypertension causing:


1. esophageal varices (bumps lining esophagus)


2. splenomegaly (increased pressure in splenic vein)


3. jaundice


4. ascites


5. hepatic encephalopathy



ascites

- due to increased pressure in portal vein


-fluid goes into peritoneal cavity


-most common cause is cirrhosis


-weight gain


-perisentesis

hepatic encephalopathy

-caused by accumulation of ammonia


-causes brain damage

hepatitis


-A, B, C, D, and E


-differ in transmission, incubation period, and damage caused to liver (acute/ chronic)


-destroys hepatocytes during inflammation


-serologic markers used to diagnose

Hepatitis A


-fecal oral


-30 day incubation period


-acute


-get vaccine

Hepatitis B


-parental, sexual


-60-180 day incubation period


-chronic


-predisposed to liver cancer and cirrhosis

Hepatitis C

-perinatal, sexual


-35-60 day incubation period


-chronic

liver enzymes


-AST asparate aminotransferase


-ATL alanine aminotransferase


-LDH lactic dehydrogenase


-ALP alkaline phosphate


elevate with damage

phases of hepatitis


-preicteric or prodromal (flu like symptoms)


-icteric (jaundice)


-posticteric or recovery (liver enzymes become normal)

s/s of hepatitis preicteric


-flu like s/s


-malaise, fatigue


-nausea and vomiting


-anorexia


-diarrhea


-pain

s/s of hepatitis icteric


-jaundice


-pruritis


-light colored stools


-dark urine


-increased flu s/s followed by decrease

cirrhosis


-irreversible


-excessive collagen formation


-obstructs biliary and vascular channels


-forms over many years (Laennec, alcoholism)


-diagnosed off of liver enzymes


-no alcohol, treat symptoms

s/s of cirrhosis

-anorexia


-nausea


-jaundice


-ascites


-firm, large, palpable liver

cholelithiasis

-gall stones made of bile pigments and hardened cholesterol


-most common

cholecystitis


s/s


diagnosis


treatment


-stones in duct


-pain, heartburn, fat intolerance, jaundice, nausea, vomiting


-leukocytosis, elevated serum amylase 25-125


-removal of organ

pancreatitis


-acute vs chronic


-enzymes become activated while still inside pancreas


-alcohol use causes chronic

s/s of pancreatitis

-pain radiating to back


-nausea and vomiting


-jaundice


-abdominal distension


-decreased bowel sounds

diagnosis of pancreatitis


treatment

-elevated serum amylase


-elevated serum lipase 20-180


-elevated to WBC




treatment includes hospitalization

esophageal cancer


causes, diagnosis, treatment


-caused by alcohol, smoking, chronic reflux


-painless, dysphagia, pain on swallowing


-early metastasis, rapid growth


-endoscopy


-remove tumor and local lymph nodes

stomach cancer


causes, diagnosis, treatment


-salty foods, nitrates, chronic gastritis, smoking, alcohol


-anorexia, weightloss (s/s)


-early metastasis, rapid growth


-endoscopy


-chemo, radiation, surgery, nothing

colon and rectal cancer


causes, diagnosis, treatment

-high fat, low fiber diet, polyps, diverticulitis


-change in bowel habits, pain, melena, anorexia, weightloss


-screen for occult blood


-chemo, radiation, surgery, nothing

liver cancer


causes, diagnosis, treatment


-metastatic


-nausea, vomiting, anorexia, pain, fullness, ascites, jaundice


-gallbladder primary cancer is rare

pancreatic cancer


-4th leading cause of death in US


-early metastasis

hormones of anterior pituitary

-growth hormone


-prolactin


-thyrotropic hormone


-ACTH


-FSH


-LH

diabetes insipidus


vs


SIADH

-diabetes insipidus too little ADH


-usually caused by tumor or head injury


-SIADH too much ADH


-osmolality regulates amount of ADH released


s/s of diabetes insipidus


-polyuria


-nocturia


-dehydration


-hypernatremia


-low urine specific gravity


-extreme thirst

test

-water deprivation test


-keep urinating continuously

treatment

-replace ADH
s/s of SIADH


-hyponatremia


-water retention


-no edema


-neurologic impairment


-decreased urine output


-elevated urine specific gravity

treatment

-treat underlying cause


-may give diuretic

growth hormone disorders


-deficiency results in dwarfism


-excess causes giantism before puberty


-excess after puberty causes acromegaly

giantism

-too much growth hormone before puberty


-pituitary tumor


-remove tumor


-give drugs to reduce growth hormone

acromegaly


-too much growth hormone after puberty


-pituitary tumor


-remove tumor


-drugs to reduce growth hormone

thyroid disorders


-involve t4 hormone


-iodine needed for synthesis of hormones


-thyroid regulates metabolic rate


-diagnosed by blood test of t3 and t4 levels


-goiter is enlargement of thyroid gland

hyperthyroidism causes


treatment


-graves disease


-thyroid cancer


-toxic multinodular goiter


-increased levels of TSH


-remove thyroid and replacement meds


-autoimmune disorder

hyperthyroidism s/s


-sweating


-flushed, warm


-fine hair


-increased appetite


-weight loss


-nausea


-vomiting


-diarrhea


-tachycardia


-restlessness


-short attention span


-insomnia


thyrotoxic crisis


s/s


-caused by hyperthyroidism


-hyperthermia


-tachycardia


-systolic hypertension


-vomiting


-diarrhea


-agitation


-tremors


-confusion


-psychosis


-delirium


-seizures


-death



hypothyroidism


-most common


-caused by tumors and hormones


-hashimotos disease (auto immune)


-treatment includes meds


mixedema coma


-results from untreated severe hypothyroidism


-life threatening


-treatment is IV thyroid hormone replacement

s/s of hypothyroidism


-cool, dry, flaky skin


-dry, brittle hair


-poor wound healing


-fluid retention


-decreased appetite


-weight gain


-constipation


-bradycardia


-confusion


-memory loss


-depression

parathyroid function


-PTH


-regulate secretion of serum levels of calcium


-calcium levels are increased by fall in PTH


sources of calcium


-bone


-intestines


-kidneys


-phosphate excretion


-PTH excretion


-vitamin D


-strong bones, heart function, nerve transmission, blood clotting


hyperparathyroidism

-too much PTH
-primary:


PTH secreting tumor of lung


adenoma of parathyroid gland


-secondary:


chronic renal failure

hyperparathyroidism s/s

-nausea


-vomiting


-dehydration


-muscle weakness


-bone pain


-renal caliculi


-cardiac dysrhythmias


-abdominal pain


-constipation


-deposits of calcium into soft tissue


hyperparathyroidism


diagnosis and treatment


-elevated calcium levels


-diuretics, calcitonin (causes renal excretion of calcium)


hypoparathyroidism


causes

-accidental removal or injury


-possible autoimmune origin


hypoparathyroidism


s/s, diagnosis, treatment


-tetany (trousseaus sign)


-laryngospasm


-muscle spasms, nerve excitement


-hyperreflexes


-seizures


-may progress to death


-test levels


-IV calcium

diabetes mellitus

-involves alpha and beta cells


-alpha cells create glucagon


-beta cells produce insulin


-leading risk factor for CVA, MI, amputation, blindness, kidney disease, coronary artery disease, etc


-without insulin protein and fat used for energy



type 1 diabetes


-IDDM 10% of all diabetics peak at 30 or younger


-result of genetic/ environmental agents


-beta cells being destroyed


-no insulin production


-sudden onset, long preclinical period

type 2 diabetes

-NIDDM accounts for 85-90% of diabetics


-age range 40 and older


-risk factors include family history, obesity


-metabolic syndrome: raised triglycerides, raised fasting blood glucose


-insulin resistance

gestational diabetes


-glucose intolerance first detected during pregnancy


-risk factors include large baby, obesity, family history


-screening done


-increases risk of type 2 diabetes


s/s of diabetes


-polyuria


-polydipsia


-polyphasia


-weight loss


-malaise


-fatigue


-glycosuria


-dehydration


-recurrent infections


-blurred vision


-paresthesia


-genital pruritis


-increased blood glucose, increased renal blood flow, increased urine output

diabetes diagnosis


-fasting blood sugar


-glucose tolerance test


-random blood glucose


-glycosated hemoglobin (most accurate)


-fasting sugar of 100-125 is prediabetic

medical treatment for type 1 diabetes

-life long insulin replacement


-dietary management


-exercise


-SMBG

medical treatment type 2 diabetes

-oral hypoglycemic agents


-dietary management


-exercise

acute complications of diabetes


-hypoglycemia


-diabetic ketoacidosis


-hyperosmolar hyperglycemic nonketotic syndrome


-somogi effect


-dawn phenomenon


diabetic ketoacidosis


-usually occurs in type 1 due to skipping injections, being ill, poor diet, etc.


-body begins breaking down fats and proteins


-fatty acids released, ketones form, causing metabolic acidosis


-decreased fluid volume


-decreased potassium

s/s of diabetic ketoacidosis


-dry mucous membranes, weakness, malaise, rapid weak pulse, thirst, hypotension, kussmaul respirations, fruity breath, nausea, vomiting


-blood glucose over 250


-correct imbalance, insulin IV