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100 Cards in this Set

  • Front
  • Back
patho of blue sclera
defective collagen allow reflection of underlying choroidal veins
genetics achondroplasia
AD
patho of achondroplasia
mutation in FGF-R gene -> impaired prolif cartilage at growth plate
norm head/axial skeleton w/ short arms & legs; norm GH
achondroplasia
genetics osteopetrosis
AR
Sx osteopetrosis 3
patho Fx, anemia, cranial nerve compression
osteomyelitis usu spread by
hematogenous
most common pathogen of osteomyelitis
staph aureus
osteomyelitis in sickle cell pt
salmonella
TB osteomyelitis usu involve
vertebral column (Pott's dz)
punctured foot thru rubber footwear
p. aeruginosa osteomyelitis
devitalized bone
sequestra
reactive bone formation in periosteum
involucrum
draining sinus is risk factor for
SCC
osteoperosis is loss of
mineralized bone & organic bone
most common Fx of osteoperosis
vertebral column compression
most common site asceptic bone necrosis
femoral head
most common cause aseptic bone necrosis
corticosteroids
most common Fx bone in wrist
scaphoid
asceptic necrosis of ossification centers in children
osteochondrosis
asceptic necrosis of femoral head in 5 y/o boy
Legg-Calve-Perthes dz
asceptic necrosis of artiuclar epiphysis
osteochondritis dessicans
most frequent site of osteochodnritis dessicans
lat surface of medial femoral condyle
painful swelling of tibial tuberosity in boys
Osgood-Schlatter dz
Paget's dz is osteoblastic or osteoclastic
osteoclastic then osteoblastic (inc ALP)
Paget's dz is risk factor for 3
Fx, osteogenic sarcoma, high output heart failure
most common sites fibrous dysplasia 3
ribs > femur > tibia/facial bones
polyostotic bone, café au lait spots, precocious puberty
Albright's syndrome
2 CA assoc w/ fibrous dysplasia
osteogenic sarcoma,
most common benign bone tumor
osteochondroma
giant cell tumor usu inv 2
distal femur epiphysis, prox tibia
osteoma usu inv
face
enchondroma usu inv
small tubular bones of hands, feet
osteoid osteoma usu inv
prox femor
osteoblastoma inv
vertebrae
chondrosarcoma usu inv
pelvic bones, prox femur
osteogenic sarcoma usu inv
distal femur/prox tibia
ewing's sarcoma usu inv
pelvic girdle, rib
bone pain at night relieved by aspirin
osteoid osteoma
tumor lifting periosteum
Codman's triangle, osteogenic sarcoma
onionskining around bone
Ewing's sarcoma
negative birefringence means
yellow when parallel; blue when perpedicular
MSU crystals are 2
needle-shaped, neg birefringence
morning stiffness indicates
infl joint dz, osteoarthritis (inactivity)
joint crepitus indicate
osteoarthrits
common sites of osteoarthritis 4
femoral head, knee, hands, cervical/lumbar spine
ochronosis genetics
AR
ochronsis patho
def homogentisic acid
osteophytes at joint margins
osteoarthrits
pain in DIP & PIP
osteoarthrits
pain in MCP and PIP
RA
loss of priopioception & deep sensation leading to recurrent trauma
Charcot's joint
causes of Charcot's joint 3
DM, syringomyelia, tabes dorsalis
RA assoc w/ HLA
HLA-DR4
RA which type of HSR
Type 3 & 4 HSR
chronic synovitis with pannus formation
RA
joint fibrosis leading to fusion
RA
DIP flexion + PIP extension
swan-neck deformity; RA
DIP extension + PIP flexion
boutoneire deformity; RA
RA assoc lung dz 3
interstitial fibrosis, effusions, Caplan syndrome
RA assoc heme dz 3
anemia chronic dz, Felty's syndrome, AIHA
RA fx on cervical spine
subluxation of atlantoaxial joint -> compress SC, vertebral artery
RA assoc CVS dz 3
pericarditis, aortitis, vasculitis
popliteal cysts behind knee joint
RA
Ab of Sjorgren's syndrome 4
ANA, RF, Ro (SSA), La (SSB)
Sjogren's triad
RA, dry mouth, dry eyes
gout most often caused by
undersecretion uric acid -> probenecid
Dx acute gout require
joint aspiration
pseudogout inc incidence w/ 3
hemochromatosis, hemosiderosis, 1o hyperPTH
most common joint inv w/ pseudogout
knee
4 types seroneg spondyloarthropathies
AS, Reiter's, psoriasis, enteropathic
b/l sacroilitis w/ morn stiffness
anklyosing spondylitis
ankylosing spondylitis assoc w/ 2
aortitis (aortic regurg), uveitis (blurry vision)
Achilles periostis
Reiter's syndrome
sausage-shaped DIP
psoriatic arthritis
pencil-in-cup deformity
psoriatic arthritis
most common cause septic arthtritis
n. gonorrhea
erythema migrans + hemolytic anemia
Babesiosis
genetics of myotonic dystrophy
AD; CTG repeats
sustained grip w/ facial muscle weakness
myotonic dystrophy
MG initial findings 2
ptosis, diplopia improving w/ rest
shot that reverse MG Sx
tensilon
curative Tx of MG
thymectomy
hookline fingers from thickened plamar fascia
Dupuytren's contracture; fibromatosis
fibromatosis of ant abd wall
desmoid tumor
unhappy triad
damge to medial meniscus, MCL, ACL
tumor in thigh, upper limb after irradiation
fibrosarcoma
red nodule that umbilicates when squeezed
dermatofibroma
synovial sarcoma arises from
mesenchymal cells around joint, not synoviocytes
falling on outstretched hand
Colles Fx; distal radius
pain/weakness w/ active shoulder abduction
rotator cuff tear
lat epidoncylitis
tennis elbow
medial epicondylitis
golfer's elbow
pain when gripping something
tennis elbow
pain when flexing hand muscles + supinating arm
golfer's elbow
tenosynovitis of thumb
DeQuervain's tenosynovitis
bulge on dorsum of wrist when flexed
ganglion cysts
lateral curvature of spine
scoliosis
herniation of L3/L4
loss of knee jerk reflex
herniation of L5/S1
loss of ankle reflex