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10 Cards in this Set
- Front
- Back
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What is Multiple Sclerosis?
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Chronic demyelination of CNS that results in scarring
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What are the 4 different types of MS?
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Remitting-relapsing; primary progressive; secondary progressive; progressive-relapsing
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Causes of MS?
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AI - prior virus infection, genetic, environment away from equator; FHX; F>M;
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S/sx MS
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Vary due to which nerves are affected; need 2 separate episodes at different locations; vision changes; balance, memory, weakness, fatigue, spasticity, bladder dysfunction, tremor, lack of coordination or unsteady gait
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Testing MS
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hard to diagnose - MRI Demyelinating lesions in white matter; lumbar puncture Oligoclonal bands
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What is amyotrophic lateral sclerosis?
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Atrophy of upper and lower motor neurons
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Causes ALS
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idiopathic; genetic; possible excess glutamate
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S/sx ALS
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diminished muscle strength progresses to atrophy; weakness and spasms, difficulty speaking; fatigue; spastic and flaccid paralysis; respiratory infections; no intellectual or sensory impact
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What is Myasthenia Gravis
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chronic autoimmune disease; loss of acetylcholine receptors at the neuromuscular junctions
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S/Sx Myasthenia Gravis
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Muscle weakness, fatigability; eyes first; progressive muscle weakness with activity; worse with stress, heat, or physical exercise; thymus tumors
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