Patho

Front 1

Inflammatory response

Back 1

1. Blood vessels contract and dilate to move blood to site.

2. Vascular permeability increases so that...

3. White cells and plasma proteins can move through the capillary walls into the tissues to begin the task of destroying the invader in healing the injury site.

Front 2

Mast cells

Back 2

Resemble bags of granules, and are the chief activators of the inflammatory response.

Front 3

Mast cells activate the inflammatory response through what 2 functions

Back 3

Degranulation and synthesis

Front 4

Degranulation

Back 4

The process by which mast cells empty granules from their interior into the extracellular environment.

Front 5

Phase 1 of inflammation

Back 5

Acute inflammation if healing is not accomplished move to phase 2

Front 6

Phase 2 inflammation

Back 6

Chronic inflammation if healing not accomplish to move to phase 3

Front 7

Phase 3 inflammation

Back 7

Granuloma formation

Front 8

Phase 4 inflammation

Back 8

Healing (may take place after any of the first three phases)

Front 9

Histamine

Back 9

Vasoactive amine (organic compound) released during degranulation of mast cells

Front 10

Serotonin

Back 10

Released by platelets, can have effects of both vasoconstriction and vasodilation that may affect the blood flow to the affected site.

Front 11

Leukotriene

Back 11

Also known as slow reacting substances of anaphylaxis (SRS-A). They have actions similar to those of histamines, vasoconstriction vasodilation and increased permeability as well as chemotaxis

Front 12

Inflammatory response

Back 12

Complement system, coagulation system, kinin system

Front 13

Inflammation sequence

Back 13

Vascular response, increased permeability, exudation of white cells

Front 14

Monocytes

Back 14

Largest normal blood cell. During inflammation they grow several times their original size becoming macrophages.

Front 15

Neutrophils

Back 15

The first phagocytes to reach the inflamed site. They ingest bacteria dead cells and cell debris and then they die.

Front 16

Eosinophils

Back 16

Primary defense against parasites

Front 17

Hypoxia

Back 17

Due to decreased availability of oxygen.

Definition: a general oxygen deficiency or oxygen deficiency to a particular tissue or organ.

Front 18

Third-space loss

Back 18

Commonly called internal loss because fluid is lost from intravascular or intracellular spaces into interstitial space.

Front 19

Interstitial fluid

Back 19

All the fluid found outside the cell membranes, yet not within the circulatory system, making up about 25% of body water

Front 20

Obstructive shock

Back 20

Caused by obstruction the interferes with return of blood to the heart, such as pulmonary embolism, cardiac tamponade, or tension pneumothorax.