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13 Cards in this Set
- Front
- Back
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Underlying cause of CAD
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Myocardial ischemia
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Acute coronary syndromes often result from
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acute changes in chronic atherosclerotic lesions.
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Results from an imbalance of myocardial oxygen demand and myocardial blood supply
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Ischemic Heart Disease
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IHD as a result of coronary occlusion causes myocardial cells to
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-become hypoxic
-lose ability to contact after several minutes -die after 20 minutes |
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Chest pain caused by buildup of lactic acid or abnormal stretching of the ischemic muscle.
Temporary is reversible. Pallor, sweating, and dyspnea may be associated. |
Angina pectoris
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Generally predictable angina caused by luminal narrowing and hardening of the arterial walls.
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Stable angina
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Unpredictable angina that is caused by a combo of vasospasm and atherosclerotic lesions. Often occurs at rest.
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Unstable angina
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Prolonged ischemia which leads to irreversible hypoxic injury, cell death, and tissue necrosis.
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Myocardial infarction
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Begins in the subendocardial region and extends externally over a period of 3 to 6 hours.
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Necrosis
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Anaerobic metabolism kicks in to supply 65-70% of the myocardial energy requirement.
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Glycolysis
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Cardiac cells are very sensitive to low pH because acidosis may suppress impulse conduction and contractile function.
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H+ ions and lactic acid accumulation.
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Electrolyte disturbances lead to myocardial irritability.
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Loss of K+ and Ca++
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75% of MI's have this complication
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Cardiac arrhythmias
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