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30 Cards in this Set
- Front
- Back
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currant jelly stool
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intussiception probable
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krukenberg tumor
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signet ring met to the ovaries from gastric carcinoma
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NOD2 mutation
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Crohns
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large nodular, deeply infiltrative/ulcerated in the esophagus
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late adenocarcinoma
found in distal esopahgus |
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waterry diarrhea following organ transplant
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graft vs. host
t cells target GI epithlium, crypt cell necrosis w/o inflammation fluid, elyte loss, septicemia |
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rigid leather bottle lesion in stomach
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lnitis plastica advanced stomach adenocarcinoma
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staging stomach adenocarcinoma
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early has not penetrated muscularis propria
late has linitis plastica "rigid leather bottle" always advanced |
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lamina propria of stomach edematous with vascular congestion, scattered PMNS
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mild acute gastritis
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erosion and hemorrhage, lossof superficila epithlium, fibrin containing perulent exudate in lumen of stomach
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severe acute gastritis
hemorrhage with massive hemetemesis potentially fatal. |
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Nutritional deficiency from dialysis
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Vitamin C
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bowing bones, widened epiphyses, depressed sternum
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ascorbutic rickets
vitamin C deficiency |
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ulcersi n the jejunum
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thinkZollinger Ellison syndrome: gastrin producing carcinoid gastrinoma
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lesion in stomach <1cm, stained by acid digested blood. margins/base demonstrate no fibrosis, scarring or vascular thickening.
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acute ulcers. full healing may occur
Severe burns --> "curling ulcers" in somach CNS trauma--> "Cushing ulcer" esophagus, stomach & duodenum. high risk for perforations |
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Where does liver cirrhosis cause an ulcer
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duodenum
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where does uremia cause an ulcer
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stomach
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why does hypercalcemia cause ulcers?
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stimulates gastrin prodxn
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punched out stomach lesion with straight walls surrounded by scarred, thickened wall
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peptic ulcer "to be a peptic ulcer it requirres granulation tissue and necrotic debris at the base of the ulcer anything less than that is not a peptic ulcer"
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MEN1
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sydrome of tumors in multiple endocrine glands
may be underlying cause of ZE syndrome secreting gastrin |
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stomach lesion with heaped up boarders and mucin in lumen
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intestinal type adenocarcinoma (contrast to signet ring:
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stomach lesion of individual with intracytoplasmic mucin
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signet ring adenocarcinoma
signet ring cells: infiltrating individual cells which do not form glands. mucin will be in the cytoplasm. <50 yo m=f. arises de novo. decreased E cadherin. spreading means advanced, high mortality. |
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metaplastic columnar epithlium w/ mucosal glands above the GE jnx, incl intestinal goblet cells
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barret's esophagitis
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distal esophagus, flat raised initially become nodular masses, deeply infiltrative or ulcerated
mucin producing glandular tumors with intestinal type features |
adenocarcinoma
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cyst in mandible lined by squamous cells with prominent basal layer
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odontogenic keratocyst
if multiple think Gorlin's nevoid basal cell carcinoma syndrome AD: PCTH tumor suppressor KO |
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burr cells
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acanthrocytes
manifestation of abetalipoproteinemia: cannot export lipids from SI, fragile membrane |
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acanthrocytes
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burr cells
manifestation of abetalipoproteinemia: cannot export lipids from SI, fragile membrane |
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PAS positive macrophages in laminia propria of SI lysosomes filled with bacteria
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Wipple's disease
trophyerema whippelii: gram positive acetinomyete. T cell failure to recognize: do no promote macorphage destruction. multisystem complaints: backed up lymphatics: arthirtis, anemia, endocarditis, weight loss, CNS, etc. |
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severe diarrhea persistent from childhood due to autoantibodies to gut epithelium
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IPEX
Immunodysregulation Polyendocrinopathy Enteropathy foXp3 mutation |
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flaky paint
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kwashiorkor
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flag sign
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kwashiorkor
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why does H pylori cause purpura?
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anti-CagA abs cross react with platelet antigens
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